5XT6
A sulfur-transferring catalytic intermediate of SufS-SufU complex from Bacillus subtilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006534 | biological_process | cysteine metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0031071 | molecular_function | cysteine desulfurase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006534 | biological_process | cysteine metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0031071 | molecular_function | cysteine desulfurase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006879 | biological_process | intracellular iron ion homeostasis |
| C | 0008198 | molecular_function | ferrous iron binding |
| C | 0016226 | biological_process | iron-sulfur cluster assembly |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051536 | molecular_function | iron-sulfur cluster binding |
| C | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006879 | biological_process | intracellular iron ion homeostasis |
| D | 0008198 | molecular_function | ferrous iron binding |
| D | 0016226 | biological_process | iron-sulfur cluster assembly |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 201 |
| Chain | Residue |
| B | HIS342 |
| D | ASP43 |
| D | CYS66 |
| D | CYS128 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue PDA A 501 |
| Chain | Residue |
| A | ASN173 |
| A | ASP198 |
| A | ALA200 |
| A | GLN201 |
| A | SER221 |
| A | HIS223 |
| A | LYS224 |
| A | ARG356 |
| A | HIS360 |
| A | ARG376 |
| B | GLY274 |
| B | THR275 |
| A | ALA28 |
| A | ALA29 |
| A | THR92 |
| A | THR93 |
| A | HIS121 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue PDA B 501 |
| Chain | Residue |
| A | ARG54 |
| A | GLY274 |
| A | THR275 |
| B | ALA28 |
| B | THR92 |
| B | THR93 |
| B | HIS121 |
| B | ASN173 |
| B | ASP198 |
| B | ALA200 |
| B | GLN201 |
| B | SER221 |
| B | HIS223 |
| B | LYS224 |
| B | ARG356 |
| B | ARG376 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 201 |
| Chain | Residue |
| A | HIS342 |
| C | ASP43 |
| C | CYS66 |
| C | CYS128 |
Functional Information from PROSITE/UniProt
| site_id | PS00595 |
| Number of Residues | 20 |
| Details | AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. CDFFalSSHKmcgpt.GvGvL |
| Chain | Residue | Details |
| A | CYS215-LEU234 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29235855","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2005","submissionDatabase":"PDB data bank","title":"Solution NMR structure of Zn-ligated Fe-S cluster assembly scaffold protein SufU From Bacillus subtilis.","authors":["Kornhaber G.J.","Swapna G.V.T.","Ramelot T.A.","Cort J.R.","Aramini J.M.","Kennedy M.A.","Montelione G.T."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2004","submissionDatabase":"PDB data bank","title":"Solution structure of iron-sulfur cluster assembly protein IscU from Bacillus subtilis, with zinc bound at the active site. Northeast Structural Genomics Consortium Target SR17.","authors":["Kornhaber G.J.","Swapna G.V.T.","Ramelot T.A.","Cort J.R.","Kennedy M.A.","Montelione G.T."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Cysteine persulfide intermediate","evidences":[{"source":"PubMed","id":"27382962","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31587510","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"31587510","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5J8Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
