5X45

Crystal structure of 2A protease from Human rhinovirus C15

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0016032	biological_process	viral process
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0016032	biological_process	viral process
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0016032	biological_process	viral process
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0016032	biological_process	viral process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 201

Chain	Residue
A	CYS51
A	CYS53
A	CYS111
A	HIS113

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 201

Chain	Residue
B	CYS51
B	CYS53
B	CYS111
B	HIS113

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN C 201

Chain	Residue
C	CYS53
C	CYS111
C	HIS113
C	CYS51

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN D 201

Chain	Residue
D	CYS51
D	CYS53
D	CYS111
D	HIS113

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: For protease 2A activity => ECO:0000305|PubMed:29633974

Chain	Residue	Details
A	HIS18
D	HIS18
D	ASP34
D	CYS105
A	ASP34
A	CYS105
B	HIS18
B	ASP34
B	CYS105
C	HIS18
C	ASP34
C	CYS105

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:29633974

Chain	Residue	Details
A	CYS51
C	CYS53
C	CYS111
C	HIS113
D	CYS51
D	CYS53
D	CYS111
D	HIS113
A	CYS53
A	CYS111
A	HIS113
B	CYS51
B	CYS53
B	CYS111
B	HIS113
C	CYS51

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