5WQP
Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 in complex with NADP (condition II)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004090 | molecular_function | carbonyl reductase (NADPH) activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004090 | molecular_function | carbonyl reductase (NADPH) activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 33 |
| Details | binding site for residue NAP A 301 |
| Chain | Residue |
| A | SER10 |
| A | GLY85 |
| A | MET133 |
| A | SER134 |
| A | TYR151 |
| A | LYS155 |
| A | PRO181 |
| A | GLY182 |
| A | TRP183 |
| A | VAL184 |
| A | THR186 |
| A | ARG11 |
| A | MET188 |
| A | NCA302 |
| A | HOH412 |
| A | HOH414 |
| A | HOH433 |
| A | HOH437 |
| A | HOH453 |
| A | HOH470 |
| A | HOH475 |
| A | HOH479 |
| A | ILE13 |
| A | HOH481 |
| A | HOH495 |
| A | HOH500 |
| A | HOH502 |
| A | ARG33 |
| A | ASP58 |
| A | LEU59 |
| A | ASN60 |
| A | ASN83 |
| A | ALA84 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue NCA A 302 |
| Chain | Residue |
| A | SER135 |
| A | GLN136 |
| A | MET148 |
| A | TYR151 |
| A | HIS180 |
| A | TRP183 |
| A | MET188 |
| A | NAP301 |
| B | GLU199 |
| B | HOH410 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 303 |
| Chain | Residue |
| A | ARG11 |
| A | GLY12 |
| A | GLU187 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 B 301 |
| Chain | Residue |
| B | LEU59 |
| B | GLN61 |
| B | HIS62 |
| B | ASP63 |
| B | CYS64 |
| B | ALA65 |
| B | ARG115 |
| B | LEU116 |
| B | HOH435 |
