5X6O

Intact ATR/Mec1-ATRIP/Ddc2 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000077	biological_process	DNA damage checkpoint signaling
C	0000722	biological_process	telomere maintenance via recombination
C	0000723	biological_process	telomere maintenance
C	0004672	molecular_function	protein kinase activity
C	0004674	molecular_function	protein serine/threonine kinase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0005739	cellular_component	mitochondrion
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0006260	biological_process	DNA replication
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0006325	biological_process	chromatin organization
C	0007131	biological_process	reciprocal meiotic recombination
C	0016301	molecular_function	kinase activity
C	0019219	biological_process	regulation of nucleobase-containing compound metabolic process
C	0035556	biological_process	intracellular signal transduction
C	0042770	biological_process	signal transduction in response to DNA damage
C	0051321	biological_process	meiotic cell cycle
C	0070310	cellular_component	ATR-ATRIP complex
C	0106310	molecular_function	protein serine kinase activity
C	2000105	biological_process	positive regulation of DNA-templated DNA replication
C	2000779	biological_process	regulation of double-strand break repair
G	0000077	biological_process	DNA damage checkpoint signaling
G	0000228	cellular_component	nuclear chromosome
G	0003684	molecular_function	damaged DNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0006139	biological_process	nucleobase-containing compound metabolic process
G	0006281	biological_process	DNA repair
G	0006325	biological_process	chromatin organization
G	0007004	biological_process	telomere maintenance via telomerase
G	0045184	biological_process	establishment of protein localization
G	0070310	cellular_component	ATR-ATRIP complex
G	2000779	biological_process	regulation of double-strand break repair

Functional Information from PROSITE/UniProt

site_id	PS00915
Number of Residues	14
Details	PI3_4_KINASE_1 Phosphatidylinositol 3- and 4-kinases signature 1. CKk..EDVRQDnqymQ

Chain	Residue	Details
C	CYS2079-GLN2092

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site_id	PS00916
Number of Residues	21
Details	PI3_4_KINASE_2 Phosphatidylinositol 3- and 4-kinases signature 2. SyAvmaMvgHILgLgDRHceN

Chain	Residue	Details
C	SER2209-ASN2229

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
G	SER10
G	SER11
G	SER76

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