5XOH
Crystal structure of bergaptol o-methyltransferase complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0009753 | biological_process | response to jasmonic acid |
| A | 0009805 | biological_process | coumarin biosynthetic process |
| A | 0019438 | biological_process | obsolete aromatic compound biosynthetic process |
| A | 0030752 | molecular_function | 5-hydroxyfuranocoumarin 5-O-methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue SAH A 401 |
| Chain | Residue |
| A | PHE158 |
| A | ILE262 |
| A | TRP266 |
| A | 8B6402 |
| A | HOH501 |
| A | HOH539 |
| A | HOH543 |
| A | MET175 |
| A | SER179 |
| A | GLY203 |
| A | ASP226 |
| A | LEU227 |
| A | ASP246 |
| A | MET247 |
| A | LYS260 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue 8B6 A 402 |
| Chain | Residue |
| A | LEU122 |
| A | HIS126 |
| A | ILE157 |
| A | PHE158 |
| A | MET175 |
| A | TRP261 |
| A | HIS264 |
| A | SER265 |
| A | LEU312 |
| A | MET316 |
| A | SAH401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01020 |
| Chain | Residue | Details |
| A | HIS264 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31666994, ECO:0007744|PDB:5XOH |
| Chain | Residue | Details |
| A | HIS126 | |
| A | SER179 | |
| A | GLY203 | |
| A | ASP226 | |
| A | ASP246 | |
| A | LYS260 | |
| A | HIS264 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Determines the catalytic selectivity of hydroxyl groups in esculetin => ECO:0000250|UniProtKB:A0A4P8DY91 |
| Chain | Residue | Details |
| A | HIS126 |
