5X9R
Structural insights into the elevator-like mechanism of the sodium/citrate symporter CitS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006101 | biological_process | citrate metabolic process |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006814 | biological_process | sodium ion transport |
| A | 0015293 | molecular_function | symporter activity |
| A | 0015711 | biological_process | organic anion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006101 | biological_process | citrate metabolic process |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006814 | biological_process | sodium ion transport |
| B | 0015293 | molecular_function | symporter activity |
| B | 0015711 | biological_process | organic anion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Transmembrane: {"description":"Helical; Name=TM 1","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 84 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=TM 2","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 48 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 28 |
| Details | Transmembrane: {"description":"Helical; Name=TM 3","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 28 |
| Details | Transmembrane: {"description":"Helical; Name=TM 4","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 58 |
| Details | Transmembrane: {"description":"Helical; Name=TM 5","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 72 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"10825453","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 14 |
| Details | Intramembrane: {"description":"Helical; Name=TM 6 (HP1)","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=TM 7","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 44 |
| Details | Transmembrane: {"description":"Helical; Name=TM 8","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 30 |
| Details | Transmembrane: {"description":"Helical; Name=TM 9","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=TM 10","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 42 |
| Details | Transmembrane: {"description":"Helical; Name=TM 11","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 50 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"10825453","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 14 |
| Details | Intramembrane: {"description":"Helical; Name=TM 12 (HP2)","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 42 |
| Details | Transmembrane: {"description":"Helical; Name=TM 13","evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5XAR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28566738","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5X9R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XAT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
