Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004412 | molecular_function | homoserine dehydrogenase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0009088 | biological_process | threonine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 45 |
| Details | binding site for residue 80F A 501 |
| Chain | Residue |
| A | PHE6 |
| A | SER73 |
| A | SER74 |
| A | PRO82 |
| A | THR100 |
| A | ASN101 |
| A | LYS102 |
| A | GLY127 |
| A | SER131 |
| A | ASN155 |
| A | GLY156 |
| A | GLY7 |
| A | THR157 |
| A | GLY182 |
| A | TYR183 |
| A | ALA184 |
| A | GLU185 |
| A | GLU186 |
| A | ASP191 |
| A | ASP196 |
| A | LYS200 |
| A | ALA283 |
| A | TYR8 |
| A | GLY284 |
| A | PRO285 |
| A | ALA288 |
| A | TLA502 |
| A | HOH601 |
| A | HOH602 |
| A | HOH604 |
| A | HOH615 |
| A | HOH637 |
| A | HOH642 |
| A | GLY9 |
| A | HOH643 |
| A | HOH644 |
| A | HOH662 |
| A | HOH669 |
| A | HOH690 |
| A | HOH697 |
| A | ASN10 |
| A | VAL11 |
| A | THR37 |
| A | ARG38 |
| A | VAL72 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue TLA A 502 |
| Chain | Residue |
| A | HIS20 |
| A | ARG23 |
| A | THR37 |
| A | ARG38 |
| A | ARG39 |
| A | 80F501 |
| A | HOH604 |
| A | HOH609 |
| A | HOH628 |
| A | HOH651 |
Functional Information from PROSITE/UniProt
| site_id | PS01042 |
| Number of Residues | 23 |
| Details | HOMOSER_DHGENASE Homoserine dehydrogenase signature. AqrrGYAee.DPtlDInGfDaaaK |
| Chain | Residue | Details |
| A | ALA178-LYS200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PIRSR","id":"PIRSR036497-1","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O58802","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35835834","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7F4C","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P31116","evidenceCode":"ECO:0000250"}]} |
