5WQ2
Crystal structure of 3C protease from a mild Human enterovirus 71 in complex with rupintrivir
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019028 | cellular_component | viral capsid |
| A | 0019062 | biological_process | virion attachment to host cell |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0039618 | cellular_component | T=pseudo3 icosahedral viral capsid |
| A | 0044423 | cellular_component | virion component |
| A | 0046718 | biological_process | symbiont entry into host cell |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue AG7 A 301 |
| Chain | Residue |
| A | GLN43 |
| A | LYS151 |
| A | THR163 |
| A | LYS164 |
| A | ALA165 |
| A | GLY166 |
| A | CYS168 |
| A | HIS182 |
| A | ILE183 |
| A | GLY184 |
| A | GLY185 |
| A | PHE46 |
| A | ASN186 |
| A | PHE191 |
| A | SO4303 |
| A | HOH421 |
| A | HOH461 |
| A | HIS61 |
| A | GLU92 |
| A | TYR143 |
| A | LEU146 |
| A | ASN147 |
| A | LEU148 |
| A | SER149 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | ASN76 |
| A | LYS196 |
| A | SER198 |
| A | HOH476 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG60 |
| A | HIS61 |
| A | GLN63 |
| A | LYS151 |
| A | AG7301 |
| A | HOH421 |
