5XLY
Crystal structure of CheR1 in complex with c-di-GMP-bound MapZ
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008276 | molecular_function | protein methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0008983 | molecular_function | protein-glutamate O-methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0035438 | molecular_function | cyclic-di-GMP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue C2E B 201 |
| Chain | Residue |
| A | PRO181 |
| B | ARG13 |
| B | TRP77 |
| B | ARG79 |
| B | C2E202 |
| B | HOH331 |
| B | HOH345 |
| B | HOH350 |
| B | HOH372 |
| B | HOH374 |
| B | HOH384 |
| A | GLU195 |
| B | HOH396 |
| B | HOH400 |
| B | HOH401 |
| B | HOH402 |
| B | HOH409 |
| B | HOH410 |
| B | HOH424 |
| A | ARG197 |
| A | SER207 |
| A | HOH389 |
| B | GLN4 |
| B | HIS5 |
| B | GLU7 |
| B | ARG9 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | binding site for residue C2E B 202 |
| Chain | Residue |
| B | GLN4 |
| B | HIS5 |
| B | GLU7 |
| B | ARG9 |
| B | ARG10 |
| B | ARG13 |
| B | ASP35 |
| B | VAL36 |
| B | SER37 |
| B | HIS39 |
| B | GLY40 |
| B | ILE41 |
| B | LEU42 |
| B | TRP77 |
| B | PHE85 |
| B | GLU86 |
| B | C2E201 |
| B | HOH319 |
| B | HOH330 |
| B | HOH331 |
| B | HOH380 |
| B | HOH384 |
| B | HOH392 |
| B | HOH415 |
| B | HOH419 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 96 |
| Details | Domain: {"description":"PilZ","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Motif: {"description":"RXXXR motif; surrounds the surface of the c-di-GMP binding site","evidences":[{"source":"PubMed","id":"21280119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21310957","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Motif: {"description":"DXSXXG motif; surrounds the surface of the c-di-GMP binding site","evidences":[{"source":"PubMed","id":"21280119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21310957","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21310957","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for c-di-GMP binding"} |
| Chain | Residue | Details |
