Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 1301 |
| Chain | Residue |
| A | GLU855 |
| A | GLU857 |
| A | SER880 |
| A | GLY883 |
| A | ASP979 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 1302 |
| Chain | Residue |
| A | HOH2467 |
| A | GLU995 |
| A | LYS1013 |
| A | ALA1016 |
| A | ASP1111 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 1303 |
| Chain | Residue |
| A | ASP1134 |
| A | GLU1136 |
| A | ARG1173 |
| A | GLN1176 |
| A | ASP1273 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NI A 1501 |
| Chain | Residue |
| A | HIS187 |
| A | HIS190 |
| A | ASP196 |
| A | HOH2018 |
| A | HOH2193 |
| A | HOH2342 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1601 |
| Chain | Residue |
| A | GLU283 |
| A | GLY285 |
| A | GLU290 |
| B | GLN571 |
| B | HOH2358 |
| B | HOH2537 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1602 |
| Chain | Residue |
| A | HOH2065 |
| A | HOH2277 |
| A | HOH2359 |
| A | HOH2383 |
| A | HOH2914 |
| A | HOH2948 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1603 |
| Chain | Residue |
| A | HOH2034 |
| A | HOH2063 |
| A | HOH2556 |
| A | HOH2889 |
| A | HOH2892 |
| A | HOH2913 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1604 |
| Chain | Residue |
| A | HOH2290 |
| A | HOH2560 |
| A | HOH2833 |
| A | HOH2936 |
| A | HOH2971 |
| A | HOH2979 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1605 |
| Chain | Residue |
| A | HOH2204 |
| A | HOH2270 |
| A | HOH2852 |
| A | HOH2887 |
| A | HOH2890 |
| A | HOH2974 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1606 |
| Chain | Residue |
| A | ASP316 |
| A | HOH2310 |
| A | HOH2416 |
| A | HOH2459 |
| A | HOH2596 |
| A | HOH2842 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1607 |
| Chain | Residue |
| A | HOH2119 |
| A | HOH2296 |
| A | HOH2692 |
| A | HOH2740 |
| A | HOH2835 |
| A | HOH2968 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1701 |
| Chain | Residue |
| A | GLY43 |
| A | ALA44 |
| A | ARG126 |
| A | HOH2250 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 1702 |
| Chain | Residue |
| A | ARG169 |
| A | HIS187 |
| A | HOH2675 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 1703 |
| Chain | Residue |
| A | TYR403 |
| A | GLN404 |
| A | GLN405 |
| A | HOH2001 |
| A | HOH2081 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 1704 |
| Chain | Residue |
| A | SER758 |
| A | ARG785 |
| A | GLY843 |
| A | SER844 |
| A | HOH2083 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1705 |
| Chain | Residue |
| A | ARG861 |
| A | ARG869 |
| A | HOH2490 |
| A | HOH2510 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1706 |
| Chain | Residue |
| A | ALA942 |
| A | TRP943 |
| A | SER944 |
| A | HOH2321 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue MES A 1707 |
| Chain | Residue |
| A | PHE1011 |
| A | ARG1045 |
| A | LEU1079 |
| A | TRP1080 |
| A | ASP1195 |
| A | HOH2236 |
| A | HOH2440 |
| A | HOH2766 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue MES A 1708 |
| Chain | Residue |
| A | TYR1267 |
| A | GLN370 |
| A | TYR373 |
| A | ASN1213 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 1801 |
| Chain | Residue |
| A | SER214 |
| A | ASP215 |
| A | TYR231 |
| A | ARG239 |
| A | TYR241 |
| A | THR242 |
| A | LYS243 |
| A | HOH2425 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1802 |
| Chain | Residue |
| A | TYR602 |
| A | GLU605 |
| A | PHE729 |
| A | THR730 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1803 |
| Chain | Residue |
| A | GLN669 |
| A | THR670 |
| A | TYR1033 |
| A | ARG1093 |
| A | HOH2435 |
| A | HOH2854 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1804 |
| Chain | Residue |
| A | GLU500 |
| A | PRO544 |
| A | SER545 |
| A | LEU548 |
| A | HOH2005 |
| A | HOH2484 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1805 |
| Chain | Residue |
| A | ARG76 |
| A | ILE93 |
| A | TRP99 |
| A | TYR249 |
| A | HOH2008 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1806 |
| Chain | Residue |
| A | ASP1160 |
| A | LEU1165 |
| A | ARG1177 |
| A | TYR1179 |
| A | HIS1271 |
| A | HOH2606 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1807 |
| Chain | Residue |
| A | ARG1112 |
| A | THR1121 |
| A | THR1122 |
| A | LEU1123 |
| A | GLU1126 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1608 |
| Chain | Residue |
| A | HOH2233 |
| A | HOH2672 |
| A | HOH2901 |
| A | HOH2976 |
| A | HOH2977 |
| A | HOH2978 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1607 |
| Chain | Residue |
| A | GLN571 |
| A | HOH2511 |
| B | GLU283 |
| B | GLY285 |
| B | GLU290 |
| B | HOH2456 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1601 |
| Chain | Residue |
| B | HOH2083 |
| B | HOH2239 |
| B | HOH2913 |
| B | HOH2972 |
| B | HOH2974 |
| B | HOH2975 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 1301 |
| Chain | Residue |
| B | GLU855 |
| B | GLU857 |
| B | SER880 |
| B | GLY883 |
| B | ASP979 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 1302 |
| Chain | Residue |
| B | GLU995 |
| B | LYS1013 |
| B | ALA1016 |
| B | ASP1111 |
| B | HOH2547 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 1303 |
| Chain | Residue |
| B | ASP1134 |
| B | GLU1136 |
| B | ARG1173 |
| B | GLN1176 |
| B | ASP1273 |
| B | GLU1274 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue NI B 1501 |
| Chain | Residue |
| B | HIS187 |
| B | HIS190 |
| B | ASP196 |
| B | HOH2016 |
| B | HOH2178 |
| B | HOH2478 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1602 |
| Chain | Residue |
| B | HOH2169 |
| B | HOH2192 |
| B | HOH2275 |
| B | HOH2287 |
| B | HOH2914 |
| B | HOH2933 |
| site_id | AF8 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 1603 |
| Chain | Residue |
| B | GLU152 |
| B | HOH2015 |
| B | HOH2145 |
| B | HOH2186 |
| B | HOH2892 |
| B | HOH2896 |
| B | HOH2954 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1604 |
| Chain | Residue |
| B | HOH2100 |
| B | HOH2237 |
| B | HOH2857 |
| B | HOH2862 |
| B | HOH2867 |
| B | HOH2952 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1605 |
| Chain | Residue |
| B | ASP316 |
| B | HOH2132 |
| B | HOH2357 |
| B | HOH2499 |
| B | HOH2651 |
| B | HOH2852 |
| site_id | AG2 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 1606 |
| Chain | Residue |
| B | ASP969 |
| B | HOH2095 |
| B | HOH2121 |
| B | HOH2330 |
| B | HOH2454 |
| B | HOH2660 |
| B | HOH2969 |
| site_id | AG3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1701 |
| Chain | Residue |
| B | GLY43 |
| B | ALA44 |
| B | ARG126 |
| site_id | AG4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 1702 |
| Chain | Residue |
| B | ARG169 |
| B | HIS187 |
| B | HOH2002 |
| B | HOH2041 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue MES B 1710 |
| Chain | Residue |
| B | GLN370 |
| B | TYR373 |
| B | ASN1213 |
| B | TYR1267 |
| site_id | AG6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1703 |
| Chain | Residue |
| A | ASP376 |
| B | ARG398 |
| B | HOH2397 |
| site_id | AG7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 1704 |
| Chain | Residue |
| B | GLN404 |
| B | GLN405 |
| B | HOH2021 |
| B | HOH2210 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 1705 |
| Chain | Residue |
| B | THR670 |
| B | TYR671 |
| B | SER672 |
| B | GLN675 |
| B | ARG1093 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 1706 |
| Chain | Residue |
| B | ARG861 |
| B | ARG869 |
| B | HOH2488 |
| B | HOH2640 |
| site_id | AH1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 1707 |
| Chain | Residue |
| B | ALA942 |
| B | TRP943 |
| B | SER944 |
| B | HOH2158 |
| B | HOH2300 |
| site_id | AH2 |
| Number of Residues | 8 |
| Details | binding site for residue MES B 1711 |
| Chain | Residue |
| B | PHE1011 |
| B | ARG1045 |
| B | LEU1079 |
| B | TRP1080 |
| B | ASP1195 |
| B | HOH2279 |
| B | HOH2503 |
| B | HOH2753 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 1708 |
| Chain | Residue |
| A | SER919 |
| A | LYS921 |
| B | ASN1199 |
| B | ASN1200 |
| B | HOH2179 |
| site_id | AH4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1709 |
| Chain | Residue |
| B | ALA1201 |
| B | THR1202 |
| B | ARG1279 |
| site_id | AH5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 1801 |
| Chain | Residue |
| B | SER214 |
| B | ASP215 |
| B | TYR231 |
| B | ARG239 |
| B | TYR241 |
| B | THR242 |
| B | LYS243 |
| B | HOH2399 |
| site_id | AH6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 1802 |
| Chain | Residue |
| B | TYR602 |
| B | PHE729 |
| B | THR730 |
| B | HOH2027 |
| B | HOH2246 |
| site_id | AH7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 1803 |
| Chain | Residue |
| B | GLN669 |
| B | THR670 |
| B | GLY1092 |
| B | ARG1093 |
| B | HOH2068 |
| B | HOH2749 |
| site_id | AH8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 1804 |
| Chain | Residue |
| B | PHE496 |
| B | GLU500 |
| B | PRO544 |
| B | SER545 |
| B | LEU548 |
| B | HOH2191 |
| site_id | AH9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 1805 |
| Chain | Residue |
| B | ASP1160 |
| B | LEU1165 |
| B | ARG1177 |
| B | HIS1271 |
| site_id | AI1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 1806 |
| Chain | Residue |
| B | GLU1082 |
| B | ARG1112 |
| B | ILE1120 |
| B | THR1121 |
| B | THR1122 |
| B | LEU1123 |
| B | GLU1126 |
5X7O
