5X6O

Intact ATR/Mec1-ATRIP/Ddc2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000077	biological_process	DNA damage checkpoint signaling
C	0000722	biological_process	telomere maintenance via recombination
C	0000723	biological_process	telomere maintenance
C	0004672	molecular_function	protein kinase activity
C	0004674	molecular_function	protein serine/threonine kinase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005657	cellular_component	replication fork
C	0005694	cellular_component	chromosome
C	0005739	cellular_component	mitochondrion
C	0006260	biological_process	DNA replication
C	0006275	biological_process	regulation of DNA replication
C	0006310	biological_process	DNA recombination
C	0007131	biological_process	reciprocal meiotic recombination
C	0016301	molecular_function	kinase activity
C	0042770	biological_process	signal transduction in response to DNA damage
C	0051276	biological_process	chromosome organization
C	0070310	cellular_component	ATR-ATRIP complex
C	0106310	molecular_function	protein serine kinase activity
C	1904594	biological_process	regulation of termination of RNA polymerase II transcription
C	2000105	biological_process	positive regulation of DNA-templated DNA replication
C	2000779	biological_process	regulation of double-strand break repair
G	0000077	biological_process	DNA damage checkpoint signaling
G	0000228	cellular_component	nuclear chromosome
G	0003684	molecular_function	damaged DNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0007004	biological_process	telomere maintenance via telomerase
G	0045184	biological_process	establishment of protein localization
G	0070310	cellular_component	ATR-ATRIP complex
G	2000779	biological_process	regulation of double-strand break repair

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Region: {"description":"G-loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Region: {"description":"Catalytic loop","evidences":[{"source":"PROSITE-ProRule","id":"PRU00269","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---