Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5XX1

Crystal structure of Arginine decarboxylase (AdiA) from Salmonella typhimurium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006520	biological_process	amino acid metabolic process
A	0006527	biological_process	arginine catabolic process
A	0008792	molecular_function	arginine decarboxylase activity
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0030170	molecular_function	pyridoxal phosphate binding
B	0003824	molecular_function	catalytic activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006520	biological_process	amino acid metabolic process
B	0006527	biological_process	arginine catabolic process
B	0008792	molecular_function	arginine decarboxylase activity
B	0016829	molecular_function	lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	0030170	molecular_function	pyridoxal phosphate binding
C	0003824	molecular_function	catalytic activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006520	biological_process	amino acid metabolic process
C	0006527	biological_process	arginine catabolic process
C	0008792	molecular_function	arginine decarboxylase activity
C	0016829	molecular_function	lyase activity
C	0016831	molecular_function	carboxy-lyase activity
C	0030170	molecular_function	pyridoxal phosphate binding
D	0003824	molecular_function	catalytic activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006520	biological_process	amino acid metabolic process
D	0006527	biological_process	arginine catabolic process
D	0008792	molecular_function	arginine decarboxylase activity
D	0016829	molecular_function	lyase activity
D	0016831	molecular_function	carboxy-lyase activity
D	0030170	molecular_function	pyridoxal phosphate binding
E	0003824	molecular_function	catalytic activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006520	biological_process	amino acid metabolic process
E	0006527	biological_process	arginine catabolic process
E	0008792	molecular_function	arginine decarboxylase activity
E	0016829	molecular_function	lyase activity
E	0016831	molecular_function	carboxy-lyase activity
E	0030170	molecular_function	pyridoxal phosphate binding
F	0003824	molecular_function	catalytic activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006520	biological_process	amino acid metabolic process
F	0006527	biological_process	arginine catabolic process
F	0008792	molecular_function	arginine decarboxylase activity
F	0016829	molecular_function	lyase activity
F	0016831	molecular_function	carboxy-lyase activity
F	0030170	molecular_function	pyridoxal phosphate binding
G	0003824	molecular_function	catalytic activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006520	biological_process	amino acid metabolic process
G	0006527	biological_process	arginine catabolic process
G	0008792	molecular_function	arginine decarboxylase activity
G	0016829	molecular_function	lyase activity
G	0016831	molecular_function	carboxy-lyase activity
G	0030170	molecular_function	pyridoxal phosphate binding
H	0003824	molecular_function	catalytic activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006520	biological_process	amino acid metabolic process
H	0006527	biological_process	arginine catabolic process
H	0008792	molecular_function	arginine decarboxylase activity
H	0016829	molecular_function	lyase activity
H	0016831	molecular_function	carboxy-lyase activity
H	0030170	molecular_function	pyridoxal phosphate binding
I	0003824	molecular_function	catalytic activity
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006520	biological_process	amino acid metabolic process
I	0006527	biological_process	arginine catabolic process
I	0008792	molecular_function	arginine decarboxylase activity
I	0016829	molecular_function	lyase activity
I	0016831	molecular_function	carboxy-lyase activity
I	0030170	molecular_function	pyridoxal phosphate binding
J	0003824	molecular_function	catalytic activity
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006520	biological_process	amino acid metabolic process
J	0006527	biological_process	arginine catabolic process
J	0008792	molecular_function	arginine decarboxylase activity
J	0016829	molecular_function	lyase activity
J	0016831	molecular_function	carboxy-lyase activity
J	0030170	molecular_function	pyridoxal phosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue PO4 A 801

Chain	Residue
A	GLY230
J	SER423
A	THR231
A	SER232
A	HIS256
A	SER384
A	HIS386
A	LYS387
J	THR421
J	THR422

site_id	AC2
Number of Residues	9
Details	binding site for residue PO4 B 801

Chain	Residue
B	GLY230
B	THR231
B	SER232
B	HIS256
B	SER384
B	HIS386
I	THR421
I	THR422
I	SER423

site_id	AC3
Number of Residues	9
Details	binding site for residue PO4 C 801

Chain	Residue
C	GLY230
C	THR231
C	SER232
C	HIS256
C	SER384
C	HIS386
H	THR421
H	THR422
H	SER423

site_id	AC4
Number of Residues	10
Details	binding site for residue PO4 D 801

Chain	Residue
D	GLY230
D	THR231
D	SER232
D	HIS256
D	SER384
D	HIS386
D	LYS387
G	THR421
G	THR422
G	SER423

site_id	AC5
Number of Residues	10
Details	binding site for residue PO4 E 801

Chain	Residue
E	GLY230
E	THR231
E	SER232
E	HIS256
E	SER384
E	HIS386
E	LYS387
F	THR421
F	THR422
F	SER423

site_id	AC6
Number of Residues	9
Details	binding site for residue PO4 F 801

Chain	Residue
E	THR421
E	THR422
E	SER423
F	GLY230
F	THR231
F	SER232
F	SER384
F	HIS386
F	LYS387

site_id	AC7
Number of Residues	10
Details	binding site for residue PO4 G 801

Chain	Residue
D	THR421
D	THR422
D	SER423
G	GLY230
G	THR231
G	SER232
G	HIS256
G	SER384
G	HIS386
G	LYS387

site_id	AC8
Number of Residues	8
Details	binding site for residue PO4 H 801

Chain	Residue
C	THR421
C	THR422
C	SER423
H	GLY230
H	THR231
H	SER232
H	SER384
H	HIS386

site_id	AC9
Number of Residues	10
Details	binding site for residue PO4 I 801

Chain	Residue
B	THR421
B	THR422
B	SER423
I	GLY230
I	THR231
I	SER232
I	HIS256
I	SER384
I	HIS386
I	LYS387

site_id	AD1
Number of Residues	10
Details	binding site for residue PO4 J 801

Chain	Residue
A	THR421
A	THR422
A	SER423
J	GLY230
J	THR231
J	SER232
J	HIS256
J	SER384
J	HIS386
J	LYS387

Functional Information from PROSITE/UniProt

site_id	PS00703
Number of Residues	15
Details	OKR_DC_1 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. ThStHKllNAlSQAS

Chain	Residue	Details
A	THR382-SER396

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)