5XXX
GMPCPP-microtubule complexed with nucleotide-free KIF5C
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000226 | biological_process | microtubule cytoskeleton organization |
A | 0000278 | biological_process | mitotic cell cycle |
A | 0005200 | molecular_function | structural constituent of cytoskeleton |
A | 0005525 | molecular_function | GTP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005856 | cellular_component | cytoskeleton |
A | 0005874 | cellular_component | microtubule |
A | 0007017 | biological_process | microtubule-based process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0031514 | cellular_component | motile cilium |
A | 0046872 | molecular_function | metal ion binding |
B | 0000226 | biological_process | microtubule cytoskeleton organization |
B | 0000278 | biological_process | mitotic cell cycle |
B | 0003924 | molecular_function | GTPase activity |
B | 0005200 | molecular_function | structural constituent of cytoskeleton |
B | 0005515 | molecular_function | protein binding |
B | 0005525 | molecular_function | GTP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005856 | cellular_component | cytoskeleton |
B | 0005874 | cellular_component | microtubule |
B | 0007017 | biological_process | microtubule-based process |
B | 0046872 | molecular_function | metal ion binding |
C | 0000226 | biological_process | microtubule cytoskeleton organization |
C | 0000278 | biological_process | mitotic cell cycle |
C | 0005200 | molecular_function | structural constituent of cytoskeleton |
C | 0005525 | molecular_function | GTP binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0005856 | cellular_component | cytoskeleton |
C | 0005874 | cellular_component | microtubule |
C | 0007017 | biological_process | microtubule-based process |
C | 0016787 | molecular_function | hydrolase activity |
C | 0031514 | cellular_component | motile cilium |
C | 0046872 | molecular_function | metal ion binding |
D | 0000226 | biological_process | microtubule cytoskeleton organization |
D | 0000278 | biological_process | mitotic cell cycle |
D | 0003924 | molecular_function | GTPase activity |
D | 0005200 | molecular_function | structural constituent of cytoskeleton |
D | 0005515 | molecular_function | protein binding |
D | 0005525 | molecular_function | GTP binding |
D | 0005737 | cellular_component | cytoplasm |
D | 0005856 | cellular_component | cytoskeleton |
D | 0005874 | cellular_component | microtubule |
D | 0007017 | biological_process | microtubule-based process |
D | 0046872 | molecular_function | metal ion binding |
E | 0000226 | biological_process | microtubule cytoskeleton organization |
E | 0000278 | biological_process | mitotic cell cycle |
E | 0005200 | molecular_function | structural constituent of cytoskeleton |
E | 0005525 | molecular_function | GTP binding |
E | 0005737 | cellular_component | cytoplasm |
E | 0005856 | cellular_component | cytoskeleton |
E | 0005874 | cellular_component | microtubule |
E | 0007017 | biological_process | microtubule-based process |
E | 0016787 | molecular_function | hydrolase activity |
E | 0031514 | cellular_component | motile cilium |
E | 0046872 | molecular_function | metal ion binding |
F | 0000226 | biological_process | microtubule cytoskeleton organization |
F | 0000278 | biological_process | mitotic cell cycle |
F | 0003924 | molecular_function | GTPase activity |
F | 0005200 | molecular_function | structural constituent of cytoskeleton |
F | 0005515 | molecular_function | protein binding |
F | 0005525 | molecular_function | GTP binding |
F | 0005737 | cellular_component | cytoplasm |
F | 0005856 | cellular_component | cytoskeleton |
F | 0005874 | cellular_component | microtubule |
F | 0007017 | biological_process | microtubule-based process |
F | 0046872 | molecular_function | metal ion binding |
G | 0000226 | biological_process | microtubule cytoskeleton organization |
G | 0000278 | biological_process | mitotic cell cycle |
G | 0005200 | molecular_function | structural constituent of cytoskeleton |
G | 0005525 | molecular_function | GTP binding |
G | 0005737 | cellular_component | cytoplasm |
G | 0005856 | cellular_component | cytoskeleton |
G | 0005874 | cellular_component | microtubule |
G | 0007017 | biological_process | microtubule-based process |
G | 0016787 | molecular_function | hydrolase activity |
G | 0031514 | cellular_component | motile cilium |
G | 0046872 | molecular_function | metal ion binding |
H | 0000226 | biological_process | microtubule cytoskeleton organization |
H | 0000278 | biological_process | mitotic cell cycle |
H | 0003924 | molecular_function | GTPase activity |
H | 0005200 | molecular_function | structural constituent of cytoskeleton |
H | 0005515 | molecular_function | protein binding |
H | 0005525 | molecular_function | GTP binding |
H | 0005737 | cellular_component | cytoplasm |
H | 0005856 | cellular_component | cytoskeleton |
H | 0005874 | cellular_component | microtubule |
H | 0007017 | biological_process | microtubule-based process |
H | 0046872 | molecular_function | metal ion binding |
I | 0000226 | biological_process | microtubule cytoskeleton organization |
I | 0000278 | biological_process | mitotic cell cycle |
I | 0005200 | molecular_function | structural constituent of cytoskeleton |
I | 0005525 | molecular_function | GTP binding |
I | 0005737 | cellular_component | cytoplasm |
I | 0005856 | cellular_component | cytoskeleton |
I | 0005874 | cellular_component | microtubule |
I | 0007017 | biological_process | microtubule-based process |
I | 0016787 | molecular_function | hydrolase activity |
I | 0031514 | cellular_component | motile cilium |
I | 0046872 | molecular_function | metal ion binding |
J | 0000226 | biological_process | microtubule cytoskeleton organization |
J | 0000278 | biological_process | mitotic cell cycle |
J | 0003924 | molecular_function | GTPase activity |
J | 0005200 | molecular_function | structural constituent of cytoskeleton |
J | 0005515 | molecular_function | protein binding |
J | 0005525 | molecular_function | GTP binding |
J | 0005737 | cellular_component | cytoplasm |
J | 0005856 | cellular_component | cytoskeleton |
J | 0005874 | cellular_component | microtubule |
J | 0007017 | biological_process | microtubule-based process |
J | 0046872 | molecular_function | metal ion binding |
K | 0000226 | biological_process | microtubule cytoskeleton organization |
K | 0000278 | biological_process | mitotic cell cycle |
K | 0005200 | molecular_function | structural constituent of cytoskeleton |
K | 0005525 | molecular_function | GTP binding |
K | 0005737 | cellular_component | cytoplasm |
K | 0005856 | cellular_component | cytoskeleton |
K | 0005874 | cellular_component | microtubule |
K | 0007017 | biological_process | microtubule-based process |
K | 0016787 | molecular_function | hydrolase activity |
K | 0031514 | cellular_component | motile cilium |
K | 0046872 | molecular_function | metal ion binding |
L | 0000226 | biological_process | microtubule cytoskeleton organization |
L | 0000278 | biological_process | mitotic cell cycle |
L | 0003924 | molecular_function | GTPase activity |
L | 0005200 | molecular_function | structural constituent of cytoskeleton |
L | 0005515 | molecular_function | protein binding |
L | 0005525 | molecular_function | GTP binding |
L | 0005737 | cellular_component | cytoplasm |
L | 0005856 | cellular_component | cytoskeleton |
L | 0005874 | cellular_component | microtubule |
L | 0007017 | biological_process | microtubule-based process |
L | 0046872 | molecular_function | metal ion binding |
M | 0000226 | biological_process | microtubule cytoskeleton organization |
M | 0000278 | biological_process | mitotic cell cycle |
M | 0005200 | molecular_function | structural constituent of cytoskeleton |
M | 0005525 | molecular_function | GTP binding |
M | 0005737 | cellular_component | cytoplasm |
M | 0005856 | cellular_component | cytoskeleton |
M | 0005874 | cellular_component | microtubule |
M | 0007017 | biological_process | microtubule-based process |
M | 0016787 | molecular_function | hydrolase activity |
M | 0031514 | cellular_component | motile cilium |
M | 0046872 | molecular_function | metal ion binding |
N | 0000226 | biological_process | microtubule cytoskeleton organization |
N | 0000278 | biological_process | mitotic cell cycle |
N | 0003924 | molecular_function | GTPase activity |
N | 0005200 | molecular_function | structural constituent of cytoskeleton |
N | 0005515 | molecular_function | protein binding |
N | 0005525 | molecular_function | GTP binding |
N | 0005737 | cellular_component | cytoplasm |
N | 0005856 | cellular_component | cytoskeleton |
N | 0005874 | cellular_component | microtubule |
N | 0007017 | biological_process | microtubule-based process |
N | 0046872 | molecular_function | metal ion binding |
O | 0000226 | biological_process | microtubule cytoskeleton organization |
O | 0000278 | biological_process | mitotic cell cycle |
O | 0005200 | molecular_function | structural constituent of cytoskeleton |
O | 0005525 | molecular_function | GTP binding |
O | 0005737 | cellular_component | cytoplasm |
O | 0005856 | cellular_component | cytoskeleton |
O | 0005874 | cellular_component | microtubule |
O | 0007017 | biological_process | microtubule-based process |
O | 0016787 | molecular_function | hydrolase activity |
O | 0031514 | cellular_component | motile cilium |
O | 0046872 | molecular_function | metal ion binding |
P | 0000226 | biological_process | microtubule cytoskeleton organization |
P | 0000278 | biological_process | mitotic cell cycle |
P | 0003924 | molecular_function | GTPase activity |
P | 0005200 | molecular_function | structural constituent of cytoskeleton |
P | 0005515 | molecular_function | protein binding |
P | 0005525 | molecular_function | GTP binding |
P | 0005737 | cellular_component | cytoplasm |
P | 0005856 | cellular_component | cytoskeleton |
P | 0005874 | cellular_component | microtubule |
P | 0007017 | biological_process | microtubule-based process |
P | 0046872 | molecular_function | metal ion binding |
Q | 0000226 | biological_process | microtubule cytoskeleton organization |
Q | 0000278 | biological_process | mitotic cell cycle |
Q | 0005200 | molecular_function | structural constituent of cytoskeleton |
Q | 0005525 | molecular_function | GTP binding |
Q | 0005737 | cellular_component | cytoplasm |
Q | 0005856 | cellular_component | cytoskeleton |
Q | 0005874 | cellular_component | microtubule |
Q | 0007017 | biological_process | microtubule-based process |
Q | 0016787 | molecular_function | hydrolase activity |
Q | 0031514 | cellular_component | motile cilium |
Q | 0046872 | molecular_function | metal ion binding |
R | 0000226 | biological_process | microtubule cytoskeleton organization |
R | 0000278 | biological_process | mitotic cell cycle |
R | 0003924 | molecular_function | GTPase activity |
R | 0005200 | molecular_function | structural constituent of cytoskeleton |
R | 0005515 | molecular_function | protein binding |
R | 0005525 | molecular_function | GTP binding |
R | 0005737 | cellular_component | cytoplasm |
R | 0005856 | cellular_component | cytoskeleton |
R | 0005874 | cellular_component | microtubule |
R | 0007017 | biological_process | microtubule-based process |
R | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue GTP A 501 |
Chain | Residue |
A | GLN11 |
A | TYR224 |
A | ASN228 |
A | MG502 |
A | HOH601 |
B | ASN249 |
B | LYS254 |
A | ALA99 |
A | ASN101 |
A | SER140 |
A | GLY143 |
A | GLY144 |
A | THR145 |
A | GLY146 |
A | ASN206 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue MG A 502 |
Chain | Residue |
A | GTP501 |
A | HOH601 |
A | HOH602 |
A | HOH603 |
A | HOH604 |
site_id | AC3 |
Number of Residues | 17 |
Details | binding site for residue G2P B 501 |
Chain | Residue |
B | GLY10 |
B | GLN11 |
B | CYS12 |
B | GLN15 |
B | ALA99 |
B | GLY100 |
B | ASN101 |
B | SER140 |
B | GLY144 |
B | THR145 |
B | GLY146 |
B | ASP179 |
B | GLU183 |
B | ASN206 |
B | TYR224 |
B | ASN228 |
B | MG502 |
site_id | AC4 |
Number of Residues | 1 |
Details | binding site for residue MG B 502 |
Chain | Residue |
B | G2P501 |
site_id | AC5 |
Number of Residues | 15 |
Details | binding site for residue GTP C 501 |
Chain | Residue |
C | GLN11 |
C | ALA99 |
C | ASN101 |
C | SER140 |
C | GLY143 |
C | GLY144 |
C | THR145 |
C | GLY146 |
C | ASN206 |
C | TYR224 |
C | ASN228 |
C | MG502 |
C | HOH601 |
D | ASN249 |
D | LYS254 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue MG C 502 |
Chain | Residue |
C | GTP501 |
C | HOH601 |
C | HOH602 |
C | HOH603 |
C | HOH604 |
site_id | AC7 |
Number of Residues | 17 |
Details | binding site for residue G2P D 501 |
Chain | Residue |
D | GLY10 |
D | GLN11 |
D | CYS12 |
D | GLN15 |
D | ALA99 |
D | GLY100 |
D | ASN101 |
D | SER140 |
D | GLY144 |
D | THR145 |
D | GLY146 |
D | ASP179 |
D | GLU183 |
D | ASN206 |
D | TYR224 |
D | ASN228 |
D | MG502 |
site_id | AC8 |
Number of Residues | 1 |
Details | binding site for residue MG D 502 |
Chain | Residue |
D | G2P501 |
site_id | AC9 |
Number of Residues | 15 |
Details | binding site for residue GTP E 501 |
Chain | Residue |
E | GLN11 |
E | ALA99 |
E | ASN101 |
E | SER140 |
E | GLY143 |
E | GLY144 |
E | THR145 |
E | GLY146 |
E | ASN206 |
E | TYR224 |
E | ASN228 |
E | MG502 |
E | HOH601 |
F | ASN249 |
F | LYS254 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue MG E 502 |
Chain | Residue |
E | GTP501 |
E | HOH601 |
E | HOH602 |
E | HOH603 |
E | HOH604 |
site_id | AD2 |
Number of Residues | 17 |
Details | binding site for residue G2P F 501 |
Chain | Residue |
F | GLN15 |
F | ALA99 |
F | GLY100 |
F | ASN101 |
F | SER140 |
F | GLY144 |
F | THR145 |
F | GLY146 |
F | ASP179 |
F | GLU183 |
F | ASN206 |
F | TYR224 |
F | ASN228 |
F | MG502 |
F | GLY10 |
F | GLN11 |
F | CYS12 |
site_id | AD3 |
Number of Residues | 1 |
Details | binding site for residue MG F 502 |
Chain | Residue |
F | G2P501 |
site_id | AD4 |
Number of Residues | 16 |
Details | binding site for residue GTP G 501 |
Chain | Residue |
G | GLN11 |
G | ALA99 |
G | ASN101 |
G | SER140 |
G | GLY143 |
G | GLY144 |
G | THR145 |
G | GLY146 |
G | ASN206 |
G | TYR224 |
G | ASN228 |
G | MG502 |
G | HOH601 |
H | LEU248 |
H | ASN249 |
H | LYS254 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for residue MG G 502 |
Chain | Residue |
G | GTP501 |
G | HOH601 |
G | HOH602 |
G | HOH603 |
G | HOH604 |
site_id | AD6 |
Number of Residues | 17 |
Details | binding site for residue G2P H 501 |
Chain | Residue |
H | GLY10 |
H | GLN11 |
H | CYS12 |
H | GLN15 |
H | ALA99 |
H | GLY100 |
H | ASN101 |
H | SER140 |
H | GLY144 |
H | THR145 |
H | GLY146 |
H | ASP179 |
H | GLU183 |
H | ASN206 |
H | TYR224 |
H | ASN228 |
H | MG502 |
site_id | AD7 |
Number of Residues | 1 |
Details | binding site for residue MG H 502 |
Chain | Residue |
H | G2P501 |
site_id | AD8 |
Number of Residues | 17 |
Details | binding site for residue GTP I 501 |
Chain | Residue |
I | GLN11 |
I | ALA99 |
I | ASN101 |
I | SER140 |
I | GLY143 |
I | GLY144 |
I | THR145 |
I | GLY146 |
I | ASN206 |
I | TYR224 |
I | ASN228 |
I | MG502 |
I | HOH601 |
J | GLN247 |
J | LEU248 |
J | ASN249 |
J | LYS254 |
site_id | AD9 |
Number of Residues | 5 |
Details | binding site for residue MG I 502 |
Chain | Residue |
I | GTP501 |
I | HOH601 |
I | HOH602 |
I | HOH603 |
I | HOH604 |
site_id | AE1 |
Number of Residues | 17 |
Details | binding site for residue G2P J 501 |
Chain | Residue |
J | GLY10 |
J | GLN11 |
J | CYS12 |
J | GLN15 |
J | ALA99 |
J | GLY100 |
J | ASN101 |
J | SER140 |
J | GLY144 |
J | THR145 |
J | GLY146 |
J | ASP179 |
J | GLU183 |
J | ASN206 |
J | TYR224 |
J | ASN228 |
J | MG502 |
site_id | AE2 |
Number of Residues | 1 |
Details | binding site for residue MG J 502 |
Chain | Residue |
J | G2P501 |
site_id | AE3 |
Number of Residues | 16 |
Details | binding site for residue GTP K 501 |
Chain | Residue |
K | GLN11 |
K | ALA99 |
K | ASN101 |
K | SER140 |
K | GLY143 |
K | GLY144 |
K | THR145 |
K | GLY146 |
K | ASN206 |
K | TYR224 |
K | ASN228 |
K | MG502 |
K | HOH601 |
L | LEU248 |
L | ASN249 |
L | LYS254 |
site_id | AE4 |
Number of Residues | 5 |
Details | binding site for residue MG K 502 |
Chain | Residue |
K | GTP501 |
K | HOH601 |
K | HOH602 |
K | HOH603 |
K | HOH604 |
site_id | AE5 |
Number of Residues | 17 |
Details | binding site for residue G2P L 501 |
Chain | Residue |
L | GLY10 |
L | GLN11 |
L | CYS12 |
L | GLN15 |
L | ALA99 |
L | GLY100 |
L | ASN101 |
L | SER140 |
L | GLY144 |
L | THR145 |
L | GLY146 |
L | ASP179 |
L | GLU183 |
L | ASN206 |
L | TYR224 |
L | ASN228 |
L | MG502 |
site_id | AE6 |
Number of Residues | 1 |
Details | binding site for residue MG L 502 |
Chain | Residue |
L | G2P501 |
site_id | AE7 |
Number of Residues | 15 |
Details | binding site for residue GTP M 501 |
Chain | Residue |
M | GLN11 |
M | ALA99 |
M | ASN101 |
M | SER140 |
M | GLY143 |
M | GLY144 |
M | THR145 |
M | GLY146 |
M | ASN206 |
M | TYR224 |
M | ASN228 |
M | MG502 |
M | HOH601 |
N | ASN249 |
N | LYS254 |
site_id | AE8 |
Number of Residues | 5 |
Details | binding site for residue MG M 502 |
Chain | Residue |
M | GTP501 |
M | HOH601 |
M | HOH602 |
M | HOH603 |
M | HOH604 |
site_id | AE9 |
Number of Residues | 17 |
Details | binding site for residue G2P N 501 |
Chain | Residue |
N | GLY10 |
N | GLN11 |
N | CYS12 |
N | GLN15 |
N | ALA99 |
N | GLY100 |
N | ASN101 |
N | SER140 |
N | GLY144 |
N | THR145 |
N | GLY146 |
N | ASP179 |
N | GLU183 |
N | ASN206 |
N | TYR224 |
N | ASN228 |
N | MG502 |
site_id | AF1 |
Number of Residues | 1 |
Details | binding site for residue MG N 502 |
Chain | Residue |
N | G2P501 |
site_id | AF2 |
Number of Residues | 15 |
Details | binding site for residue GTP O 501 |
Chain | Residue |
O | GLN11 |
O | ALA99 |
O | ASN101 |
O | SER140 |
O | GLY143 |
O | GLY144 |
O | THR145 |
O | GLY146 |
O | ASN206 |
O | TYR224 |
O | ASN228 |
O | MG502 |
O | HOH601 |
P | ASN249 |
P | LYS254 |
site_id | AF3 |
Number of Residues | 5 |
Details | binding site for residue MG O 502 |
Chain | Residue |
O | GTP501 |
O | HOH601 |
O | HOH602 |
O | HOH603 |
O | HOH604 |
site_id | AF4 |
Number of Residues | 17 |
Details | binding site for residue G2P P 501 |
Chain | Residue |
P | GLY10 |
P | GLN11 |
P | CYS12 |
P | GLN15 |
P | ALA99 |
P | GLY100 |
P | ASN101 |
P | SER140 |
P | GLY144 |
P | THR145 |
P | GLY146 |
P | ASP179 |
P | GLU183 |
P | ASN206 |
P | TYR224 |
P | ASN228 |
P | MG502 |
site_id | AF5 |
Number of Residues | 1 |
Details | binding site for residue MG P 502 |
Chain | Residue |
P | G2P501 |
site_id | AF6 |
Number of Residues | 15 |
Details | binding site for residue GTP Q 501 |
Chain | Residue |
Q | GLN11 |
Q | ALA99 |
Q | ASN101 |
Q | SER140 |
Q | GLY143 |
Q | GLY144 |
Q | THR145 |
Q | GLY146 |
Q | ASN206 |
Q | TYR224 |
Q | ASN228 |
Q | MG502 |
Q | HOH601 |
R | ASN249 |
R | LYS254 |
site_id | AF7 |
Number of Residues | 5 |
Details | binding site for residue MG Q 502 |
Chain | Residue |
Q | GTP501 |
Q | HOH601 |
Q | HOH602 |
Q | HOH603 |
Q | HOH604 |
site_id | AF8 |
Number of Residues | 17 |
Details | binding site for residue G2P R 501 |
Chain | Residue |
R | GLY10 |
R | GLN11 |
R | CYS12 |
R | GLN15 |
R | ALA99 |
R | GLY100 |
R | ASN101 |
R | SER140 |
R | GLY144 |
R | THR145 |
R | GLY146 |
R | ASP179 |
R | GLU183 |
R | ASN206 |
R | TYR224 |
R | ASN228 |
R | MG502 |
site_id | AF9 |
Number of Residues | 1 |
Details | binding site for residue MG R 502 |
Chain | Residue |
R | G2P501 |
site_id | AG1 |
Number of Residues | 28 |
Details | binding site for Di-peptide VAL D 177 and ASN G 329 |
Chain | Residue |
C | VAL177 |
C | TYR210 |
D | SER174 |
D | PRO175 |
D | LYS176 |
D | SER178 |
D | MET325 |
D | LYS326 |
D | GLU327 |
D | VAL328 |
D | GLU330 |
D | GLN331 |
D | MET332 |
D | LEU333 |
G | ALA174 |
G | GLN176 |
G | SER178 |
G | GLU207 |
G | PRO325 |
G | LYS326 |
G | ASP327 |
G | VAL328 |
G | ALA330 |
G | ALA331 |
G | ILE332 |
G | ALA333 |
H | ASP329 |
H | GLU330 |
site_id | AG2 |
Number of Residues | 28 |
Details | binding site for Di-peptide VAL F 177 and ASN K 329 |
Chain | Residue |
E | VAL177 |
E | TYR210 |
F | SER174 |
F | PRO175 |
F | LYS176 |
F | SER178 |
F | MET325 |
F | LYS326 |
F | GLU327 |
F | VAL328 |
F | GLU330 |
F | GLN331 |
F | MET332 |
F | LEU333 |
K | ALA174 |
K | GLN176 |
K | SER178 |
K | GLU207 |
K | PRO325 |
K | LYS326 |
K | ASP327 |
K | VAL328 |
K | ALA330 |
K | ALA331 |
K | ILE332 |
K | ALA333 |
L | ASP329 |
L | GLU330 |
site_id | AG3 |
Number of Residues | 21 |
Details | binding site for Di-peptide ARG J 2 and GLU I 97 |
Chain | Residue |
B | GLN96 |
I | GLU3 |
I | THR51 |
I | LEU70 |
I | GLU71 |
I | LYS96 |
I | ASP98 |
I | ILE110 |
I | GLY131 |
I | GLN133 |
J | GLU3 |
J | VAL51 |
J | LEU70 |
J | GLN96 |
J | GLY98 |
J | LYS105 |
J | GLU110 |
J | CYS131 |
J | GLN133 |
J | ASP251 |
J | ARG253 |
site_id | AG4 |
Number of Residues | 28 |
Details | binding site for Di-peptide VAL N 177 and ASN C 329 |
Chain | Residue |
C | ALA174 |
C | GLN176 |
C | SER178 |
C | GLU207 |
C | PRO325 |
C | LYS326 |
C | ASP327 |
C | VAL328 |
C | ALA330 |
C | ALA331 |
C | ILE332 |
C | ALA333 |
D | ASP329 |
D | GLU330 |
M | VAL177 |
M | TYR210 |
N | SER174 |
N | PRO175 |
N | LYS176 |
N | SER178 |
N | MET325 |
N | LYS326 |
N | GLU327 |
N | VAL328 |
N | GLU330 |
N | GLN331 |
N | MET332 |
N | LEU333 |
site_id | AG5 |
Number of Residues | 24 |
Details | binding site for Di-peptide VAL N 181 and GLY C 350 |
Chain | Residue |
C | ALA180 |
C | VAL182 |
C | GLU183 |
C | PRO348 |
C | THR349 |
C | PHE351 |
C | LYS352 |
C | MET398 |
C | PHE404 |
D | ASN258 |
D | ILE347 |
D | LYS352 |
N | THR180 |
N | VAL182 |
N | GLU183 |
N | VAL315 |
N | PHE343 |
N | VAL344 |
N | ILE347 |
N | PRO348 |
N | ASN349 |
N | VAL351 |
N | MET398 |
N | PHE404 |
site_id | AG6 |
Number of Residues | 28 |
Details | binding site for Di-peptide VAL R 177 and ASN E 329 |
Chain | Residue |
E | ALA174 |
E | GLN176 |
E | SER178 |
E | GLU207 |
E | PRO325 |
E | LYS326 |
E | ASP327 |
E | VAL328 |
E | ALA330 |
E | ALA331 |
E | ILE332 |
E | ALA333 |
F | ASP329 |
F | GLU330 |
Q | VAL177 |
Q | TYR210 |
R | SER174 |
R | PRO175 |
R | LYS176 |
R | SER178 |
R | MET325 |
R | LYS326 |
R | GLU327 |
R | VAL328 |
R | GLU330 |
R | GLN331 |
R | MET332 |
R | LEU333 |
site_id | AG7 |
Number of Residues | 24 |
Details | binding site for Di-peptide VAL R 181 and GLY E 350 |
Chain | Residue |
E | ALA180 |
E | VAL182 |
E | GLU183 |
E | PRO348 |
E | THR349 |
E | PHE351 |
E | LYS352 |
E | MET398 |
E | PHE404 |
F | ASN258 |
F | ILE347 |
F | LYS352 |
R | THR180 |
R | VAL182 |
R | GLU183 |
R | VAL315 |
R | PHE343 |
R | VAL344 |
R | ILE347 |
R | PRO348 |
R | ASN349 |
R | VAL351 |
R | MET398 |
R | PHE404 |
Functional Information from PROSITE/UniProt
site_id | PS00227 |
Number of Residues | 7 |
Details | TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG |
Chain | Residue | Details |
A | GLY142-GLY148 | |
B | GLY142-GLY148 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 63 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q13509 |
Chain | Residue | Details |
B | GLN11 | |
D | GLY144 | |
D | THR145 | |
D | GLY146 | |
D | ASN206 | |
D | ASN228 | |
F | GLN11 | |
F | SER140 | |
F | GLY144 | |
F | THR145 | |
F | GLY146 | |
B | SER140 | |
F | ASN206 | |
F | ASN228 | |
H | GLN11 | |
H | SER140 | |
H | GLY144 | |
H | THR145 | |
H | GLY146 | |
H | ASN206 | |
H | ASN228 | |
J | GLN11 | |
B | GLY144 | |
J | SER140 | |
J | GLY144 | |
J | THR145 | |
J | GLY146 | |
J | ASN206 | |
J | ASN228 | |
L | GLN11 | |
L | SER140 | |
L | GLY144 | |
L | THR145 | |
B | THR145 | |
L | GLY146 | |
L | ASN206 | |
L | ASN228 | |
N | GLN11 | |
N | SER140 | |
N | GLY144 | |
N | THR145 | |
N | GLY146 | |
N | ASN206 | |
N | ASN228 | |
B | GLY146 | |
P | GLN11 | |
P | SER140 | |
P | GLY144 | |
P | THR145 | |
P | GLY146 | |
P | ASN206 | |
P | ASN228 | |
R | GLN11 | |
R | SER140 | |
R | GLY144 | |
B | ASN206 | |
R | THR145 | |
R | GLY146 | |
R | ASN206 | |
R | ASN228 | |
B | ASN228 | |
D | GLN11 | |
D | SER140 |
site_id | SWS_FT_FI2 |
Number of Residues | 9 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:P68363 |
Chain | Residue | Details |
B | GLU71 | |
C | GLU71 | |
C | SER140 | |
C | GLY144 | |
C | THR145 | |
C | THR179 | |
C | ASN206 | |
C | ASN228 | |
E | GLN11 | |
E | GLU71 | |
E | SER140 | |
D | GLU71 | |
E | GLY144 | |
E | THR145 | |
E | THR179 | |
E | ASN206 | |
E | ASN228 | |
G | GLN11 | |
G | GLU71 | |
G | SER140 | |
G | GLY144 | |
G | THR145 | |
F | GLU71 | |
G | THR179 | |
G | ASN206 | |
G | ASN228 | |
I | GLN11 | |
I | GLU71 | |
I | SER140 | |
I | GLY144 | |
I | THR145 | |
I | THR179 | |
I | ASN206 | |
H | GLU71 | |
I | ASN228 | |
K | GLN11 | |
K | GLU71 | |
K | SER140 | |
K | GLY144 | |
K | THR145 | |
K | THR179 | |
K | ASN206 | |
K | ASN228 | |
M | GLN11 | |
J | GLU71 | |
M | GLU71 | |
M | SER140 | |
M | GLY144 | |
M | THR145 | |
M | THR179 | |
M | ASN206 | |
M | ASN228 | |
O | GLN11 | |
O | GLU71 | |
O | SER140 | |
L | GLU71 | |
O | GLY144 | |
O | THR145 | |
O | THR179 | |
O | ASN206 | |
O | ASN228 | |
Q | GLN11 | |
Q | GLU71 | |
Q | SER140 | |
Q | GLY144 | |
Q | THR145 | |
N | GLU71 | |
Q | THR179 | |
Q | ASN206 | |
Q | ASN228 | |
P | GLU71 | |
R | GLU71 |
site_id | SWS_FT_FI3 |
Number of Residues | 9 |
Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P99024 |
Chain | Residue | Details |
B | SER40 | |
D | SER40 | |
F | SER40 | |
H | SER40 | |
J | SER40 | |
L | SER40 | |
N | SER40 | |
P | SER40 | |
R | SER40 |
site_id | SWS_FT_FI4 |
Number of Residues | 9 |
Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P99024 |
Chain | Residue | Details |
B | LYS60 | |
D | LYS60 | |
F | LYS60 | |
H | LYS60 | |
J | LYS60 | |
L | LYS60 | |
N | LYS60 | |
P | LYS60 | |
R | LYS60 |
site_id | SWS_FT_FI5 |
Number of Residues | 9 |
Details | MOD_RES: Phosphoserine; by CDK1 => ECO:0000250|UniProtKB:Q13885 |
Chain | Residue | Details |
B | SER174 | |
D | SER174 | |
F | SER174 | |
H | SER174 | |
J | SER174 | |
L | SER174 | |
N | SER174 | |
P | SER174 | |
R | SER174 |
site_id | SWS_FT_FI6 |
Number of Residues | 18 |
Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P07437 |
Chain | Residue | Details |
B | THR287 | |
J | THR292 | |
L | THR287 | |
L | THR292 | |
N | THR287 | |
N | THR292 | |
P | THR287 | |
P | THR292 | |
R | THR287 | |
R | THR292 | |
B | THR292 | |
D | THR287 | |
D | THR292 | |
F | THR287 | |
F | THR292 | |
H | THR287 | |
H | THR292 | |
J | THR287 |
site_id | SWS_FT_FI7 |
Number of Residues | 9 |
Details | MOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:P07437 |
Chain | Residue | Details |
B | ARG320 | |
D | ARG320 | |
F | ARG320 | |
H | ARG320 | |
J | ARG320 | |
L | ARG320 | |
N | ARG320 | |
P | ARG320 | |
R | ARG320 |
site_id | SWS_FT_FI8 |
Number of Residues | 9 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P07437 |
Chain | Residue | Details |
B | LYS60 | |
D | LYS60 | |
F | LYS60 | |
H | LYS60 | |
J | LYS60 | |
L | LYS60 | |
N | LYS60 | |
P | LYS60 | |
R | LYS60 |
site_id | SWS_FT_FI9 |
Number of Residues | 18 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P07437 |
Chain | Residue | Details |
J | LYS326 | |
L | LYS326 | |
N | LYS326 | |
P | LYS326 | |
R | LYS326 | |
B | LYS326 | |
D | LYS326 | |
F | LYS326 | |
H | LYS326 |