5WQH

Structure of fungal meroterpenoid isomerase Trt14 complexed with substrate analog and endo-terretonin D

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016114	biological_process	terpenoid biosynthetic process
A	0016853	molecular_function	isomerase activity
B	0016114	biological_process	terpenoid biosynthetic process
B	0016853	molecular_function	isomerase activity
C	0016114	biological_process	terpenoid biosynthetic process
C	0016853	molecular_function	isomerase activity
D	0016114	biological_process	terpenoid biosynthetic process
D	0016853	molecular_function	isomerase activity
E	0016114	biological_process	terpenoid biosynthetic process
E	0016853	molecular_function	isomerase activity
F	0016114	biological_process	terpenoid biosynthetic process
F	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CA A 201

Chain	Residue
A	ASN59
A	GLU62
A	HOH360
A	HOH362

---

site_id	AC2
Number of Residues	1
Details	binding site for residue CA A 202

Chain	Residue
A	HOH368

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CA A 203

Chain	Residue
A	GLU134
A	ASP138
A	HOH370

---

site_id	AC4
Number of Residues	14
Details	binding site for residue 7WU A 204

Chain	Residue
A	TYR19
A	PHE22
A	ARG31
A	SER37
A	ARG39
A	ARG48
A	SER53
A	ALA56
A	LEU67
A	TRP101
A	ILE121
A	PHE125
A	HOH349
A	PHE15

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CA B 201

Chain	Residue
B	GLU134
B	ASP138
B	HOH373
B	HOH381

---

site_id	AC6
Number of Residues	15
Details	binding site for residue 7WU B 202

Chain	Residue
B	TYR19
B	PHE22
B	ARG31
B	SER37
B	ARG39
B	ARG48
B	SER53
B	ALA56
B	CYS57
B	PHE64
B	TRP101
B	PHE125
B	HOH319
B	HOH341
B	HOH368

---

site_id	AC7
Number of Residues	15
Details	binding site for residue 7WU C 201

Chain	Residue
C	TYR19
C	PHE22
C	SER37
C	ARG39
C	ARG48
C	SER53
C	ALA56
C	CYS57
C	ALA60
C	PHE64
C	LEU67
C	TRP101
C	PHE125
C	HOH314
F	PHE142

---

site_id	AC8
Number of Residues	7
Details	binding site for residue 7WX D 201

Chain	Residue
D	TYR19
D	SER37
D	ARG39
D	ARG48
D	TRP101
D	PHE125
D	HOH330

---

site_id	AC9
Number of Residues	12
Details	binding site for residue 7WX E 201

Chain	Residue
E	TYR19
E	ILE27
E	SER37
E	ARG39
E	ARG48
E	SER53
E	ALA60
E	PHE64
E	TRP101
E	PHE125
E	HOH310
E	HOH316

---

site_id	AD1
Number of Residues	1
Details	binding site for residue CA E 202

Chain	Residue
E	ASP138

---

site_id	AD2
Number of Residues	1
Details	binding site for residue CA F 201

Chain	Residue
F	ASP74

---

site_id	AD3
Number of Residues	5
Details	binding site for residue CA F 202

Chain	Residue
C	ASP138
F	ASP138
F	HOH316
F	HOH345
F	HOH352

---

site_id	AD4
Number of Residues	15
Details	binding site for residue 7WU F 203

Chain	Residue
C	PHE142
F	TYR19
F	ILE27
F	ARG31
F	SER37
F	ARG39
F	ARG48
F	SER53
F	CYS57
F	LEU67
F	TRP101
F	PHE107
F	PHE125
F	MET130
F	HOH324

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0007744|PDB:5WQH, ECO:0007744|PDB:5WQI

Chain	Residue	Details
A	TYR19
B	TYR19
C	TYR19
D	TYR19
E	TYR19
F	TYR19

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0007744|PDB:5WQI

Chain	Residue	Details
A	ARG39
B	ARG39
C	ARG39
D	ARG39
E	ARG39
F	ARG39

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0007744|PDB:5WQG, ECO:0007744|PDB:5WQH, ECO:0007744|PDB:5WQI

Chain	Residue	Details
A	ARG48
B	ARG48
C	ARG48
D	ARG48
E	ARG48
F	ARG48

---