Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004798 | molecular_function | dTMP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006227 | biological_process | dUDP biosynthetic process |
| A | 0006233 | biological_process | dTDP biosynthetic process |
| A | 0006235 | biological_process | dTTP biosynthetic process |
| A | 0009165 | biological_process | nucleotide biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004798 | molecular_function | dTMP kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006227 | biological_process | dUDP biosynthetic process |
| B | 0006233 | biological_process | dTDP biosynthetic process |
| B | 0006235 | biological_process | dTTP biosynthetic process |
| B | 0009165 | biological_process | nucleotide biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue MG A 201 |
| Chain | Residue |
| A | VAL175 |
| B | HOH335 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 202 |
| Chain | Residue |
| A | GLU169 |
| A | GLY171 |
| A | ARG172 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 203 |
| Chain | Residue |
| A | GLY13 |
| A | GLY15 |
| A | LYS16 |
| A | THR17 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 204 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 205 |
| Chain | Residue |
| A | ARG22 |
| A | ARG139 |
| A | HOH301 |
| A | HOH323 |
| site_id | AC6 |
| Number of Residues | 23 |
| Details | binding site for residue ATP B 201 |
| Chain | Residue |
| B | PRO2 |
| B | LEU11 |
| B | ASP12 |
| B | GLY13 |
| B | SER14 |
| B | GLY15 |
| B | LYS16 |
| B | THR17 |
| B | THR18 |
| B | GLU28 |
| B | GLY31 |
| B | ARG91 |
| B | ARG140 |
| B | VAL141 |
| B | LEU180 |
| B | PRO181 |
| B | GLU182 |
| B | ILE185 |
| B | MG202 |
| B | PEG206 |
| B | HOH301 |
| B | HOH304 |
| B | HOH322 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 202 |
| Chain | Residue |
| B | THR17 |
| B | ATP201 |
| B | HOH301 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 203 |
| Chain | Residue |
| B | PHE65 |
| B | SER96 |
| B | GLN100 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 204 |
| Chain | Residue |
| A | HOH335 |
| B | GLU169 |
| B | GLY171 |
| B | ARG172 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 205 |
| Chain | Residue |
| B | GLU113 |
| B | ARG116 |
| B | GLU117 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 206 |
| Chain | Residue |
| B | GLU28 |
| B | ARG32 |
| B | VAL34 |
| B | GLU182 |
| B | ATP201 |
Functional Information from PROSITE/UniProt
| site_id | PS01331 |
| Number of Residues | 13 |
| Details | THYMIDYLATE_KINASE Thymidylate kinase signature. ISDRYldSSlAYQ |
| Chain | Residue | Details |
| A | ILE88-GLN100 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00165","evidenceCode":"ECO:0000255"}]} |
