5X9H
Crystal structure of the Mg2+ channel MgtE in complex with ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006812 | biological_process | monoatomic cation transport |
| A | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
| A | 0015095 | molecular_function | magnesium ion transmembrane transporter activity |
| A | 0015693 | biological_process | magnesium ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098655 | biological_process | monoatomic cation transmembrane transport |
| A | 1903830 | biological_process | magnesium ion transmembrane transport |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006812 | biological_process | monoatomic cation transport |
| B | 0008324 | molecular_function | monoatomic cation transmembrane transporter activity |
| B | 0015095 | molecular_function | magnesium ion transmembrane transporter activity |
| B | 0015693 | biological_process | magnesium ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098655 | biological_process | monoatomic cation transmembrane transport |
| B | 1903830 | biological_process | magnesium ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue ATP A 501 |
| Chain | Residue |
| A | TYR170 |
| A | PRO231 |
| B | GLU166 |
| B | TYR169 |
| A | VAL183 |
| A | SER185 |
| A | ARG187 |
| A | ASN203 |
| A | LYS205 |
| A | VAL206 |
| A | VAL207 |
| A | PHE227 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | ASP432 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 504 |
| Chain | Residue |
| A | ASP259 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 505 |
| Chain | Residue |
| A | ASP91 |
| A | ASP247 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 506 |
| Chain | Residue |
| A | ALA223 |
| A | ASP226 |
| B | ASP250 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 507 |
| Chain | Residue |
| A | ASP95 |
| A | GLY136 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 508 |
| Chain | Residue |
| A | GLU59 |
| B | ASP226 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 509 |
| Chain | Residue |
| A | ASP226 |
| B | GLU59 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue ATP B 501 |
| Chain | Residue |
| A | GLU166 |
| A | TYR169 |
| B | TYR170 |
| B | VAL183 |
| B | SER185 |
| B | ARG187 |
| B | ASP188 |
| B | ASN203 |
| B | LYS205 |
| B | VAL206 |
| B | VAL207 |
| B | PHE227 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 502 |
| Chain | Residue |
| B | ALA223 |
| B | ASP224 |
| B | ASP226 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 504 |
| Chain | Residue |
| B | GLU216 |
| B | ASP259 |
| B | ASP418 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 505 |
| Chain | Residue |
| B | ASP91 |
| B | GLU166 |
| B | ASP247 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue MG B 506 |
| Chain | Residue |
| B | ASP95 |
| B | GLY136 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 234 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"25367295","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U9N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WIB","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"17700703","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25367295","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"17700703","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25367295","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 124 |
| Details | Domain: {"description":"CBS 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 112 |
| Details | Domain: {"description":"CBS 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5X9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5X9H","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5X9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5X9H","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5X9H","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZY9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25367295","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U9N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
