5X62
Crystal structure of a carnosine N-methyltransferase bound by AdoHcy
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005575 | cellular_component | cellular_component |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0030735 | molecular_function | carnosine N-methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0035498 | biological_process | carnosine metabolic process |
| B | 0005575 | cellular_component | cellular_component |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0030735 | molecular_function | carnosine N-methyltransferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0035498 | biological_process | carnosine metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue SAH A 501 |
| Chain | Residue |
| A | GLN108 |
| A | SER234 |
| A | PHE235 |
| A | ASN274 |
| A | PHE275 |
| A | THR279 |
| A | TYR286 |
| A | TYR371 |
| A | HOH601 |
| A | HOH664 |
| A | ARG111 |
| A | GLY146 |
| A | ASN166 |
| A | GLU167 |
| A | PHE168 |
| A | SER169 |
| A | MET172 |
| A | GLY233 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue SAH B 501 |
| Chain | Residue |
| B | GLN108 |
| B | ARG111 |
| B | GLY146 |
| B | GLY148 |
| B | ASN166 |
| B | GLU167 |
| B | PHE168 |
| B | SER169 |
| B | MET172 |
| B | GLY233 |
| B | SER234 |
| B | PHE235 |
| B | ASN274 |
| B | PHE275 |
| B | PHE276 |
| B | THR279 |
| B | TYR286 |
| B | TYR371 |
| B | HOH605 |
| B | HOH651 |
| B | HOH670 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 502 |
| Chain | Residue |
| B | ASN266 |
| B | GLY291 |
| B | HIS292 |
| B | LEU294 |
| B | HOH700 |
| B | HOH704 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q8N4J0 |
| Chain | Residue | Details |
| A | GLN108 | |
| A | ARG111 | |
| A | GLY146 | |
| A | GLU167 | |
| A | PHE235 | |
| A | ASP278 | |
| A | TYR286 | |
| A | HIS309 | |
| A | TYR385 | |
| B | GLN108 | |
| B | ARG111 | |
| B | GLY146 | |
| B | GLU167 | |
| B | PHE235 | |
| B | ASP278 | |
| B | TYR286 | |
| B | HIS309 | |
| B | TYR385 |
