Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006508 | biological_process | proteolysis |
| B | 0007586 | biological_process | digestion |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | GLU60 |
| A | ASN62 |
| A | VAL65 |
| A | GLU70 |
| A | HOH403 |
| A | HOH492 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue MPD A 302 |
| Chain | Residue |
| A | CYS191 |
| A | ASN192 |
| A | GLY193 |
| B | SER158 |
| B | PRO161 |
| A | GLU123 |
| A | CYS124 |
| A | VAL190 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 300 |
| Chain | Residue |
| B | GLU60 |
| B | ASN62 |
| B | VAL65 |
| B | GLU70 |
| B | HOH404 |
| B | HOH458 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide ACE D 401 and THR D 402 |
| Chain | Residue |
| B | HIS48 |
| B | LEU89 |
| B | GLN182 |
| B | SER200 |
| B | TRP201 |
| B | GLY202 |
| B | HOH426 |
| D | ARG403 |
| D | HOH501 |
| D | HOH502 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL44-CYS49 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP179-VAL190 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS48 | |
| A | ASP92 | |
| A | SER185 | |
| B | HIS48 | |
| B | ASP92 | |
| B | SER185 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU60 | |
| A | ASN62 | |
| A | VAL65 | |
| A | GLU70 | |
| B | GLU60 | |
| B | ASN62 | |
| B | VAL65 | |
| B | GLU70 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Required for specificity => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP179 | |
| B | ASP179 | |
