5XFO

Structure of the N-terminal domains of PHF1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006974	biological_process	cellular response to DNA damage stimulus
A	0031060	biological_process	regulation of histone methylation
A	0035064	molecular_function	methylated histone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 401

Chain	Residue
A	CYS107
A	CYS110
A	CYS136
A	CYS139

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 402

Chain	Residue
A	CYS90
A	CYS93
A	HIS115
A	CYS118

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 403

Chain	Residue
A	CYS191
A	HIS212
A	CYS215
A	CYS189

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 404

Chain	Residue
A	CYS204
A	CYS207
A	CYS234
A	CYS237

---

Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	50
Details	ZF_PHD_1 Zinc finger PHD-type signature. CcvCrsetvvpgnrl..................................VsCek..Crha.YHqdChvprapapgegegts..............................WvCrqC

Chain	Residue	Details
A	CYS90-CYS139
A	CYS189-CYS237

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	57
Details	Domain: {"description":"Tudor"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	55
Details	Zinc finger: {"description":"PHD-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	54
Details	Zinc finger: {"description":"PHD-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---