5XJ5

Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the monoacylglycerol form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0006644	biological_process	phospholipid metabolic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0016740	molecular_function	transferase activity
A	0043772	molecular_function	acyl-phosphate glycerol-3-phosphate acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue SO4 A 301

Chain	Residue
A	SER35
A	HOH444
A	ASN37
A	THR41
A	ASN42
A	ARG45
A	LYS104
A	HOH416
A	HOH417
A	HOH425

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 302

Chain	Residue
A	HIS190
A	HIS190
A	ARG191
A	HOH401
A	HOH418

---

site_id	AC3
Number of Residues	13
Details	binding site for residue SO4 A 303

Chain	Residue
A	GLY39
A	ALA40
A	HIS92
A	GLY103
A	LYS104
A	GLY105
A	VAL106
A	ALA107
A	78M311
A	HOH428
A	HOH438
A	HOH440
A	HOH456

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 A 304

Chain	Residue
A	TYR94
A	TYR175
A	ARG176
A	ARG178
A	78M316
A	HOH406

---

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 A 305

Chain	Residue
A	ARG45
A	HIS190
A	HOH405
A	HOH435
A	HOH462

---

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 A 306

Chain	Residue
A	ALA156
A	TYR158

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 A 307

Chain	Residue
A	GLY48
A	LYS49
A	LYS50
A	HOH407
A	HOH414

---

site_id	AC8
Number of Residues	9
Details	binding site for residue 78M A 308

Chain	Residue
A	FME0
A	VAL7
A	TRP79
A	GLY130
A	ILE131
A	LEU133
A	TRP134
A	78M319
A	HOH448

---

site_id	AC9
Number of Residues	7
Details	binding site for residue 78M A 309

Chain	Residue
A	TYR137
A	ILE143
A	SER148
A	LEU184
A	LEU185
A	78M319
A	HOH409

---

site_id	AD1
Number of Residues	9
Details	binding site for residue 78M A 310

Chain	Residue
A	TYR11
A	TYR94
A	PHE100
A	LYS101
A	PHE152
A	VAL155
A	ALA156
A	78M316
A	78M318

---

site_id	AD2
Number of Residues	17
Details	binding site for residue 78M A 311

Chain	Residue
A	ALA40
A	THR41
A	PHE56
A	LEU110
A	VAL113
A	SER124
A	TRP128
A	ALA145
A	THR146
A	PHE150
A	ALA166
A	SO4303
A	78M321
A	PGE323
A	HOH416
A	HOH420
A	HOH438

---

site_id	AD3
Number of Residues	5
Details	binding site for residue 78M A 312

Chain	Residue
A	FME0
A	SER2
A	SER73
A	78M320
A	GLY324

---

site_id	AD4
Number of Residues	5
Details	binding site for residue 78M A 313

Chain	Residue
A	FME0
A	GLY1
A	LEU4
A	LYS135
A	78M317

---

site_id	AD5
Number of Residues	9
Details	binding site for residue 78M A 314

Chain	Residue
A	LYS24
A	LEU25
A	LYS50
A	LEU54
A	PHE57
A	78M315
A	78M320
A	HOH403
A	VAL21

---

site_id	AD6
Number of Residues	8
Details	binding site for residue 78M A 315

Chain	Residue
A	GLU20
A	LYS24
A	ASP29
A	ARG31
A	PHE97
A	PHE98
A	78M314
A	78M317

---

site_id	AD7
Number of Residues	11
Details	binding site for residue 78M A 316

Chain	Residue
A	TYR94
A	PHE114
A	SER117
A	PRO118
A	SER119
A	TYR158
A	TYR175
A	SO4304
A	78M310
A	78M322
A	HOH408

---

site_id	AD8
Number of Residues	8
Details	binding site for residue 78M A 317

Chain	Residue
A	VAL96
A	PHE97
A	PHE98
A	GLY99
A	LYS101
A	78M313
A	78M315
A	78M318

---

site_id	AD9
Number of Residues	6
Details	binding site for residue 78M A 318

Chain	Residue
A	PHE100
A	PHE154
A	VAL155
A	GLY157
A	78M310
A	78M317

---

site_id	AE1
Number of Residues	3
Details	binding site for residue 78M A 319

Chain	Residue
A	SER148
A	78M308
A	78M309

---

site_id	AE2
Number of Residues	8
Details	binding site for residue 78M A 320

Chain	Residue
A	LEU13
A	LEU61
A	ILE65
A	LEU68
A	LYS72
A	SER73
A	78M312
A	78M314

---

site_id	AE3
Number of Residues	9
Details	binding site for residue 78M A 321

Chain	Residue
A	LYS49
A	PHE56
A	PHE60
A	PHE125
A	TRP128
A	LEU129
A	78M311
A	78M322
A	PGE323

---

site_id	AE4
Number of Residues	6
Details	binding site for residue 78M A 322

Chain	Residue
A	TRP79
A	PHE125
A	LEU133
A	ARG136
A	78M316
A	78M321

---

site_id	AE5
Number of Residues	7
Details	binding site for residue PGE A 323

Chain	Residue
A	THR44
A	LYS49
A	VAL53
A	TRP128
A	PHE132
A	78M311
A	78M321

---

site_id	AE6
Number of Residues	4
Details	binding site for residue GLY A 324

Chain	Residue
A	LYS72
A	SER73
A	GLY75
A	78M312

---

site_id	AE7
Number of Residues	9
Details	binding site for Di-peptide FME A 0 and GLY A 1

Chain	Residue
A	SER2
A	ALA3
A	LEU4
A	PHE5
A	TRP134
A	LYS135
A	78M308
A	78M312
A	78M313

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	100
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"HAMAP-Rule","id":"MF_01043","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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