Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5XAT

Structural insights into the elevator-like mechanism of the sodium/citrate symporter CitS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006101	biological_process	citrate metabolic process
A	0006811	biological_process	monoatomic ion transport
A	0006814	biological_process	sodium ion transport
A	0015293	molecular_function	symporter activity
A	0015711	biological_process	organic anion transport
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0046872	molecular_function	metal ion binding
A	0055085	biological_process	transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0006101	biological_process	citrate metabolic process
B	0006811	biological_process	monoatomic ion transport
B	0006814	biological_process	sodium ion transport
B	0015293	molecular_function	symporter activity
B	0015711	biological_process	organic anion transport
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0046872	molecular_function	metal ion binding
B	0055085	biological_process	transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0006101	biological_process	citrate metabolic process
C	0006811	biological_process	monoatomic ion transport
C	0006814	biological_process	sodium ion transport
C	0015293	molecular_function	symporter activity
C	0015711	biological_process	organic anion transport
C	0016020	cellular_component	membrane
C	0022857	molecular_function	transmembrane transporter activity
C	0046872	molecular_function	metal ion binding
C	0055085	biological_process	transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0006101	biological_process	citrate metabolic process
D	0006811	biological_process	monoatomic ion transport
D	0006814	biological_process	sodium ion transport
D	0015293	molecular_function	symporter activity
D	0015711	biological_process	organic anion transport
D	0016020	cellular_component	membrane
D	0022857	molecular_function	transmembrane transporter activity
D	0046872	molecular_function	metal ion binding
D	0055085	biological_process	transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	64
Details	Transmembrane: {"description":"Helical; Name=TM 1","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	168
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	80
Details	Transmembrane: {"description":"Helical; Name=TM 2","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	96
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	56
Details	Transmembrane: {"description":"Helical; Name=TM 3","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	56
Details	Transmembrane: {"description":"Helical; Name=TM 4","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	116
Details	Transmembrane: {"description":"Helical; Name=TM 5","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	144
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"10825453","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	28
Details	Intramembrane: {"description":"Helical; Name=TM 6 (HP1)","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	80
Details	Transmembrane: {"description":"Helical; Name=TM 7","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	88
Details	Transmembrane: {"description":"Helical; Name=TM 8","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=TM 9","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	92
Details	Transmembrane: {"description":"Helical; Name=TM 10","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	84
Details	Transmembrane: {"description":"Helical; Name=TM 11","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	100
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"10825453","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	28
Details	Intramembrane: {"description":"Helical; Name=TM 12 (HP2)","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	84
Details	Transmembrane: {"description":"Helical; Name=TM 13","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5X9R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	7
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8810332","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)