5XBT
The structure of BrlR bound to c-di-GMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0001216 | molecular_function | DNA-binding transcription activator activity |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032993 | cellular_component | protein-DNA complex |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0001216 | molecular_function | DNA-binding transcription activator activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0032993 | cellular_component | protein-DNA complex |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue C2E A 301 |
| Chain | Residue |
| A | SER0 |
| B | ARG31 |
| B | SER34 |
| B | ASP35 |
| B | TYR270 |
| B | C2E301 |
| A | MET1 |
| A | ARG31 |
| A | GLY33 |
| A | SER34 |
| A | ASP35 |
| A | ASN36 |
| A | TYR40 |
| A | HOH413 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue C2E A 302 |
| Chain | Residue |
| A | GLU63 |
| A | ALA64 |
| A | ARG67 |
| A | ARG70 |
| A | PHE83 |
| A | ARG86 |
| B | ARG67 |
| B | ARG86 |
| B | C2E302 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ARG67 |
| A | ASP71 |
| A | ALA73 |
| A | ARG79 |
| A | HIS82 |
| A | PHE83 |
| A | ARG86 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | TYR137 |
| B | TYR137 |
| B | GOL304 |
| B | HOH408 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 305 |
| Chain | Residue |
| A | ARG127 |
| A | PHE130 |
| A | TYR170 |
| A | GLU188 |
| A | TYR248 |
| A | TYR266 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 306 |
| Chain | Residue |
| A | HIS20 |
| A | TYR21 |
| A | ARG56 |
| A | LEU62 |
| A | HOH411 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 307 |
| Chain | Residue |
| A | HIS114 |
| A | HIS231 |
| A | HOH418 |
| B | ARG118 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue IMD A 308 |
| Chain | Residue |
| A | TRP150 |
| A | PHE253 |
| A | HOH485 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue C2E B 301 |
| Chain | Residue |
| A | ARG31 |
| A | ASP35 |
| A | TYR270 |
| A | C2E301 |
| B | SER0 |
| B | MET1 |
| B | ARG31 |
| B | GLY33 |
| B | SER34 |
| B | ASP35 |
| B | ASN36 |
| B | TYR40 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue C2E B 302 |
| Chain | Residue |
| A | ARG67 |
| A | ARG86 |
| A | C2E302 |
| B | GLU63 |
| B | ALA64 |
| B | ARG67 |
| B | ARG70 |
| B | PHE83 |
| B | ARG86 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| B | ASP71 |
| B | ARG79 |
| B | PHE83 |
| B | ARG86 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 304 |
| Chain | Residue |
| A | TYR137 |
| B | TYR137 |
| B | PRO142 |
| B | HOH408 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 305 |
| Chain | Residue |
| B | ARG127 |
| B | PHE130 |
| B | TYR170 |
| B | TYR248 |
| B | TYR266 |
| B | HOH413 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 306 |
| Chain | Residue |
| B | HIS20 |
| B | TYR21 |
| B | ARG56 |
| B | HOH401 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 307 |
| Chain | Residue |
| A | THR111 |
| A | ARG118 |
| A | HOH406 |
| B | HIS114 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue IMD B 308 |
| Chain | Residue |
| B | SER169 |
| B | PHE253 |
