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5Y2Q

X-ray structure of acetylcholine binding protein (AChBP) complexed with a small molecule

Functional Information from GO Data
ChainGOidnamespacecontents
A0004888molecular_functiontransmembrane signaling receptor activity
A0005216molecular_functionmonoatomic ion channel activity
A0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
A0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
A0005576cellular_componentextracellular region
A0006811biological_processmonoatomic ion transport
A0007165biological_processsignal transduction
A0007268biological_processchemical synaptic transmission
A0016020cellular_componentmembrane
A0034220biological_processmonoatomic ion transmembrane transport
A0042391biological_processregulation of membrane potential
A0043005cellular_componentneuron projection
A0043083cellular_componentsynaptic cleft
A0045202cellular_componentsynapse
A0050877biological_processnervous system process
A0060078biological_processregulation of postsynaptic membrane potential
A0060079biological_processexcitatory postsynaptic potential
A0098794cellular_componentpostsynapse
A1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B0004888molecular_functiontransmembrane signaling receptor activity
B0005216molecular_functionmonoatomic ion channel activity
B0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
B0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
B0005576cellular_componentextracellular region
B0006811biological_processmonoatomic ion transport
B0007165biological_processsignal transduction
B0007268biological_processchemical synaptic transmission
B0016020cellular_componentmembrane
B0034220biological_processmonoatomic ion transmembrane transport
B0042391biological_processregulation of membrane potential
B0043005cellular_componentneuron projection
B0043083cellular_componentsynaptic cleft
B0045202cellular_componentsynapse
B0050877biological_processnervous system process
B0060078biological_processregulation of postsynaptic membrane potential
B0060079biological_processexcitatory postsynaptic potential
B0098794cellular_componentpostsynapse
B1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C0004888molecular_functiontransmembrane signaling receptor activity
C0005216molecular_functionmonoatomic ion channel activity
C0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
C0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
C0005576cellular_componentextracellular region
C0006811biological_processmonoatomic ion transport
C0007165biological_processsignal transduction
C0007268biological_processchemical synaptic transmission
C0016020cellular_componentmembrane
C0034220biological_processmonoatomic ion transmembrane transport
C0042391biological_processregulation of membrane potential
C0043005cellular_componentneuron projection
C0043083cellular_componentsynaptic cleft
C0045202cellular_componentsynapse
C0050877biological_processnervous system process
C0060078biological_processregulation of postsynaptic membrane potential
C0060079biological_processexcitatory postsynaptic potential
C0098794cellular_componentpostsynapse
C1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D0004888molecular_functiontransmembrane signaling receptor activity
D0005216molecular_functionmonoatomic ion channel activity
D0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
D0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
D0005576cellular_componentextracellular region
D0006811biological_processmonoatomic ion transport
D0007165biological_processsignal transduction
D0007268biological_processchemical synaptic transmission
D0016020cellular_componentmembrane
D0034220biological_processmonoatomic ion transmembrane transport
D0042391biological_processregulation of membrane potential
D0043005cellular_componentneuron projection
D0043083cellular_componentsynaptic cleft
D0045202cellular_componentsynapse
D0050877biological_processnervous system process
D0060078biological_processregulation of postsynaptic membrane potential
D0060079biological_processexcitatory postsynaptic potential
D0098794cellular_componentpostsynapse
D1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
E0004888molecular_functiontransmembrane signaling receptor activity
E0005216molecular_functionmonoatomic ion channel activity
E0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
E0005231molecular_functionexcitatory extracellular ligand-gated monoatomic ion channel activity
E0005576cellular_componentextracellular region
E0006811biological_processmonoatomic ion transport
E0007165biological_processsignal transduction
E0007268biological_processchemical synaptic transmission
E0016020cellular_componentmembrane
E0034220biological_processmonoatomic ion transmembrane transport
E0042391biological_processregulation of membrane potential
E0043005cellular_componentneuron projection
E0043083cellular_componentsynaptic cleft
E0045202cellular_componentsynapse
E0050877biological_processnervous system process
E0060078biological_processregulation of postsynaptic membrane potential
E0060079biological_processexcitatory postsynaptic potential
E0098794cellular_componentpostsynapse
E1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue 8L3 D 301
ChainResidue
AGLN55
DHOH411
AARG104
ALEU112
AMET114
DTRP143
DTHR144
DTYR185
DCYS187
DTYR192

site_idAC2
Number of Residues13
Detailsbinding site for residue 8L3 D 302
ChainResidue
DTRP53
DGLN55
DARG104
DLEU112
DMET114
DTYR164
DHOH420
ETYR89
ETRP143
ETHR144
ETYR185
ECYS187
ETYR192

site_idAC3
Number of Residues9
Detailsbinding site for residue 8L3 A 301
ChainResidue
ATYR89
ASER142
ATRP143
ATYR185
ACYS187
ATYR192
AHOH422
BLEU112
BMET114

site_idAC4
Number of Residues13
Detailsbinding site for residue 8L3 B 301
ChainResidue
BTYR89
BSER142
BTRP143
BTYR185
BCYS187
BCYS188
BTYR192
CGLN55
CARG104
CLEU112
CMET114
CTYR164
CHOH414

site_idAC5
Number of Residues12
Detailsbinding site for residue 8L3 C 301
ChainResidue
CTYR89
CSER142
CTRP143
CTYR185
CCYS187
CCYS188
CTYR192
ETRP53
EGLN55
ELEU112
EMET114
EHOH312

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305
ChainResidueDetails
DASN66
AASN66
BASN66
CASN66
EASN66

222624

PDB entries from 2024-07-17

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