5X2B
Crystal structure of mouse sulfotransferase SULT7A1 complexed with PAP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008146 | molecular_function | sulfotransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051923 | biological_process | sulfation |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008146 | molecular_function | sulfotransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051923 | biological_process | sulfation |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008146 | molecular_function | sulfotransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051923 | biological_process | sulfation |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008146 | molecular_function | sulfotransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051923 | biological_process | sulfation |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008146 | molecular_function | sulfotransferase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0051923 | biological_process | sulfation |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008146 | molecular_function | sulfotransferase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0051923 | biological_process | sulfation |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0008146 | molecular_function | sulfotransferase activity |
| G | 0016740 | molecular_function | transferase activity |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0051923 | biological_process | sulfation |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0008146 | molecular_function | sulfotransferase activity |
| H | 0016740 | molecular_function | transferase activity |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0051923 | biological_process | sulfation |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0008146 | molecular_function | sulfotransferase activity |
| I | 0016740 | molecular_function | transferase activity |
| I | 0046872 | molecular_function | metal ion binding |
| I | 0051923 | biological_process | sulfation |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0008146 | molecular_function | sulfotransferase activity |
| J | 0016740 | molecular_function | transferase activity |
| J | 0046872 | molecular_function | metal ion binding |
| J | 0051923 | biological_process | sulfation |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0008146 | molecular_function | sulfotransferase activity |
| K | 0016740 | molecular_function | transferase activity |
| K | 0046872 | molecular_function | metal ion binding |
| K | 0051923 | biological_process | sulfation |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0008146 | molecular_function | sulfotransferase activity |
| L | 0016740 | molecular_function | transferase activity |
| L | 0046872 | molecular_function | metal ion binding |
| L | 0051923 | biological_process | sulfation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue A3P C 301 |
| Chain | Residue |
| C | LYS47 |
| C | THR213 |
| C | PHE215 |
| C | MET218 |
| C | VAL243 |
| C | PHE244 |
| C | ARG245 |
| C | LYS246 |
| C | GLY247 |
| C | HOH434 |
| C | HOH436 |
| C | SER48 |
| C | HOH451 |
| C | GLY49 |
| C | THR50 |
| C | HIS51 |
| C | TRP52 |
| C | ARG116 |
| C | SER124 |
| C | TYR179 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 302 |
| Chain | Residue |
| A | LYS169 |
| A | ASP171 |
| A | VAL174 |
| A | HOH523 |
| C | GLU167 |
| C | HOH456 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue A3P A 301 |
| Chain | Residue |
| A | LYS47 |
| A | SER48 |
| A | GLY49 |
| A | THR50 |
| A | HIS51 |
| A | TRP52 |
| A | ARG116 |
| A | SER124 |
| A | TYR179 |
| A | LYS183 |
| A | THR213 |
| A | PHE215 |
| A | MET218 |
| A | VAL243 |
| A | ARG245 |
| A | LYS246 |
| A | GLY247 |
| A | HOH403 |
| A | HOH412 |
| A | HOH449 |
| A | HOH470 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 302 |
| Chain | Residue |
| A | GLU98 |
| A | HOH429 |
| A | HOH467 |
| A | HOH528 |
| B | ASP160 |
| B | HOH471 |
| B | HOH514 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 303 |
| Chain | Residue |
| A | ASP120 |
| A | VAL248 |
| A | GLY250 |
| A | ASP251 |
| A | HOH449 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | binding site for residue A3P B 301 |
| Chain | Residue |
| B | LYS47 |
| B | SER48 |
| B | GLY49 |
| B | THR50 |
| B | HIS51 |
| B | TRP52 |
| B | ARG116 |
| B | SER124 |
| B | TYR179 |
| B | THR213 |
| B | SER214 |
| B | PHE215 |
| B | MET218 |
| B | VAL243 |
| B | PHE244 |
| B | ARG245 |
| B | LYS246 |
| B | GLY247 |
| B | HOH420 |
| B | HOH475 |
| B | HOH491 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue CA B 302 |
| Chain | Residue |
| A | HOH425 |
| A | HOH464 |
| B | GLU98 |
| B | MET99 |
| B | HOH403 |
| B | HOH459 |
| B | HOH470 |
| B | HOH526 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 303 |
| Chain | Residue |
| B | HIS94 |
| B | ASN96 |
| B | TYR155 |
| B | HIS161 |
| B | HOH444 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 304 |
| Chain | Residue |
| B | TYR129 |
| B | ASN132 |
| B | PRO133 |
| B | LEU135 |
| D | ARG211 |
| D | HOH429 |
| site_id | AD1 |
| Number of Residues | 23 |
| Details | binding site for residue A3P D 301 |
| Chain | Residue |
| D | LYS47 |
| D | SER48 |
| D | GLY49 |
| D | THR50 |
| D | HIS51 |
| D | TRP52 |
| D | ARG116 |
| D | SER124 |
| D | TYR179 |
| D | LYS183 |
| D | THR213 |
| D | PHE215 |
| D | MET218 |
| D | VAL243 |
| D | PHE244 |
| D | ARG245 |
| D | LYS246 |
| D | GLY247 |
| D | HOH466 |
| D | HOH472 |
| D | HOH491 |
| D | HOH501 |
| D | HOH506 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 302 |
| Chain | Residue |
| D | GLU98 |
| D | HOH440 |
| D | HOH442 |
| E | HOH494 |
| E | HOH518 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 303 |
| Chain | Residue |
| D | LYS169 |
| D | ASP171 |
| D | VAL174 |
| F | GLU167 |
| F | HOH464 |
| F | HOH499 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 304 |
| Chain | Residue |
| D | ARG36 |
| D | ASP38 |
| D | ASP39 |
| D | LYS87 |
| D | ARG88 |
| D | ARG89 |
| site_id | AD5 |
| Number of Residues | 20 |
| Details | binding site for residue A3P E 301 |
| Chain | Residue |
| E | LYS47 |
| E | SER48 |
| E | GLY49 |
| E | THR50 |
| E | HIS51 |
| E | TRP52 |
| E | ARG116 |
| E | SER124 |
| E | TYR179 |
| E | THR213 |
| E | SER214 |
| E | PHE215 |
| E | MET218 |
| E | VAL243 |
| E | PHE244 |
| E | ARG245 |
| E | LYS246 |
| E | GLY247 |
| E | HOH433 |
| E | HOH480 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue CA E 302 |
| Chain | Residue |
| D | HOH450 |
| D | HOH486 |
| E | GLU98 |
| E | HOH423 |
| E | HOH446 |
| E | HOH458 |
| site_id | AD7 |
| Number of Residues | 21 |
| Details | binding site for residue A3P F 301 |
| Chain | Residue |
| F | LYS47 |
| F | SER48 |
| F | GLY49 |
| F | THR50 |
| F | HIS51 |
| F | TRP52 |
| F | ARG116 |
| F | SER124 |
| F | TYR179 |
| F | THR213 |
| F | PHE215 |
| F | MET218 |
| F | VAL243 |
| F | PHE244 |
| F | ARG245 |
| F | LYS246 |
| F | GLY247 |
| F | HOH425 |
| F | HOH432 |
| F | HOH437 |
| F | HOH445 |
| site_id | AD8 |
| Number of Residues | 11 |
| Details | binding site for residue CA F 302 |
| Chain | Residue |
| F | ASP31 |
| F | GLU98 |
| F | MET99 |
| F | LEU100 |
| F | PRO101 |
| F | VAL102 |
| F | LYS105 |
| F | HOH420 |
| F | HOH435 |
| F | HOH439 |
| F | HOH443 |
| site_id | AD9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL F 303 |
| Chain | Residue |
| F | TYR13 |
| F | GLY28 |
| site_id | AE1 |
| Number of Residues | 22 |
| Details | binding site for residue A3P G 301 |
| Chain | Residue |
| G | PRO46 |
| G | LYS47 |
| G | SER48 |
| G | GLY49 |
| G | THR50 |
| G | HIS51 |
| G | TRP52 |
| G | ARG116 |
| G | SER124 |
| G | TYR179 |
| G | LYS183 |
| G | THR213 |
| G | SER214 |
| G | PHE215 |
| G | MET218 |
| G | VAL243 |
| G | ARG245 |
| G | LYS246 |
| G | GLY247 |
| G | HOH430 |
| G | HOH454 |
| G | HOH463 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue CA G 302 |
| Chain | Residue |
| G | GLU98 |
| G | HOH472 |
| G | HOH527 |
| G | HOH529 |
| I | HOH467 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue CA G 303 |
| Chain | Residue |
| G | LYS169 |
| G | ASP171 |
| G | VAL174 |
| G | HOH489 |
| H | GLU167 |
| H | HOH434 |
| H | HOH458 |
| site_id | AE4 |
| Number of Residues | 20 |
| Details | binding site for residue A3P H 301 |
| Chain | Residue |
| H | LYS47 |
| H | SER48 |
| H | GLY49 |
| H | THR50 |
| H | HIS51 |
| H | TRP52 |
| H | ARG116 |
| H | SER124 |
| H | TYR179 |
| H | LYS183 |
| H | THR213 |
| H | SER214 |
| H | PHE215 |
| H | MET218 |
| H | VAL243 |
| H | ARG245 |
| H | LYS246 |
| H | GLY247 |
| H | HOH405 |
| H | HOH481 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue CA H 302 |
| Chain | Residue |
| H | GLU98 |
| H | HOH445 |
| H | HOH488 |
| H | HOH516 |
| site_id | AE6 |
| Number of Residues | 19 |
| Details | binding site for residue A3P I 301 |
| Chain | Residue |
| I | LYS47 |
| I | SER48 |
| I | GLY49 |
| I | THR50 |
| I | HIS51 |
| I | TRP52 |
| I | ARG116 |
| I | SER124 |
| I | TYR179 |
| I | THR213 |
| I | PHE215 |
| I | MET218 |
| I | VAL243 |
| I | PHE244 |
| I | ARG245 |
| I | LYS246 |
| I | GLY247 |
| I | HOH427 |
| I | HOH440 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue CA I 302 |
| Chain | Residue |
| G | HOH542 |
| I | GLU98 |
| I | HOH431 |
| site_id | AE8 |
| Number of Residues | 22 |
| Details | binding site for residue A3P J 301 |
| Chain | Residue |
| J | PRO46 |
| J | LYS47 |
| J | SER48 |
| J | GLY49 |
| J | THR50 |
| J | HIS51 |
| J | TRP52 |
| J | ARG116 |
| J | SER124 |
| J | TYR179 |
| J | THR213 |
| J | PHE215 |
| J | MET218 |
| J | VAL243 |
| J | ARG245 |
| J | LYS246 |
| J | GLY247 |
| J | HOH408 |
| J | HOH421 |
| J | HOH456 |
| J | HOH464 |
| J | HOH489 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue CA J 302 |
| Chain | Residue |
| J | ASP31 |
| J | GLU98 |
| J | LEU100 |
| J | HOH439 |
| J | HOH452 |
| J | HOH459 |
| site_id | AF1 |
| Number of Residues | 9 |
| Details | binding site for residue CA J 303 |
| Chain | Residue |
| G | ARG211 |
| J | TYR128 |
| J | TYR129 |
| J | ARG130 |
| J | ASP131 |
| J | ASN132 |
| J | LEU135 |
| J | SER137 |
| J | HOH431 |
| site_id | AF2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL J 304 |
| Chain | Residue |
| J | SER137 |
| J | GLU139 |
| site_id | AF3 |
| Number of Residues | 24 |
| Details | binding site for residue A3P K 301 |
| Chain | Residue |
| K | LYS47 |
| K | SER48 |
| K | GLY49 |
| K | THR50 |
| K | HIS51 |
| K | TRP52 |
| K | ARG116 |
| K | SER124 |
| K | TYR179 |
| K | LYS183 |
| K | THR213 |
| K | SER214 |
| K | PHE215 |
| K | MET218 |
| K | VAL243 |
| K | PHE244 |
| K | ARG245 |
| K | LYS246 |
| K | GLY247 |
| K | HOH405 |
| K | HOH411 |
| K | HOH451 |
| K | HOH492 |
| K | HOH501 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue CA K 302 |
| Chain | Residue |
| K | LYS169 |
| K | ASP171 |
| K | VAL174 |
| L | GLU167 |
| L | HOH415 |
| site_id | AF5 |
| Number of Residues | 7 |
| Details | binding site for residue CA K 303 |
| Chain | Residue |
| J | HOH539 |
| K | ASP31 |
| K | GLU98 |
| K | HOH408 |
| K | HOH426 |
| K | HOH444 |
| K | HOH508 |
| site_id | AF6 |
| Number of Residues | 24 |
| Details | binding site for residue A3P L 301 |
| Chain | Residue |
| L | TYR45 |
| L | PRO46 |
| L | LYS47 |
| L | SER48 |
| L | GLY49 |
| L | THR50 |
| L | HIS51 |
| L | TRP52 |
| L | ARG116 |
| L | SER124 |
| L | TYR179 |
| L | LYS183 |
| L | THR213 |
| L | SER214 |
| L | PHE215 |
| L | MET218 |
| L | VAL243 |
| L | PHE244 |
| L | ARG245 |
| L | LYS246 |
| L | GLY247 |
| L | HOH406 |
| L | HOH419 |
| L | HOH457 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue CA L 302 |
| Chain | Residue |
| L | GLU37 |
| L | GLN106 |
| L | LYS107 |
| L | HOH430 |
| L | HOH496 |
