5XGO

The Ferritin E-Domain: Toward Understanding Its Role in Protein Cage Assembly Through the Crystal Structure of a Maxi-/Mini-Ferritin Chimera

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006950	biological_process	response to stress
A	0008199	molecular_function	ferric iron binding
A	0009295	cellular_component	nucleoid
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016722	molecular_function	oxidoreductase activity, acting on metal ions
A	0030261	biological_process	chromosome condensation
A	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
A	0042594	biological_process	response to starvation
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	1990084	cellular_component	DnaA-Dps complex
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006950	biological_process	response to stress
B	0008199	molecular_function	ferric iron binding
B	0009295	cellular_component	nucleoid
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0016722	molecular_function	oxidoreductase activity, acting on metal ions
B	0030261	biological_process	chromosome condensation
B	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
B	0042594	biological_process	response to starvation
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	1990084	cellular_component	DnaA-Dps complex
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006950	biological_process	response to stress
C	0008199	molecular_function	ferric iron binding
C	0009295	cellular_component	nucleoid
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016722	molecular_function	oxidoreductase activity, acting on metal ions
C	0030261	biological_process	chromosome condensation
C	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
C	0042594	biological_process	response to starvation
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	1990084	cellular_component	DnaA-Dps complex
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006950	biological_process	response to stress
D	0008199	molecular_function	ferric iron binding
D	0009295	cellular_component	nucleoid
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0016722	molecular_function	oxidoreductase activity, acting on metal ions
D	0030261	biological_process	chromosome condensation
D	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
D	0042594	biological_process	response to starvation
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	1990084	cellular_component	DnaA-Dps complex
E	0003677	molecular_function	DNA binding
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006950	biological_process	response to stress
E	0008199	molecular_function	ferric iron binding
E	0009295	cellular_component	nucleoid
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0016722	molecular_function	oxidoreductase activity, acting on metal ions
E	0030261	biological_process	chromosome condensation
E	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
E	0042594	biological_process	response to starvation
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
E	1990084	cellular_component	DnaA-Dps complex
F	0003677	molecular_function	DNA binding
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006950	biological_process	response to stress
F	0008199	molecular_function	ferric iron binding
F	0009295	cellular_component	nucleoid
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0016722	molecular_function	oxidoreductase activity, acting on metal ions
F	0030261	biological_process	chromosome condensation
F	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
F	0042594	biological_process	response to starvation
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
F	1990084	cellular_component	DnaA-Dps complex
G	0003677	molecular_function	DNA binding
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0006879	biological_process	intracellular iron ion homeostasis
G	0006950	biological_process	response to stress
G	0008199	molecular_function	ferric iron binding
G	0009295	cellular_component	nucleoid
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0016722	molecular_function	oxidoreductase activity, acting on metal ions
G	0030261	biological_process	chromosome condensation
G	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
G	0042594	biological_process	response to starvation
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
G	1990084	cellular_component	DnaA-Dps complex
H	0003677	molecular_function	DNA binding
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006950	biological_process	response to stress
H	0008199	molecular_function	ferric iron binding
H	0009295	cellular_component	nucleoid
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0016722	molecular_function	oxidoreductase activity, acting on metal ions
H	0030261	biological_process	chromosome condensation
H	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
H	0042594	biological_process	response to starvation
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
H	1990084	cellular_component	DnaA-Dps complex
I	0003677	molecular_function	DNA binding
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006950	biological_process	response to stress
I	0008199	molecular_function	ferric iron binding
I	0009295	cellular_component	nucleoid
I	0016020	cellular_component	membrane
I	0016491	molecular_function	oxidoreductase activity
I	0016722	molecular_function	oxidoreductase activity, acting on metal ions
I	0030261	biological_process	chromosome condensation
I	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
I	0042594	biological_process	response to starvation
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
I	1990084	cellular_component	DnaA-Dps complex
J	0003677	molecular_function	DNA binding
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0006879	biological_process	intracellular iron ion homeostasis
J	0006950	biological_process	response to stress
J	0008199	molecular_function	ferric iron binding
J	0009295	cellular_component	nucleoid
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0016722	molecular_function	oxidoreductase activity, acting on metal ions
J	0030261	biological_process	chromosome condensation
J	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
J	0042594	biological_process	response to starvation
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
J	1990084	cellular_component	DnaA-Dps complex
K	0003677	molecular_function	DNA binding
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006950	biological_process	response to stress
K	0008199	molecular_function	ferric iron binding
K	0009295	cellular_component	nucleoid
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0016722	molecular_function	oxidoreductase activity, acting on metal ions
K	0030261	biological_process	chromosome condensation
K	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
K	0042594	biological_process	response to starvation
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
K	1990084	cellular_component	DnaA-Dps complex
L	0003677	molecular_function	DNA binding
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0006879	biological_process	intracellular iron ion homeostasis
L	0006950	biological_process	response to stress
L	0008199	molecular_function	ferric iron binding
L	0009295	cellular_component	nucleoid
L	0016020	cellular_component	membrane
L	0016491	molecular_function	oxidoreductase activity
L	0016722	molecular_function	oxidoreductase activity, acting on metal ions
L	0030261	biological_process	chromosome condensation
L	0032297	biological_process	negative regulation of DNA-templated DNA replication initiation
L	0042594	biological_process	response to starvation
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
L	1990084	cellular_component	DnaA-Dps complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue CL A 201

Chain	Residue
G	LYS105

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Functional Information from PROSITE/UniProt

site_id	PS00818
Number of Residues	17
Details	DPS_1 Dps protein family signature 1. HWnMrGanfiaVHemlD

Chain	Residue	Details
A	HIS51-ASP67

---

site_id	PS00819
Number of Residues	15
Details	DPS_2 Dps protein family signature 2. LDtMAERavqLGgvA

Chain	Residue	Details
A	LEU77-ALA91

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	HIS51
J	HIS51
K	HIS51
L	HIS51
B	HIS51
C	HIS51
D	HIS51
E	HIS51
F	HIS51
G	HIS51
H	HIS51
I	HIS51

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: in other chain

Chain	Residue	Details
A	ASP78
J	ASP78
K	ASP78
L	ASP78
B	ASP78
C	ASP78
D	ASP78
E	ASP78
F	ASP78
G	ASP78
H	ASP78
I	ASP78

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
A	GLU82
J	GLU82
K	GLU82
L	GLU82
B	GLU82
C	GLU82
D	GLU82
E	GLU82
F	GLU82
G	GLU82
H	GLU82
I	GLU82

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