Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5WYF

Structure of amino acid racemase, 2.12 A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008483	molecular_function	transaminase activity
A	0016853	molecular_function	isomerase activity
A	0030170	molecular_function	pyridoxal phosphate binding
B	0008483	molecular_function	transaminase activity
B	0016853	molecular_function	isomerase activity
B	0030170	molecular_function	pyridoxal phosphate binding
C	0008483	molecular_function	transaminase activity
C	0016853	molecular_function	isomerase activity
C	0030170	molecular_function	pyridoxal phosphate binding
D	0008483	molecular_function	transaminase activity
D	0016853	molecular_function	isomerase activity
D	0030170	molecular_function	pyridoxal phosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	binding site for residue ILP A 1001

Chain	Residue
A	ALA54
A	VAL252
A	ASN253
A	LYS280
A	ARG408
A	HOH1117
A	HOH1155
A	HOH1167
B	ALA83
B	TYR84
B	PHE308
A	SER114
B	THR309
B	HOH1119
A	GLY115
A	SER116
A	TYR142
A	HIS143
A	GLU217
A	ASP222
A	ASP250

site_id	AC2
Number of Residues	3
Details	binding site for residue CD A 1002

Chain	Residue
A	ASP5
A	HIS241
A	ASP274

site_id	AC3
Number of Residues	2
Details	binding site for residue CD A 1003

Chain	Residue
A	HIS33
A	HOH1222

site_id	AC4
Number of Residues	2
Details	binding site for residue CD A 1004

Chain	Residue
A	HIS35
A	HOH1221

site_id	AC5
Number of Residues	2
Details	binding site for residue CD A 1005

Chain	Residue
A	GLU64
A	HOH1223

site_id	AC6
Number of Residues	2
Details	binding site for residue CD A 1006

Chain	Residue
A	HIS188
A	GLU231

site_id	AC7
Number of Residues	2
Details	binding site for residue CD A 1007

Chain	Residue
A	HIS243
A	HOH1216

site_id	AC8
Number of Residues	4
Details	binding site for residue CD A 1008

Chain	Residue
A	ARG353
A	HIS354
A	GLU435
A	HOH1218

site_id	AC9
Number of Residues	1
Details	binding site for residue CD A 1009

Chain	Residue
A	ASP381

site_id	AD1
Number of Residues	1
Details	binding site for residue CD A 1010

Chain	Residue
A	HIS395

site_id	AD2
Number of Residues	2
Details	binding site for residue CD A 1011

Chain	Residue
A	GLU95
B	GLU13

site_id	AD3
Number of Residues	19
Details	binding site for residue ILP B 1001

Chain	Residue
A	ALA83
A	TYR84
A	THR309
B	ALA54
B	SER114
B	GLY115
B	SER116
B	TYR142
B	HIS143
B	GLU217
B	ASP222
B	ASP250
B	ASN253
B	LYS280
B	ARG408
B	HOH1122
B	HOH1129
B	HOH1143
B	HOH1170

site_id	AD4
Number of Residues	2
Details	binding site for residue CD B 1002

Chain	Residue
A	GLU13
B	GLU95

site_id	AD5
Number of Residues	1
Details	binding site for residue CD B 1003

Chain	Residue
B	HIS33

site_id	AD6
Number of Residues	2
Details	binding site for residue CD B 1004

Chain	Residue
B	HIS35
B	GLU64

site_id	AD7
Number of Residues	2
Details	binding site for residue CD B 1005

Chain	Residue
B	HIS188
B	GLU231

site_id	AD8
Number of Residues	1
Details	binding site for residue CD B 1006

Chain	Residue
B	HIS243

site_id	AD9
Number of Residues	3
Details	binding site for residue CD B 1007

Chain	Residue
B	ARG353
B	HIS354
B	GLU435

site_id	AE1
Number of Residues	3
Details	binding site for residue CD B 1008

Chain	Residue
B	ASP381
B	HOH1124
B	HOH1206

site_id	AE2
Number of Residues	1
Details	binding site for residue CD B 1009

Chain	Residue
B	GLU418

site_id	AE3
Number of Residues	21
Details	binding site for residue ILP C 1001

Chain	Residue
C	ALA54
C	SER114
C	GLY115
C	SER116
C	TYR142
C	HIS143
C	GLU217
C	ASP222
C	ASP250
C	VAL252
C	ASN253
C	LYS280
C	ARG408
C	HOH1133
C	HOH1138
C	HOH1147
D	ALA83
D	TYR84
D	PHE308
D	THR309
D	HOH1110

site_id	AE4
Number of Residues	2
Details	binding site for residue CD C 1002

Chain	Residue
C	HIS33
C	HOH1194

site_id	AE5
Number of Residues	2
Details	binding site for residue CD C 1003

Chain	Residue
C	HIS35
C	GLU64

site_id	AE6
Number of Residues	3
Details	binding site for residue CD C 1004

Chain	Residue
C	HIS188
C	GLU231
C	HOH1196

site_id	AE7
Number of Residues	4
Details	binding site for residue CD C 1005

Chain	Residue
C	ASP5
C	HIS241
C	ASP274
C	HOH1192

site_id	AE8
Number of Residues	1
Details	binding site for residue CD C 1006

Chain	Residue
C	HIS243

site_id	AE9
Number of Residues	3
Details	binding site for residue CD C 1007

Chain	Residue
C	ARG353
C	HIS354
C	GLU435

site_id	AF1
Number of Residues	1
Details	binding site for residue CD C 1008

Chain	Residue
C	ASP381

site_id	AF2
Number of Residues	1
Details	binding site for residue CD C 1009

Chain	Residue
C	HIS395

site_id	AF3
Number of Residues	3
Details	binding site for residue CD C 1010

Chain	Residue
C	GLU95
C	HOH1124
D	GLU13

site_id	AF4
Number of Residues	1
Details	binding site for residue CD C 1011

Chain	Residue
C	GLU328

site_id	AF5
Number of Residues	19
Details	binding site for residue ILP D 1001

Chain	Residue
C	ALA83
C	TYR84
C	PHE308
C	THR309
D	ALA54
D	SER114
D	GLY115
D	SER116
D	TYR142
D	HIS143
D	GLU217
D	ASP222
D	ASP250
D	VAL252
D	ASN253
D	LYS280
D	ARG408
D	HOH1116
D	HOH1118

site_id	AF6
Number of Residues	1
Details	binding site for residue CD D 1002

Chain	Residue
D	HIS33

site_id	AF7
Number of Residues	2
Details	binding site for residue CD D 1003

Chain	Residue
D	HIS35
D	GLU64

site_id	AF8
Number of Residues	3
Details	binding site for residue CD D 1004

Chain	Residue
D	HIS188
D	GLU231
D	HOH1177

site_id	AF9
Number of Residues	1
Details	binding site for residue CD D 1005

Chain	Residue
D	HIS243

site_id	AG1
Number of Residues	3
Details	binding site for residue CD D 1006

Chain	Residue
D	ARG353
D	HIS354
D	GLU435

site_id	AG2
Number of Residues	1
Details	binding site for residue CD D 1007

Chain	Residue
D	ASP381

site_id	AG3
Number of Residues	1
Details	binding site for residue CD D 1008

Chain	Residue
D	HIS395

site_id	AG4
Number of Residues	2
Details	binding site for residue CD D 1009

Chain	Residue
C	GLU13
D	GLU95

Functional Information from PROSITE/UniProt

site_id	PS00600
Number of Residues	39
Details	AA_TRANSFER_CLASS_3 Aminotransferases class-III pyridoxal-phosphate attachment site. FAiDEVnq.GLgRtGkmwaiqqfkdiep...DLMsvGKslaSG

Chain	Residue	Details
A	PHE247-GLY285

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P22256

Chain	Residue	Details
A	GLY115
C	TYR142
C	ASP250
C	THR309
D	GLY115
D	TYR142
D	ASP250
D	THR309
A	TYR142
A	ASP250
A	THR309
B	GLY115
B	TYR142
B	ASP250
B	THR309
C	GLY115

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000250\|UniProtKB:P22256

Chain	Residue	Details
A	LYS280
B	LYS280
C	LYS280
D	LYS280

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)