Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 1301 |
| Chain | Residue |
| A | GLU855 |
| A | GLU857 |
| A | SER880 |
| A | GLY883 |
| A | ASP979 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 1302 |
| Chain | Residue |
| A | HOH2488 |
| A | GLU995 |
| A | LYS1013 |
| A | ALA1016 |
| A | ASP1111 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 1303 |
| Chain | Residue |
| A | ASP1134 |
| A | GLU1136 |
| A | ARG1173 |
| A | GLN1176 |
| A | ASP1273 |
| A | HOH2005 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NI A 1501 |
| Chain | Residue |
| A | HIS187 |
| A | HIS190 |
| A | ASP196 |
| A | HOH2133 |
| A | HOH2195 |
| A | HOH2225 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1601 |
| Chain | Residue |
| A | HOH2048 |
| A | HOH2167 |
| A | HOH2222 |
| A | HOH2277 |
| A | HOH2536 |
| A | HOH2543 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 1602 |
| Chain | Residue |
| A | HOH2004 |
| A | HOH2095 |
| A | HOH2158 |
| A | HOH2542 |
| A | HOH2544 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1603 |
| Chain | Residue |
| A | HOH2261 |
| A | HOH2276 |
| A | HOH2421 |
| A | HOH2452 |
| A | HOH2482 |
| A | HOH2552 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1604 |
| Chain | Residue |
| A | ASP316 |
| A | HOH2230 |
| A | HOH2232 |
| A | HOH2243 |
| A | HOH2383 |
| A | HOH2504 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue TB A 1605 |
| Chain | Residue |
| A | GLU283 |
| A | GLY285 |
| A | GLU290 |
| A | HOH2012 |
| B | GLN571 |
| B | HOH2053 |
| B | HOH2083 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue TB A 1606 |
| Chain | Residue |
| A | GLU605 |
| A | GLU608 |
| A | HOH2035 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue TB A 1607 |
| Chain | Residue |
| A | GLU726 |
| A | GLU763 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue TB A 1608 |
| Chain | Residue |
| A | ASP376 |
| A | ASP1183 |
| A | HOH2204 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 1701 |
| Chain | Residue |
| A | GLY43 |
| A | ALA44 |
| A | ARG126 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 1702 |
| Chain | Residue |
| A | ARG169 |
| A | HIS187 |
| A | HOH2338 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 1703 |
| Chain | Residue |
| A | TYR403 |
| A | GLN404 |
| A | GLN405 |
| A | HOH2017 |
| A | HOH2055 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1704 |
| Chain | Residue |
| A | SER758 |
| A | ARG785 |
| A | GLY843 |
| A | HOH2166 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 1705 |
| Chain | Residue |
| A | ARG861 |
| A | ARG869 |
| A | HOH2223 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue MES A 1706 |
| Chain | Residue |
| A | PHE1011 |
| A | ARG1045 |
| A | LEU1079 |
| A | TRP1080 |
| A | ASP1195 |
| A | HOH2241 |
| A | HOH2350 |
| A | HOH2373 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue MES A 1707 |
| Chain | Residue |
| A | GLN370 |
| A | TYR373 |
| A | ASP374 |
| A | ASN1213 |
| A | TYR1267 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 1801 |
| Chain | Residue |
| A | SER214 |
| A | ASP215 |
| A | TYR231 |
| A | ARG239 |
| A | TYR241 |
| A | THR242 |
| A | LYS243 |
| A | HOH2328 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1802 |
| Chain | Residue |
| A | TYR602 |
| A | GLU605 |
| A | PHE729 |
| A | THR730 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1803 |
| Chain | Residue |
| A | THR670 |
| A | TYR1033 |
| A | ARG1093 |
| A | HOH2507 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1804 |
| Chain | Residue |
| A | GLU500 |
| A | PRO544 |
| A | SER545 |
| A | LEU548 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 1708 |
| Chain | Residue |
| A | ASP376 |
| B | ARG398 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue TB B 1606 |
| Chain | Residue |
| A | GLN571 |
| A | HOH2138 |
| A | HOH2146 |
| B | GLU283 |
| B | GLY285 |
| B | GLU290 |
| B | HOH2108 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 1301 |
| Chain | Residue |
| B | GLU855 |
| B | GLU857 |
| B | SER880 |
| B | GLY883 |
| B | ASP979 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 1302 |
| Chain | Residue |
| B | GLU995 |
| B | LYS1013 |
| B | ALA1016 |
| B | ASP1111 |
| B | HOH2438 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 1303 |
| Chain | Residue |
| B | ASP1134 |
| B | GLU1136 |
| B | ARG1173 |
| B | GLN1176 |
| B | ASP1273 |
| B | GLU1274 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue NI B 1501 |
| Chain | Residue |
| B | HIS187 |
| B | HIS190 |
| B | ASP196 |
| B | HOH2052 |
| B | HOH2113 |
| B | HOH2378 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1601 |
| Chain | Residue |
| B | HOH2042 |
| B | HOH2045 |
| B | HOH2056 |
| B | HOH2267 |
| B | HOH2562 |
| B | HOH2575 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1602 |
| Chain | Residue |
| B | HOH2012 |
| B | HOH2187 |
| B | HOH2242 |
| B | HOH2544 |
| B | HOH2551 |
| B | HOH2567 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1603 |
| Chain | Residue |
| B | ASP316 |
| B | HOH2111 |
| B | HOH2134 |
| B | HOH2164 |
| B | HOH2257 |
| B | HOH2479 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue TB B 1604 |
| Chain | Residue |
| B | GLU605 |
| B | GLU608 |
| B | HOH2206 |
| B | HOH2251 |
| site_id | AF7 |
| Number of Residues | 2 |
| Details | binding site for residue TB B 1605 |
| Chain | Residue |
| B | GLU726 |
| B | GLU763 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1701 |
| Chain | Residue |
| B | GLY43 |
| B | ALA44 |
| B | ARG126 |
| site_id | AF9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1702 |
| Chain | Residue |
| B | ARG169 |
| B | HIS187 |
| B | HOH2015 |
| site_id | AG1 |
| Number of Residues | 4 |
| Details | binding site for residue MES B 1703 |
| Chain | Residue |
| B | GLN370 |
| B | TYR373 |
| B | ASN1213 |
| B | TYR1267 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 1704 |
| Chain | Residue |
| B | GLN404 |
| B | GLN405 |
| B | HOH2197 |
| B | HOH2202 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 1705 |
| Chain | Residue |
| B | TYR671 |
| B | SER672 |
| B | GLN675 |
| B | ARG1093 |
| site_id | AG4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1706 |
| Chain | Residue |
| B | SER758 |
| B | ARG785 |
| B | GLY843 |
| site_id | AG5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1707 |
| Chain | Residue |
| B | ARG861 |
| B | ARG869 |
| B | HOH2054 |
| site_id | AG6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 1708 |
| Chain | Residue |
| B | ALA942 |
| B | TRP943 |
| B | SER944 |
| B | HOH2078 |
| site_id | AG7 |
| Number of Residues | 6 |
| Details | binding site for residue MES B 1709 |
| Chain | Residue |
| B | PHE1011 |
| B | ARG1045 |
| B | LEU1079 |
| B | TRP1080 |
| B | ASP1195 |
| B | HOH2301 |
| site_id | AG8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1710 |
| Chain | Residue |
| B | ALA1201 |
| B | THR1202 |
| B | ARG1279 |
| site_id | AG9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1711 |
| Chain | Residue |
| B | ARG1210 |
| B | VAL1240 |
| B | TRP1241 |
| site_id | AH1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 1801 |
| Chain | Residue |
| B | SER214 |
| B | ASP215 |
| B | TYR231 |
| B | ARG239 |
| B | TYR241 |
| B | THR242 |
| B | LYS243 |
| B | HOH2081 |
| site_id | AH2 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 1802 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 1803 |
| Chain | Residue |
| B | PHE496 |
| B | GLU500 |
| B | SER545 |
| B | LEU548 |
| B | HOH2169 |
