5XVZ

CATPO mutant - H246W

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004096	molecular_function	catalase activity
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0020037	molecular_function	heme binding
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0098869	biological_process	cellular oxidant detoxification
B	0004096	molecular_function	catalase activity
B	0005829	cellular_component	cytosol
B	0006979	biological_process	response to oxidative stress
B	0020037	molecular_function	heme binding
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0098869	biological_process	cellular oxidant detoxification
C	0004096	molecular_function	catalase activity
C	0005829	cellular_component	cytosol
C	0006979	biological_process	response to oxidative stress
C	0020037	molecular_function	heme binding
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0098869	biological_process	cellular oxidant detoxification
D	0004096	molecular_function	catalase activity
D	0005829	cellular_component	cytosol
D	0006979	biological_process	response to oxidative stress
D	0020037	molecular_function	heme binding
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue HDD A 701

Chain	Residue
A	ARG79
A	PHE168
A	VAL228
A	HIS229
A	PHE345
A	LEU361
A	ARG365
A	SER368
A	TYR369
A	THR372
A	GLN373
A	VAL81
A	ARG376
A	HOH878
A	HOH890
A	HIS82
A	ARG119
A	GLY138
A	VAL153
A	GLY154
A	ASN155
A	PHE160

---

site_id	AC2
Number of Residues	3
Details	binding site for residue CA A 702

Chain	Residue
A	HIS190
A	ASP191
A	SER192

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CA A 703

Chain	Residue
A	THR437
A	HOH1233
B	ARG449

---

site_id	AC4
Number of Residues	3
Details	binding site for residue CA A 704

Chain	Residue
A	ARG449
B	THR437
B	HOH1233

---

site_id	AC5
Number of Residues	9
Details	binding site for residue 1PE A 705

Chain	Residue
A	ALA25
A	TYR26
A	GLU27
A	HOH852
A	HOH953
D	ALA25
D	TYR26
D	MET389
D	1PE704

---

site_id	AC6
Number of Residues	22
Details	binding site for residue HDD B 701

Chain	Residue
B	ARG79
B	VAL81
B	HIS82
B	ARG119
B	GLY138
B	VAL153
B	GLY154
B	ASN155
B	PHE160
B	PHE168
B	VAL228
B	HIS229
B	PHE345
B	LEU361
B	ARG365
B	SER368
B	TYR369
B	THR372
B	GLN373
B	ARG376
B	HOH818
B	HOH887

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CA B 702

Chain	Residue
B	ARG178
B	HIS190
B	ASP191
B	SER192
B	HOH1218

---

site_id	AC8
Number of Residues	3
Details	binding site for residue CA B 703

Chain	Residue
B	GLY213
B	SER255
B	HOH1117

---

site_id	AC9
Number of Residues	6
Details	binding site for residue CA B 704

Chain	Residue
B	HOH1227
B	HOH1256
C	HOH861
C	HOH1244
C	HOH1270
D	HOH866

---

site_id	AD1
Number of Residues	4
Details	binding site for residue 1PE B 705

Chain	Residue
C	SER94
C	TYR95
C	GLY111
C	GLN113

---

site_id	AD2
Number of Residues	23
Details	binding site for residue HDD C 701

Chain	Residue
C	ARG376
C	HOH872
C	HOH1040
C	HOH1184
C	ARG79
C	VAL81
C	HIS82
C	ARG119
C	GLY138
C	VAL153
C	GLY154
C	ASN155
C	PHE160
C	PHE168
C	VAL228
C	HIS229
C	PHE345
C	LEU361
C	ARG365
C	SER368
C	TYR369
C	THR372
C	GLN373

---

site_id	AD3
Number of Residues	4
Details	binding site for residue CA C 702

Chain	Residue
C	HIS190
C	ASP191
C	SER192
D	HOH1165

---

site_id	AD4
Number of Residues	2
Details	binding site for residue CA C 703

Chain	Residue
C	SER255
C	HOH1169

---

site_id	AD5
Number of Residues	24
Details	binding site for residue HDD D 701

Chain	Residue
D	ARG79
D	VAL81
D	HIS82
D	ARG119
D	GLY138
D	VAL153
D	GLY154
D	ASN155
D	PHE160
D	ALA165
D	PHE168
D	VAL228
D	HIS229
D	PHE345
D	LEU361
D	ARG365
D	SER368
D	TYR369
D	THR372
D	GLN373
D	ARG376
D	HOH824
D	HOH1039
D	HOH1149

---

site_id	AD6
Number of Residues	6
Details	binding site for residue CA D 702

Chain	Residue
D	ARG178
D	HIS190
D	ASP191
D	SER192
D	HOH1140
D	HOH1203

---

site_id	AD7
Number of Residues	2
Details	binding site for residue CA D 703

Chain	Residue
D	SER255
D	HOH1129

---

site_id	AD8
Number of Residues	11
Details	binding site for residue 1PE D 704

Chain	Residue
A	VAL28
A	ASP29
A	ASP30
A	1PE705
D	PRO390
D	ARG391
D	VAL392
D	PRO393
D	ILE394
D	HIS395
D	HOH1151

---

Functional Information from PROSITE/UniProt

site_id	PS00437
Number of Residues	9
Details	CATALASE_1 Catalase proximal heme-ligand signature. RLFSYlDTQ

Chain	Residue	Details
A	ARG365-GLN373

---

site_id	PS00438
Number of Residues	17
Details	CATALASE_2 Catalase proximal active site signature. FdHervpERavHarGAG

Chain	Residue	Details
A	PHE71-GLY87

---

site_id	PS00674
Number of Residues	20
Details	AAA AAA-protein family signature. VgILaTTSessaLDqAAqlR

Chain	Residue	Details
A	VAL552-ARG571

---