5WWT

Crystal structure of human NSun6/tRNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0001510	biological_process	RNA methylation
A	0002946	biological_process	tRNA C5-cytosine methylation
A	0003723	molecular_function	RNA binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006396	biological_process	RNA processing
A	0006400	biological_process	tRNA modification
A	0008168	molecular_function	methyltransferase activity
A	0008173	molecular_function	RNA methyltransferase activity
A	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
A	0016428	molecular_function	tRNA (cytidine-5-)-methyltransferase activity
A	0030488	biological_process	tRNA methylation
A	0032259	biological_process	methylation
B	0000049	molecular_function	tRNA binding
B	0001510	biological_process	RNA methylation
B	0002946	biological_process	tRNA C5-cytosine methylation
B	0003723	molecular_function	RNA binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006396	biological_process	RNA processing
B	0006400	biological_process	tRNA modification
B	0008168	molecular_function	methyltransferase activity
B	0008173	molecular_function	RNA methyltransferase activity
B	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
B	0016428	molecular_function	tRNA (cytidine-5-)-methyltransferase activity
B	0030488	biological_process	tRNA methylation
B	0032259	biological_process	methylation

Functional Information from PROSITE/UniProt

site_id	PS01153
Number of Residues	12
Details	NOL1_NOP2_SUN NOL1/NOP2/sun family signature. FDRILlDAPCSG

Chain	Residue	Details
A	PHE317-GLY328

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU01023, ECO:0000269|PubMed:28531330, ECO:0007744|PDB:5WWS

Chain	Residue	Details
A	CYS373
B	CYS373

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01023, ECO:0000269|PubMed:28531330, ECO:0007744|PDB:5WWS

Chain	Residue	Details
A	CYS242
A	ASP266
A	ASP323
B	CYS242
B	ASP266
B	ASP323

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01023

Chain	Residue	Details
A	ASP293
B	ASP293

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS419
B	LYS419

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