Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004353 | molecular_function | glutamate dehydrogenase [NAD(P)+] activity |
| A | 0004354 | molecular_function | glutamate dehydrogenase (NADP+) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006537 | biological_process | glutamate biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016639 | molecular_function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 41 |
| Details | binding site for residue NAP A 501 |
| Chain | Residue |
| A | ARG82 |
| A | GLY230 |
| A | ASN231 |
| A | VAL232 |
| A | SER251 |
| A | ASP252 |
| A | SER253 |
| A | LYS277 |
| A | GLN282 |
| A | SER319 |
| A | ALA320 |
| A | HIS84 |
| A | THR321 |
| A | GLY344 |
| A | SER345 |
| A | ASN346 |
| A | ASN379 |
| A | 8GL502 |
| A | 2IT503 |
| A | GOL504 |
| A | GOL516 |
| A | GOL547 |
| A | LYS122 |
| A | HOH602 |
| A | HOH648 |
| A | HOH657 |
| A | HOH671 |
| A | HOH718 |
| A | HOH738 |
| A | HOH755 |
| A | HOH762 |
| A | HOH812 |
| A | HOH863 |
| A | ASP154 |
| A | HOH866 |
| A | HOH895 |
| A | ILE155 |
| A | GLY156 |
| A | ARG193 |
| A | THR197 |
| A | SER229 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | GLY153 |
| A | ASP154 |
| A | GLY182 |
| A | ARG193 |
| A | NAP501 |
| A | GOL531 |
| A | HOH604 |
| A | HOH648 |
| A | HOH758 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | LYS142 |
| A | HOH622 |
| A | HOH622 |
| A | HOH665 |
| A | HOH665 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 506 |
| Chain | Residue |
| A | LEU105 |
| A | GLY107 |
| A | ASP414 |
| A | CYS415 |
| A | ASN418 |
| A | LYS448 |
| A | GOL549 |
| A | HOH638 |
| A | HOH917 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 507 |
| Chain | Residue |
| A | TYR199 |
| A | TYR203 |
| A | LYS239 |
| A | GLU242 |
| A | SER401 |
| A | ASP405 |
| A | HOH619 |
| A | HOH634 |
| A | HOH649 |
| A | HOH890 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 508 |
| Chain | Residue |
| A | PRO43 |
| A | GLN48 |
| A | PHE49 |
| A | ARG50 |
| A | ARG64 |
| A | LYS93 |
| A | HOH734 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 509 |
| Chain | Residue |
| A | ALA304 |
| A | ARG305 |
| A | PRO306 |
| A | TRP307 |
| A | VAL308 |
| A | GLU329 |
| A | HOH615 |
| A | HOH714 |
| A | HOH931 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 510 |
| Chain | Residue |
| A | SER72 |
| A | PRO76 |
| A | TYR77 |
| A | THR148 |
| A | ARG170 |
| A | ASN174 |
| A | GLN175 |
| A | TRP176 |
| A | HOH672 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 511 |
| Chain | Residue |
| A | GLU217 |
| A | LYS220 |
| A | GLY221 |
| A | LYS222 |
| A | HOH660 |
| A | HOH694 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 512 |
| Chain | Residue |
| A | THR447 |
| A | LYS448 |
| A | GOL534 |
| A | HOH654 |
| A | HOH698 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 513 |
| Chain | Residue |
| A | GLN12 |
| A | THR350 |
| A | GLN351 |
| A | GLU352 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 514 |
| Chain | Residue |
| A | GLY107 |
| A | LEU108 |
| A | ASN109 |
| A | SER186 |
| A | LYS448 |
| A | HOH603 |
| A | HOH605 |
| A | HOH638 |
| A | HOH727 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 515 |
| Chain | Residue |
| A | ASP252 |
| A | SER253 |
| A | GLY303 |
| A | ALA304 |
| A | GOL516 |
| A | HOH628 |
| A | HOH785 |
| A | HOH904 |
| site_id | AD5 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 516 |
| Chain | Residue |
| A | ARG305 |
| A | THR321 |
| A | GLN322 |
| A | ASN323 |
| A | NAP501 |
| A | GOL515 |
| A | GOL547 |
| A | HOH733 |
| A | HOH785 |
| A | HOH853 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 517 |
| Chain | Residue |
| A | GLU403 |
| A | ARG407 |
| A | GOL527 |
| A | HOH627 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 518 |
| Chain | Residue |
| A | PHE10 |
| A | TYR14 |
| A | SER41 |
| A | HOH606 |
| A | HOH642 |
| A | HOH724 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 519 |
| Chain | Residue |
| A | LYS35 |
| A | VAL60 |
| A | VAL62 |
| A | HOH620 |
| A | HOH728 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 520 |
| Chain | Residue |
| A | LYS183 |
| A | GLY185 |
| A | SER190 |
| A | HOH609 |
| A | HOH613 |
| A | HOH704 |
| A | HOH1002 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 521 |
| Chain | Residue |
| A | LEU191 |
| A | SER398 |
| A | TRP399 |
| A | THR400 |
| A | GOL527 |
| A | HOH608 |
| A | HOH896 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 522 |
| Chain | Residue |
| A | GLY123 |
| A | LYS124 |
| A | GLU279 |
| A | ARG280 |
| A | GOL544 |
| A | HOH902 |
| A | HOH929 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 523 |
| Chain | Residue |
| A | ASN3 |
| A | PRO8 |
| A | GLU9 |
| A | ASN88 |
| A | SER90 |
| A | HOH794 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 524 |
| Chain | Residue |
| A | LYS312 |
| A | LYS312 |
| A | GOL537 |
| A | GOL537 |
| A | HOH726 |
| site_id | AE5 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 525 |
| Chain | Residue |
| A | GLY145 |
| A | ALA146 |
| A | ASP147 |
| A | THR148 |
| A | TYR169 |
| A | ARG173 |
| A | GLN175 |
| A | GLN175 |
| A | GLU177 |
| A | HOH610 |
| A | HOH870 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 526 |
| Chain | Residue |
| A | PRO8 |
| A | GLU11 |
| A | LYS15 |
| A | HOH614 |
| A | HOH770 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 527 |
| Chain | Residue |
| A | SER398 |
| A | GLU403 |
| A | ARG407 |
| A | GOL517 |
| A | GOL521 |
| A | GOL530 |
| A | HOH616 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 528 |
| Chain | Residue |
| A | PHE292 |
| A | SER293 |
| A | PHE298 |
| A | TYR300 |
| A | HOH673 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 529 |
| Chain | Residue |
| A | THR428 |
| A | PRO429 |
| A | HOH711 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 530 |
| Chain | Residue |
| A | LEU108 |
| A | SER398 |
| A | ARG407 |
| A | GOL527 |
| A | HOH612 |
| site_id | AF2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 531 |
| Chain | Residue |
| A | THR158 |
| A | GLY159 |
| A | PRO194 |
| A | GOL504 |
| A | HOH604 |
| A | HOH617 |
| A | HOH758 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 532 |
| Chain | Residue |
| A | TRP53 |
| A | GLN61 |
| A | VAL62 |
| A | ASN63 |
| A | HOH620 |
| A | HOH643 |
| A | HOH647 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 533 |
| Chain | Residue |
| A | LYS15 |
| A | SER19 |
| A | GLN351 |
| A | ASP355 |
| A | HOH659 |
| A | HOH706 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 534 |
| Chain | Residue |
| A | GOL512 |
| A | GOL541 |
| A | HOH658 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 535 |
| Chain | Residue |
| A | ASN418 |
| A | THR422 |
| A | TYR426 |
| A | THR447 |
| A | GOL548 |
| A | HOH740 |
| site_id | AF7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 536 |
| Chain | Residue |
| A | HIS207 |
| A | ALA210 |
| A | GOL550 |
| A | GOL551 |
| A | HOH623 |
| A | HOH666 |
| A | HOH766 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 537 |
| Chain | Residue |
| A | GLU262 |
| A | GLY311 |
| A | LYS312 |
| A | GOL524 |
| A | GOL524 |
| site_id | AF9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 538 |
| Chain | Residue |
| A | ALA212 |
| A | ASN214 |
| A | GLY366 |
| A | ALA367 |
| A | HOH630 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 539 |
| Chain | Residue |
| A | GLY263 |
| A | SER264 |
| A | ASN296 |
| A | LYS297 |
| A | GOL543 |
| A | HOH601 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 540 |
| Chain | Residue |
| A | GLN234 |
| A | TYR235 |
| A | GLU271 |
| A | HOH661 |
| site_id | AG3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 541 |
| Chain | Residue |
| A | ALA451 |
| A | ASP455 |
| A | GOL534 |
| A | HOH658 |
| A | HOH695 |
| A | HOH743 |
| A | HOH824 |
| site_id | AG4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 542 |
| Chain | Residue |
| A | LYS142 |
| A | HOH810 |
| A | HOH865 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 543 |
| Chain | Residue |
| A | GLU262 |
| A | ALA295 |
| A | GOL539 |
| A | HOH739 |
| site_id | AG6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 544 |
| Chain | Residue |
| A | GLY123 |
| A | SER125 |
| A | GOL522 |
| A | HOH685 |
| A | HOH716 |
| site_id | AG7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 545 |
| Chain | Residue |
| A | ARG361 |
| A | PRO429 |
| A | HOH669 |
| A | HOH722 |
| A | HOH772 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 546 |
| Chain | Residue |
| A | TYR14 |
| A | GLU22 |
| A | ARG34 |
| A | HOH691 |
| site_id | AG9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 547 |
| Chain | Residue |
| A | THR321 |
| A | GLN322 |
| A | NAP501 |
| A | GOL516 |
| A | HOH710 |
| site_id | AH1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 548 |
| Chain | Residue |
| A | ASN418 |
| A | GLU421 |
| A | THR422 |
| A | GLU425 |
| A | GOL535 |
| A | GOL549 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 549 |
| Chain | Residue |
| A | ASP414 |
| A | GLU421 |
| A | GOL506 |
| A | GOL548 |
| A | HOH621 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 550 |
| Chain | Residue |
| A | HIS207 |
| A | HIS211 |
| A | PHE416 |
| A | GOL536 |
| A | HOH611 |
| site_id | AH4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 551 |
| Chain | Residue |
| A | ALA210 |
| A | GLY215 |
| A | GLU217 |
| A | GOL536 |
| A | HOH626 |
| A | HOH631 |
| site_id | AH5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 552 |
| Chain | Residue |
| A | LEU4 |
| A | HIS6 |
| A | GLU11 |
| site_id | AH6 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 553 |
| Chain | Residue |
| A | THR276 |
| A | GLU279 |
| A | LYS281 |
| A | ILE286 |
| A | HOH640 |
| site_id | AH7 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
| site_id | AH8 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
| site_id | AH9 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
| site_id | AI1 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
| site_id | AI2 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
| site_id | AI3 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
| site_id | AI4 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
| site_id | AI5 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
| site_id | AI6 |
| Number of Residues | 16 |
| Details | binding site for residues 8GL A 502 and 2IT A 503 |
| Chain | Residue |
| A | LYS78 |
| A | GLY79 |
| A | GLY80 |
| A | GLN99 |
| A | LYS102 |
| A | LYS114 |
| A | ALA152 |
| A | GLY153 |
| A | ASP154 |
| A | THR181 |
| A | ARG193 |
| A | ASN346 |
| A | VAL383 |
| A | SER386 |
| A | NAP501 |
| A | HOH676 |
Functional Information from PROSITE/UniProt
| site_id | PS00074 |
| Number of Residues | 14 |
| Details | GLFV_DEHYDROGENASE Glu / Leu / Phe / Val dehydrogenases active site. LnmGGGKgGsdfDP |
| Chain | Residue | Details |
| A | LEU108-PRO121 | |
