5XMT
Plasmodium vivax SHMT bound with PLP-glycine and GS380
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
A | 0006730 | biological_process | one-carbon metabolic process |
A | 0016740 | molecular_function | transferase activity |
A | 0019264 | biological_process | glycine biosynthetic process from serine |
A | 0030170 | molecular_function | pyridoxal phosphate binding |
A | 0035999 | biological_process | tetrahydrofolate interconversion |
B | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
B | 0006730 | biological_process | one-carbon metabolic process |
B | 0016740 | molecular_function | transferase activity |
B | 0019264 | biological_process | glycine biosynthetic process from serine |
B | 0030170 | molecular_function | pyridoxal phosphate binding |
B | 0035999 | biological_process | tetrahydrofolate interconversion |
C | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
C | 0006730 | biological_process | one-carbon metabolic process |
C | 0016740 | molecular_function | transferase activity |
C | 0019264 | biological_process | glycine biosynthetic process from serine |
C | 0030170 | molecular_function | pyridoxal phosphate binding |
C | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 21 |
Details | binding site for residue PLG A 501 |
Chain | Residue |
A | SER34 |
A | HIS211 |
A | THR234 |
A | HIS236 |
A | LYS237 |
A | ARG371 |
A | HOH628 |
B | TYR54 |
B | TYR64 |
B | GLY271 |
B | GLY272 |
A | SER100 |
B | HOH645 |
B | HOH652 |
A | GLY101 |
A | SER102 |
A | HIS129 |
A | TYR182 |
A | THR183 |
A | ASP208 |
A | SER210 |
site_id | AC2 |
Number of Residues | 11 |
Details | binding site for residue 8B0 A 502 |
Chain | Residue |
A | GLU56 |
A | TYR63 |
A | TYR64 |
B | LEU124 |
B | GLY128 |
B | HIS129 |
B | LEU130 |
B | THR183 |
B | ASN354 |
B | LYS355 |
B | CYS364 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue CL A 503 |
Chain | Residue |
A | ASN276 |
A | LYS277 |
B | ASN276 |
B | LYS277 |
site_id | AC4 |
Number of Residues | 21 |
Details | binding site for residue PLG B 501 |
Chain | Residue |
A | TYR54 |
A | TYR64 |
A | GLY271 |
A | GLY272 |
B | SER34 |
B | SER100 |
B | GLY101 |
B | SER102 |
B | HIS129 |
B | TYR182 |
B | THR183 |
B | ASP208 |
B | SER210 |
B | HIS211 |
B | THR234 |
B | HIS236 |
B | LYS237 |
B | ARG371 |
B | HOH638 |
B | HOH661 |
B | HOH664 |
site_id | AC5 |
Number of Residues | 10 |
Details | binding site for residue 8B0 B 502 |
Chain | Residue |
A | LEU124 |
A | GLY128 |
A | HIS129 |
A | LEU130 |
A | THR183 |
A | LYS355 |
A | CYS364 |
B | GLU56 |
B | TYR63 |
B | TYR64 |
site_id | AC6 |
Number of Residues | 21 |
Details | binding site for residue PLG C 501 |
Chain | Residue |
C | SER34 |
C | TYR54 |
C | TYR64 |
C | SER100 |
C | GLY101 |
C | SER102 |
C | HIS129 |
C | TYR182 |
C | THR183 |
C | ASP208 |
C | SER210 |
C | HIS211 |
C | THR234 |
C | HIS236 |
C | LYS237 |
C | GLY271 |
C | GLY272 |
C | ARG371 |
C | HOH611 |
C | HOH652 |
C | HOH673 |
site_id | AC7 |
Number of Residues | 11 |
Details | binding site for residue 8B0 C 502 |
Chain | Residue |
C | GLU56 |
C | TYR63 |
C | TYR64 |
C | LEU124 |
C | GLY128 |
C | HIS129 |
C | LEU130 |
C | THR183 |
C | LYS355 |
C | THR357 |
C | CYS364 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue CL C 503 |
Chain | Residue |
C | ASN276 |
C | ASN276 |
C | LYS277 |
C | LYS277 |