5WRL
Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00990 |
| Number of Residues | 21 |
| Details | CLAT_ADAPTOR_M_1 Clathrin adaptor complexes medium chain signature 1. IGWRre.GikYrrNeLFLDVLE |
| Chain | Residue | Details |
| A | ILE159-GLU179 |
| site_id | PS00991 |
| Number of Residues | 15 |
| Details | CLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. IsFIPPdGeFeLmrY |
| Chain | Residue | Details |
| A | ILE263-TYR277 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12086608","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25061211","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2VGL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UQI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"YXXM motif 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by INSR","evidences":[{"source":"PubMed","id":"7504175","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by RPS6KB1 and ROCK2","evidences":[{"source":"UniProtKB","id":"P35569","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
