5X7F
Structure of a O-methyltransferase from Mycobacterium tuberculosis at 2.0 resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue SAM A 301 |
| Chain | Residue |
| A | GLY40 |
| A | ILE91 |
| A | GLU92 |
| A | HIS95 |
| A | GLY118 |
| A | ARG119 |
| A | ALA120 |
| A | GLN121 |
| A | ASP138 |
| A | ALA139 |
| A | TYR147 |
| A | ALA41 |
| A | HOH409 |
| A | HOH413 |
| A | VAL42 |
| A | GLY66 |
| A | THR67 |
| A | GLY68 |
| A | VAL71 |
| A | SER72 |
| A | ASP90 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:28580918 |
| Chain | Residue | Details |
| A | HIS164 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01019, ECO:0000269|PubMed:28580918, ECO:0007744|PDB:5X7F |
| Chain | Residue | Details |
| A | VAL42 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0007744|PDB:5X7F |
| Chain | Residue | Details |
| A | GLY66 | |
| A | VAL71 | |
| A | TYR147 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28580918, ECO:0007744|PDB:5X7F |
| Chain | Residue | Details |
| A | SER72 | |
| A | ASP90 | |
| A | HIS95 | |
| A | ALA120 | |
| A | ASP138 |
