5WP9

Structural Basis of Mitochondrial Receptor Binding and Constriction by Dynamin-Related Protein 1

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000266	biological_process	mitochondrial fission
A	0003924	molecular_function	GTPase activity
A	0005096	molecular_function	GTPase activator activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005741	cellular_component	mitochondrial outer membrane
A	0005777	cellular_component	peroxisome
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0005874	cellular_component	microtubule
A	0005903	cellular_component	brush border
A	0005905	cellular_component	clathrin-coated pit
A	0006816	biological_process	calcium ion transport
A	0006897	biological_process	endocytosis
A	0007005	biological_process	mitochondrion organization
A	0007029	biological_process	endoplasmic reticulum organization
A	0008017	molecular_function	microtubule binding
A	0008289	molecular_function	lipid binding
A	0010468	biological_process	regulation of gene expression
A	0010821	biological_process	regulation of mitochondrion organization
A	0012501	biological_process	programmed cell death
A	0012505	cellular_component	endomembrane system
A	0016020	cellular_component	membrane
A	0016559	biological_process	peroxisome fission
A	0016787	molecular_function	hydrolase activity
A	0030672	cellular_component	synaptic vesicle membrane
A	0030742	molecular_function	GTP-dependent protein binding
A	0031267	molecular_function	small GTPase binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0043653	biological_process	mitochondrial fragmentation involved in apoptotic process
A	0048312	biological_process	intracellular distribution of mitochondria
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0048511	biological_process	rhythmic process
A	0050714	biological_process	positive regulation of protein secretion
A	0051259	biological_process	protein complex oligomerization
A	0060047	biological_process	heart contraction
A	0070585	biological_process	protein localization to mitochondrion
A	0090023	biological_process	positive regulation of neutrophil chemotaxis
A	0090141	biological_process	positive regulation of mitochondrial fission
A	0090149	biological_process	mitochondrial membrane fission
A	0099073	cellular_component	mitochondrion-derived vesicle
A	0160040	biological_process	mitocytosis
A	1900063	biological_process	regulation of peroxisome organization
A	1901524	biological_process	regulation of mitophagy
A	1903532	biological_process	positive regulation of secretion by cell
A	1903578	biological_process	regulation of ATP metabolic process
B	0005741	cellular_component	mitochondrial outer membrane
B	0007005	biological_process	mitochondrion organization
C	0000166	molecular_function	nucleotide binding
C	0000266	biological_process	mitochondrial fission
C	0003924	molecular_function	GTPase activity
C	0005096	molecular_function	GTPase activator activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005741	cellular_component	mitochondrial outer membrane
C	0005777	cellular_component	peroxisome
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005794	cellular_component	Golgi apparatus
C	0005829	cellular_component	cytosol
C	0005874	cellular_component	microtubule
C	0005903	cellular_component	brush border
C	0005905	cellular_component	clathrin-coated pit
C	0006816	biological_process	calcium ion transport
C	0006897	biological_process	endocytosis
C	0007005	biological_process	mitochondrion organization
C	0007029	biological_process	endoplasmic reticulum organization
C	0008017	molecular_function	microtubule binding
C	0008289	molecular_function	lipid binding
C	0010468	biological_process	regulation of gene expression
C	0010821	biological_process	regulation of mitochondrion organization
C	0012501	biological_process	programmed cell death
C	0012505	cellular_component	endomembrane system
C	0016020	cellular_component	membrane
C	0016559	biological_process	peroxisome fission
C	0016787	molecular_function	hydrolase activity
C	0030672	cellular_component	synaptic vesicle membrane
C	0030742	molecular_function	GTP-dependent protein binding
C	0031267	molecular_function	small GTPase binding
C	0031410	cellular_component	cytoplasmic vesicle
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0043653	biological_process	mitochondrial fragmentation involved in apoptotic process
C	0048312	biological_process	intracellular distribution of mitochondria
C	0048471	cellular_component	perinuclear region of cytoplasm
C	0048511	biological_process	rhythmic process
C	0050714	biological_process	positive regulation of protein secretion
C	0051259	biological_process	protein complex oligomerization
C	0060047	biological_process	heart contraction
C	0070585	biological_process	protein localization to mitochondrion
C	0090023	biological_process	positive regulation of neutrophil chemotaxis
C	0090141	biological_process	positive regulation of mitochondrial fission
C	0090149	biological_process	mitochondrial membrane fission
C	0099073	cellular_component	mitochondrion-derived vesicle
C	0160040	biological_process	mitocytosis
C	1900063	biological_process	regulation of peroxisome organization
C	1901524	biological_process	regulation of mitophagy
C	1903532	biological_process	positive regulation of secretion by cell
C	1903578	biological_process	regulation of ATP metabolic process
D	0005741	cellular_component	mitochondrial outer membrane
D	0007005	biological_process	mitochondrion organization
E	0000166	molecular_function	nucleotide binding
E	0000266	biological_process	mitochondrial fission
E	0003924	molecular_function	GTPase activity
E	0005096	molecular_function	GTPase activator activity
E	0005515	molecular_function	protein binding
E	0005525	molecular_function	GTP binding
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005741	cellular_component	mitochondrial outer membrane
E	0005777	cellular_component	peroxisome
E	0005783	cellular_component	endoplasmic reticulum
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005794	cellular_component	Golgi apparatus
E	0005829	cellular_component	cytosol
E	0005874	cellular_component	microtubule
E	0005903	cellular_component	brush border
E	0005905	cellular_component	clathrin-coated pit
E	0006816	biological_process	calcium ion transport
E	0006897	biological_process	endocytosis
E	0007005	biological_process	mitochondrion organization
E	0007029	biological_process	endoplasmic reticulum organization
E	0008017	molecular_function	microtubule binding
E	0008289	molecular_function	lipid binding
E	0010468	biological_process	regulation of gene expression
E	0010821	biological_process	regulation of mitochondrion organization
E	0012501	biological_process	programmed cell death
E	0012505	cellular_component	endomembrane system
E	0016020	cellular_component	membrane
E	0016559	biological_process	peroxisome fission
E	0016787	molecular_function	hydrolase activity
E	0030672	cellular_component	synaptic vesicle membrane
E	0030742	molecular_function	GTP-dependent protein binding
E	0031267	molecular_function	small GTPase binding
E	0031410	cellular_component	cytoplasmic vesicle
E	0031625	molecular_function	ubiquitin protein ligase binding
E	0032991	cellular_component	protein-containing complex
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0043653	biological_process	mitochondrial fragmentation involved in apoptotic process
E	0048312	biological_process	intracellular distribution of mitochondria
E	0048471	cellular_component	perinuclear region of cytoplasm
E	0048511	biological_process	rhythmic process
E	0050714	biological_process	positive regulation of protein secretion
E	0051259	biological_process	protein complex oligomerization
E	0060047	biological_process	heart contraction
E	0070585	biological_process	protein localization to mitochondrion
E	0090023	biological_process	positive regulation of neutrophil chemotaxis
E	0090141	biological_process	positive regulation of mitochondrial fission
E	0090149	biological_process	mitochondrial membrane fission
E	0099073	cellular_component	mitochondrion-derived vesicle
E	0160040	biological_process	mitocytosis
E	1900063	biological_process	regulation of peroxisome organization
E	1901524	biological_process	regulation of mitophagy
E	1903532	biological_process	positive regulation of secretion by cell
E	1903578	biological_process	regulation of ATP metabolic process
F	0005741	cellular_component	mitochondrial outer membrane
F	0007005	biological_process	mitochondrion organization
G	0000166	molecular_function	nucleotide binding
G	0000266	biological_process	mitochondrial fission
G	0003924	molecular_function	GTPase activity
G	0005096	molecular_function	GTPase activator activity
G	0005515	molecular_function	protein binding
G	0005525	molecular_function	GTP binding
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005741	cellular_component	mitochondrial outer membrane
G	0005777	cellular_component	peroxisome
G	0005783	cellular_component	endoplasmic reticulum
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0005794	cellular_component	Golgi apparatus
G	0005829	cellular_component	cytosol
G	0005874	cellular_component	microtubule
G	0005903	cellular_component	brush border
G	0005905	cellular_component	clathrin-coated pit
G	0006816	biological_process	calcium ion transport
G	0006897	biological_process	endocytosis
G	0007005	biological_process	mitochondrion organization
G	0007029	biological_process	endoplasmic reticulum organization
G	0008017	molecular_function	microtubule binding
G	0008289	molecular_function	lipid binding
G	0010468	biological_process	regulation of gene expression
G	0010821	biological_process	regulation of mitochondrion organization
G	0012501	biological_process	programmed cell death
G	0012505	cellular_component	endomembrane system
G	0016020	cellular_component	membrane
G	0016559	biological_process	peroxisome fission
G	0016787	molecular_function	hydrolase activity
G	0030672	cellular_component	synaptic vesicle membrane
G	0030742	molecular_function	GTP-dependent protein binding
G	0031267	molecular_function	small GTPase binding
G	0031410	cellular_component	cytoplasmic vesicle
G	0031625	molecular_function	ubiquitin protein ligase binding
G	0032991	cellular_component	protein-containing complex
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0043653	biological_process	mitochondrial fragmentation involved in apoptotic process
G	0048312	biological_process	intracellular distribution of mitochondria
G	0048471	cellular_component	perinuclear region of cytoplasm
G	0048511	biological_process	rhythmic process
G	0050714	biological_process	positive regulation of protein secretion
G	0051259	biological_process	protein complex oligomerization
G	0060047	biological_process	heart contraction
G	0070585	biological_process	protein localization to mitochondrion
G	0090023	biological_process	positive regulation of neutrophil chemotaxis
G	0090141	biological_process	positive regulation of mitochondrial fission
G	0090149	biological_process	mitochondrial membrane fission
G	0099073	cellular_component	mitochondrion-derived vesicle
G	0160040	biological_process	mitocytosis
G	1900063	biological_process	regulation of peroxisome organization
G	1901524	biological_process	regulation of mitophagy
G	1903532	biological_process	positive regulation of secretion by cell
G	1903578	biological_process	regulation of ATP metabolic process
H	0005741	cellular_component	mitochondrial outer membrane
H	0007005	biological_process	mitochondrion organization
I	0000166	molecular_function	nucleotide binding
I	0000266	biological_process	mitochondrial fission
I	0003924	molecular_function	GTPase activity
I	0005096	molecular_function	GTPase activator activity
I	0005515	molecular_function	protein binding
I	0005525	molecular_function	GTP binding
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005741	cellular_component	mitochondrial outer membrane
I	0005777	cellular_component	peroxisome
I	0005783	cellular_component	endoplasmic reticulum
I	0005789	cellular_component	endoplasmic reticulum membrane
I	0005794	cellular_component	Golgi apparatus
I	0005829	cellular_component	cytosol
I	0005874	cellular_component	microtubule
I	0005903	cellular_component	brush border
I	0005905	cellular_component	clathrin-coated pit
I	0006816	biological_process	calcium ion transport
I	0006897	biological_process	endocytosis
I	0007005	biological_process	mitochondrion organization
I	0007029	biological_process	endoplasmic reticulum organization
I	0008017	molecular_function	microtubule binding
I	0008289	molecular_function	lipid binding
I	0010468	biological_process	regulation of gene expression
I	0010821	biological_process	regulation of mitochondrion organization
I	0012501	biological_process	programmed cell death
I	0012505	cellular_component	endomembrane system
I	0016020	cellular_component	membrane
I	0016559	biological_process	peroxisome fission
I	0016787	molecular_function	hydrolase activity
I	0030672	cellular_component	synaptic vesicle membrane
I	0030742	molecular_function	GTP-dependent protein binding
I	0031267	molecular_function	small GTPase binding
I	0031410	cellular_component	cytoplasmic vesicle
I	0031625	molecular_function	ubiquitin protein ligase binding
I	0032991	cellular_component	protein-containing complex
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0043653	biological_process	mitochondrial fragmentation involved in apoptotic process
I	0048312	biological_process	intracellular distribution of mitochondria
I	0048471	cellular_component	perinuclear region of cytoplasm
I	0048511	biological_process	rhythmic process
I	0050714	biological_process	positive regulation of protein secretion
I	0051259	biological_process	protein complex oligomerization
I	0060047	biological_process	heart contraction
I	0070585	biological_process	protein localization to mitochondrion
I	0090023	biological_process	positive regulation of neutrophil chemotaxis
I	0090141	biological_process	positive regulation of mitochondrial fission
I	0090149	biological_process	mitochondrial membrane fission
I	0099073	cellular_component	mitochondrion-derived vesicle
I	0160040	biological_process	mitocytosis
I	1900063	biological_process	regulation of peroxisome organization
I	1901524	biological_process	regulation of mitophagy
I	1903532	biological_process	positive regulation of secretion by cell
I	1903578	biological_process	regulation of ATP metabolic process
J	0005741	cellular_component	mitochondrial outer membrane
J	0007005	biological_process	mitochondrion organization
K	0000166	molecular_function	nucleotide binding
K	0000266	biological_process	mitochondrial fission
K	0003924	molecular_function	GTPase activity
K	0005096	molecular_function	GTPase activator activity
K	0005515	molecular_function	protein binding
K	0005525	molecular_function	GTP binding
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005741	cellular_component	mitochondrial outer membrane
K	0005777	cellular_component	peroxisome
K	0005783	cellular_component	endoplasmic reticulum
K	0005789	cellular_component	endoplasmic reticulum membrane
K	0005794	cellular_component	Golgi apparatus
K	0005829	cellular_component	cytosol
K	0005874	cellular_component	microtubule
K	0005903	cellular_component	brush border
K	0005905	cellular_component	clathrin-coated pit
K	0006816	biological_process	calcium ion transport
K	0006897	biological_process	endocytosis
K	0007005	biological_process	mitochondrion organization
K	0007029	biological_process	endoplasmic reticulum organization
K	0008017	molecular_function	microtubule binding
K	0008289	molecular_function	lipid binding
K	0010468	biological_process	regulation of gene expression
K	0010821	biological_process	regulation of mitochondrion organization
K	0012501	biological_process	programmed cell death
K	0012505	cellular_component	endomembrane system
K	0016020	cellular_component	membrane
K	0016559	biological_process	peroxisome fission
K	0016787	molecular_function	hydrolase activity
K	0030672	cellular_component	synaptic vesicle membrane
K	0030742	molecular_function	GTP-dependent protein binding
K	0031267	molecular_function	small GTPase binding
K	0031410	cellular_component	cytoplasmic vesicle
K	0031625	molecular_function	ubiquitin protein ligase binding
K	0032991	cellular_component	protein-containing complex
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0043653	biological_process	mitochondrial fragmentation involved in apoptotic process
K	0048312	biological_process	intracellular distribution of mitochondria
K	0048471	cellular_component	perinuclear region of cytoplasm
K	0048511	biological_process	rhythmic process
K	0050714	biological_process	positive regulation of protein secretion
K	0051259	biological_process	protein complex oligomerization
K	0060047	biological_process	heart contraction
K	0070585	biological_process	protein localization to mitochondrion
K	0090023	biological_process	positive regulation of neutrophil chemotaxis
K	0090141	biological_process	positive regulation of mitochondrial fission
K	0090149	biological_process	mitochondrial membrane fission
K	0099073	cellular_component	mitochondrion-derived vesicle
K	0160040	biological_process	mitocytosis
K	1900063	biological_process	regulation of peroxisome organization
K	1901524	biological_process	regulation of mitophagy
K	1903532	biological_process	positive regulation of secretion by cell
K	1903578	biological_process	regulation of ATP metabolic process
L	0005741	cellular_component	mitochondrial outer membrane
L	0007005	biological_process	mitochondrion organization
M	0000166	molecular_function	nucleotide binding
M	0000266	biological_process	mitochondrial fission
M	0003924	molecular_function	GTPase activity
M	0005096	molecular_function	GTPase activator activity
M	0005515	molecular_function	protein binding
M	0005525	molecular_function	GTP binding
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005741	cellular_component	mitochondrial outer membrane
M	0005777	cellular_component	peroxisome
M	0005783	cellular_component	endoplasmic reticulum
M	0005789	cellular_component	endoplasmic reticulum membrane
M	0005794	cellular_component	Golgi apparatus
M	0005829	cellular_component	cytosol
M	0005874	cellular_component	microtubule
M	0005903	cellular_component	brush border
M	0005905	cellular_component	clathrin-coated pit
M	0006816	biological_process	calcium ion transport
M	0006897	biological_process	endocytosis
M	0007005	biological_process	mitochondrion organization
M	0007029	biological_process	endoplasmic reticulum organization
M	0008017	molecular_function	microtubule binding
M	0008289	molecular_function	lipid binding
M	0010468	biological_process	regulation of gene expression
M	0010821	biological_process	regulation of mitochondrion organization
M	0012501	biological_process	programmed cell death
M	0012505	cellular_component	endomembrane system
M	0016020	cellular_component	membrane
M	0016559	biological_process	peroxisome fission
M	0016787	molecular_function	hydrolase activity
M	0030672	cellular_component	synaptic vesicle membrane
M	0030742	molecular_function	GTP-dependent protein binding
M	0031267	molecular_function	small GTPase binding
M	0031410	cellular_component	cytoplasmic vesicle
M	0031625	molecular_function	ubiquitin protein ligase binding
M	0032991	cellular_component	protein-containing complex
M	0042802	molecular_function	identical protein binding
M	0042803	molecular_function	protein homodimerization activity
M	0043653	biological_process	mitochondrial fragmentation involved in apoptotic process
M	0048312	biological_process	intracellular distribution of mitochondria
M	0048471	cellular_component	perinuclear region of cytoplasm
M	0048511	biological_process	rhythmic process
M	0050714	biological_process	positive regulation of protein secretion
M	0051259	biological_process	protein complex oligomerization
M	0060047	biological_process	heart contraction
M	0070585	biological_process	protein localization to mitochondrion
M	0090023	biological_process	positive regulation of neutrophil chemotaxis
M	0090141	biological_process	positive regulation of mitochondrial fission
M	0090149	biological_process	mitochondrial membrane fission
M	0099073	cellular_component	mitochondrion-derived vesicle
M	0160040	biological_process	mitocytosis
M	1900063	biological_process	regulation of peroxisome organization
M	1901524	biological_process	regulation of mitophagy
M	1903532	biological_process	positive regulation of secretion by cell
M	1903578	biological_process	regulation of ATP metabolic process
N	0005741	cellular_component	mitochondrial outer membrane
N	0007005	biological_process	mitochondrion organization
O	0000166	molecular_function	nucleotide binding
O	0000266	biological_process	mitochondrial fission
O	0003924	molecular_function	GTPase activity
O	0005096	molecular_function	GTPase activator activity
O	0005515	molecular_function	protein binding
O	0005525	molecular_function	GTP binding
O	0005737	cellular_component	cytoplasm
O	0005739	cellular_component	mitochondrion
O	0005741	cellular_component	mitochondrial outer membrane
O	0005777	cellular_component	peroxisome
O	0005783	cellular_component	endoplasmic reticulum
O	0005789	cellular_component	endoplasmic reticulum membrane
O	0005794	cellular_component	Golgi apparatus
O	0005829	cellular_component	cytosol
O	0005874	cellular_component	microtubule
O	0005903	cellular_component	brush border
O	0005905	cellular_component	clathrin-coated pit
O	0006816	biological_process	calcium ion transport
O	0006897	biological_process	endocytosis
O	0007005	biological_process	mitochondrion organization
O	0007029	biological_process	endoplasmic reticulum organization
O	0008017	molecular_function	microtubule binding
O	0008289	molecular_function	lipid binding
O	0010468	biological_process	regulation of gene expression
O	0010821	biological_process	regulation of mitochondrion organization
O	0012501	biological_process	programmed cell death
O	0012505	cellular_component	endomembrane system
O	0016020	cellular_component	membrane
O	0016559	biological_process	peroxisome fission
O	0016787	molecular_function	hydrolase activity
O	0030672	cellular_component	synaptic vesicle membrane
O	0030742	molecular_function	GTP-dependent protein binding
O	0031267	molecular_function	small GTPase binding
O	0031410	cellular_component	cytoplasmic vesicle
O	0031625	molecular_function	ubiquitin protein ligase binding
O	0032991	cellular_component	protein-containing complex
O	0042802	molecular_function	identical protein binding
O	0042803	molecular_function	protein homodimerization activity
O	0043653	biological_process	mitochondrial fragmentation involved in apoptotic process
O	0048312	biological_process	intracellular distribution of mitochondria
O	0048471	cellular_component	perinuclear region of cytoplasm
O	0048511	biological_process	rhythmic process
O	0050714	biological_process	positive regulation of protein secretion
O	0051259	biological_process	protein complex oligomerization
O	0060047	biological_process	heart contraction
O	0070585	biological_process	protein localization to mitochondrion
O	0090023	biological_process	positive regulation of neutrophil chemotaxis
O	0090141	biological_process	positive regulation of mitochondrial fission
O	0090149	biological_process	mitochondrial membrane fission
O	0099073	cellular_component	mitochondrion-derived vesicle
O	0160040	biological_process	mitocytosis
O	1900063	biological_process	regulation of peroxisome organization
O	1901524	biological_process	regulation of mitophagy
O	1903532	biological_process	positive regulation of secretion by cell
O	1903578	biological_process	regulation of ATP metabolic process
P	0005741	cellular_component	mitochondrial outer membrane
P	0007005	biological_process	mitochondrion organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	binding site for residue GCP A 801

Chain	Residue
A	GLN34
A	THR55
A	VAL58
A	THR59
A	GLY149
A	LYS216
A	ASP218
A	LEU219
A	VAL245
A	ASN246
A	ARG247
A	SER35
A	SER248
A	GLN249
A	ILE252
A	MG802
A	SER36
A	GLY37
A	LYS38
A	SER39
A	SER40
A	ARG53
A	GLY54

---

site_id	AC2
Number of Residues	3
Details	binding site for residue MG A 802

Chain	Residue
A	SER39
A	THR59
A	GCP801

---

site_id	AC3
Number of Residues	23
Details	binding site for residue GCP C 801

Chain	Residue
C	GLN34
C	SER35
C	SER36
C	GLY37
C	LYS38
C	SER39
C	SER40
C	ARG53
C	GLY54
C	THR55
C	VAL58
C	THR59
C	GLY149
C	LYS216
C	ASP218
C	LEU219
C	VAL245
C	ASN246
C	ARG247
C	SER248
C	GLN249
C	ILE252
C	MG802

---

site_id	AC4
Number of Residues	3
Details	binding site for residue MG C 802

Chain	Residue
C	SER39
C	THR59
C	GCP801

---

site_id	AC5
Number of Residues	23
Details	binding site for residue GCP E 801

Chain	Residue
E	GLN34
E	SER35
E	SER36
E	GLY37
E	LYS38
E	SER39
E	SER40
E	ARG53
E	GLY54
E	THR55
E	VAL58
E	THR59
E	GLY149
E	LYS216
E	ASP218
E	LEU219
E	VAL245
E	ASN246
E	ARG247
E	SER248
E	GLN249
E	ILE252
E	MG802

---

site_id	AC6
Number of Residues	3
Details	binding site for residue MG E 802

Chain	Residue
E	SER39
E	THR59
E	GCP801

---

site_id	AC7
Number of Residues	23
Details	binding site for residue GCP G 801

Chain	Residue
G	ILE252
G	MG802
G	GLN34
G	SER35
G	SER36
G	GLY37
G	LYS38
G	SER39
G	SER40
G	ARG53
G	GLY54
G	THR55
G	VAL58
G	THR59
G	GLY149
G	LYS216
G	ASP218
G	LEU219
G	VAL245
G	ASN246
G	ARG247
G	SER248
G	GLN249

---

site_id	AC8
Number of Residues	3
Details	binding site for residue MG G 802

Chain	Residue
G	SER39
G	THR59
G	GCP801

---

site_id	AC9
Number of Residues	23
Details	binding site for residue GCP I 801

Chain	Residue
I	GLN34
I	SER35
I	SER36
I	GLY37
I	LYS38
I	SER39
I	SER40
I	ARG53
I	GLY54
I	THR55
I	VAL58
I	THR59
I	GLY149
I	LYS216
I	ASP218
I	LEU219
I	VAL245
I	ASN246
I	ARG247
I	SER248
I	GLN249
I	ILE252
I	MG802

---

site_id	AD1
Number of Residues	3
Details	binding site for residue MG I 802

Chain	Residue
I	SER39
I	THR59
I	GCP801

---

site_id	AD2
Number of Residues	23
Details	binding site for residue GCP K 801

Chain	Residue
K	GLN34
K	SER35
K	SER36
K	GLY37
K	LYS38
K	SER39
K	SER40
K	ARG53
K	GLY54
K	THR55
K	VAL58
K	THR59
K	GLY149
K	LYS216
K	ASP218
K	LEU219
K	VAL245
K	ASN246
K	ARG247
K	SER248
K	GLN249
K	ILE252
K	MG802

---

site_id	AD3
Number of Residues	3
Details	binding site for residue MG K 802

Chain	Residue
K	SER39
K	THR59
K	GCP801

---

site_id	AD4
Number of Residues	23
Details	binding site for residue GCP M 801

Chain	Residue
M	GLN34
M	SER35
M	SER36
M	GLY37
M	LYS38
M	SER39
M	SER40
M	ARG53
M	GLY54
M	THR55
M	VAL58
M	THR59
M	GLY149
M	LYS216
M	ASP218
M	LEU219
M	VAL245
M	ASN246
M	ARG247
M	SER248
M	GLN249
M	ILE252
M	MG802

---

site_id	AD5
Number of Residues	3
Details	binding site for residue MG M 802

Chain	Residue
M	SER39
M	THR59
M	GCP801

---

site_id	AD6
Number of Residues	23
Details	binding site for residue GCP O 801

Chain	Residue
O	GLN34
O	SER35
O	SER36
O	GLY37
O	LYS38
O	SER39
O	SER40
O	ARG53
O	GLY54
O	THR55
O	VAL58
O	THR59
O	GLY149
O	LYS216
O	ASP218
O	LEU219
O	VAL245
O	ASN246
O	ARG247
O	SER248
O	GLN249
O	ILE252
O	MG802

---

site_id	AD7
Number of Residues	3
Details	binding site for residue MG O 802

Chain	Residue
O	SER39
O	THR59
O	GCP801

---

Functional Information from PROSITE/UniProt

site_id	PS00410
Number of Residues	10
Details	G_DYNAMIN_1 Dynamin-type guanine nucleotide-binding (G) domain signature. LPRGTGIVTR

Chain	Residue	Details
A	LEU51-ARG60

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	728
Details	Domain: {"description":"GED","evidences":[{"source":"PROSITE-ProRule","id":"PRU00720","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	56
Details	Region: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Region: {"description":"G2 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Region: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	24
Details	Region: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Region: {"description":"G5 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1160
Details	Region: {"description":"Middle domain","evidences":[{"source":"PubMed","id":"15208300","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	112
Details	Region: {"description":"Important for homodimerization","evidences":[{"source":"PubMed","id":"23584531","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	136
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23977156","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	8
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine; by CAMK1 and PKA","evidences":[{"source":"PubMed","id":"17553808","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18695047","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18838687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23283981","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26122121","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32439975","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"PubMed","id":"19342591","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---