5XSY
Structure of the Nav1.4-beta1 complex from electric eel
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001518 | cellular_component | voltage-gated sodium channel complex |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005248 | molecular_function | voltage-gated sodium channel activity |
| A | 0005261 | molecular_function | monoatomic cation channel activity |
| A | 0005272 | molecular_function | sodium channel activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006814 | biological_process | sodium ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0019228 | biological_process | neuronal action potential |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0034702 | cellular_component | monoatomic ion channel complex |
| A | 0035725 | biological_process | sodium ion transmembrane transport |
| A | 0042391 | biological_process | regulation of membrane potential |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0086010 | biological_process | membrane depolarization during action potential |
| B | 0001518 | cellular_component | voltage-gated sodium channel complex |
| B | 0006814 | biological_process | sodium ion transport |
| B | 0017080 | molecular_function | sodium channel regulator activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S1 of repeat I"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 281 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=S2 of repeat I"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 141 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S3 of repeat I"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S5 of repeat I"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 87 |
| Details | Intramembrane: {"description":"Pore-forming","evidences":[{"source":"UniProtKB","id":"D0E0C2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=S6 of repeat I"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S1 of repeat II"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S2 of repeat II"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 17 |
| Details | Transmembrane: {"description":"Helical; Name=S3 of repeat II"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S5 of repeat II"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=S6 of repeat II"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S1 of repeat III"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S2 of repeat III"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S5 of repeat III"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S6 of repeat III"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S1 of repeat IV"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=S2 of repeat IV"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 17 |
| Details | Transmembrane: {"description":"Helical; Name=S3 of repeat IV"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Voltage-sensor; Name=S4 of repeat IV"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=S5 of repeat IV"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI23 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=S6 of repeat IV"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI24 |
| Number of Residues | 57 |
| Details | Region: {"description":"Non-homologous region of repeat I"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI25 |
| Number of Residues | 22 |
| Details | Region: {"description":"Non-homologous region of repeat III"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI26 |
| Number of Residues | 15 |
| Details | Region: {"description":"Non-homologous region of repeat IV"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI27 |
| Number of Residues | 6 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
