5XFY
Crystal structure of a novel PET hydrolase S131A mutant from Ideonella sakaiensis 201-F6
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008126 | molecular_function | acetylesterase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042178 | biological_process | xenobiotic catabolic process |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| A | 0071310 | biological_process | cellular response to organic substance |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | GLY57 |
| A | TYR58 |
| A | ARG103 |
| A | ALA131 |
| A | MET132 |
| A | HIS208 |
| A | GOL304 |
| A | HOH452 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | THR22 |
| A | ASP157 |
| A | SER159 |
| A | ASN161 |
| A | PHE162 |
| A | HOH407 |
| A | HOH410 |
| A | GLY19 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | TYR3 |
| A | LYS148 |
| A | ASN235 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | TYR58 |
| A | SER96 |
| A | ALA100 |
| A | SO4301 |
| A | HOH404 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000305|PubMed:29235460, ECO:0000305|PubMed:29374183, ECO:0000305|PubMed:29603535, ECO:0000305|PubMed:29666242 |
| Chain | Residue | Details |
| A | ALA131 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Charge relay system => ECO:0000305|PubMed:29235460, ECO:0000305|PubMed:29374183, ECO:0000305|PubMed:29603535, ECO:0000305|PubMed:29666242 |
| Chain | Residue | Details |
| A | ASP177 | |
| A | HIS208 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29235460 |
| Chain | Residue | Details |
| A | MET132 | |
| A | TYR58 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:29235460, ECO:0000305|PubMed:29666242 |
| Chain | Residue | Details |
| A | TRP156 |
