5WWD
Crystal structure of AtNUDX1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000210 | molecular_function | NAD+ diphosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006203 | biological_process | dGTP catabolic process |
| A | 0006950 | biological_process | response to stress |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019177 | molecular_function | dihydroneopterin triphosphate pyrophosphohydrolase activity |
| A | 0035529 | molecular_function | NADH pyrophosphatase activity |
| A | 0035539 | molecular_function | 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000210 | molecular_function | NAD+ diphosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006203 | biological_process | dGTP catabolic process |
| B | 0006950 | biological_process | response to stress |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019177 | molecular_function | dihydroneopterin triphosphate pyrophosphohydrolase activity |
| B | 0035529 | molecular_function | NADH pyrophosphatase activity |
| B | 0035539 | molecular_function | 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 201 |
| Chain | Residue |
| A | ASN105 |
| A | GLY113 |
| A | TRP114 |
| A | HOH303 |
| A | HOH379 |
| B | LYS104 |
| B | ASN105 |
| B | HOH347 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 2ME A 202 |
| Chain | Residue |
| A | VAL77 |
| A | TRP128 |
| A | LYS132 |
| A | HOH333 |
| A | ASN75 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue NH4 A 203 |
| Chain | Residue |
| A | SER89 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 204 |
| Chain | Residue |
| A | GLY41 |
| A | HIS42 |
| A | MG205 |
| A | HOH342 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 205 |
| Chain | Residue |
| A | GLU56 |
| A | MG204 |
| A | MG206 |
| A | HOH302 |
| A | HOH342 |
| A | HOH365 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 206 |
| Chain | Residue |
| A | GLU56 |
| A | GLU59 |
| A | GLU60 |
| A | GLU107 |
| A | MG205 |
| A | HOH342 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 201 |
| Chain | Residue |
| A | ASN20 |
| A | TRP119 |
| A | GLU120 |
| A | ASN139 |
| A | PHE141 |
| B | TRP119 |
| B | GLU120 |
| B | GOL203 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 202 |
| Chain | Residue |
| B | ARG28 |
| B | SER34 |
| B | GLU112 |
| B | HOH302 |
| B | HOH315 |
| B | HOH322 |
| B | HOH346 |
| B | HOH407 |
| B | HOH417 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 203 |
| Chain | Residue |
| A | TRP119 |
| A | GLU120 |
| B | ASN20 |
| B | TRP119 |
| B | ASN139 |
| B | PHE141 |
| B | GOL201 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 204 |
| Chain | Residue |
| B | GLU56 |
| B | MG205 |
| B | HOH363 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 205 |
| Chain | Residue |
| B | GLY41 |
| B | HIS42 |
| B | MG204 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 206 |
| Chain | Residue |
| B | GLU56 |
| B | GLU59 |
| B | GLU107 |
| B | LYS110 |
Functional Information from PROSITE/UniProt
| site_id | PS00893 |
| Number of Residues | 22 |
| Details | NUDIX_BOX Nudix box signature. GhlefgEsfeeCAaREVmEEtG |
| Chain | Residue | Details |
| A | GLY41-GLY62 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 266 |
| Details | Domain: {"description":"Nudix hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Motif: {"description":"Nudix box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
