5WJC
Crystal structure of Schizosaccharomyces pombe Mis16 in complex with Eic1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000510 | molecular_function | H3-H4 histone complex chaperone activity |
| A | 0000775 | cellular_component | chromosome, centromeric region |
| A | 0000776 | cellular_component | kinetochore |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006325 | biological_process | chromatin organization |
| A | 0006338 | biological_process | chromatin remodeling |
| A | 0034080 | biological_process | CENP-A containing chromatin assembly |
| A | 0042393 | molecular_function | histone binding |
| A | 0098654 | cellular_component | CENP-A recruiting complex |
| A | 0140462 | biological_process | pericentric heterochromatin organization |
| A | 0140463 | molecular_function | chromatin-protein adaptor activity |
| B | 0000775 | cellular_component | chromosome, centromeric region |
| B | 0000776 | cellular_component | kinetochore |
| B | 0005515 | molecular_function | protein binding |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0034080 | biological_process | CENP-A containing chromatin assembly |
| B | 0034506 | cellular_component | chromosome, centromeric core domain |
| B | 0051301 | biological_process | cell division |
| B | 0051315 | biological_process | attachment of mitotic spindle microtubules to kinetochore |
| B | 0098654 | cellular_component | CENP-A recruiting complex |
| B | 0140462 | biological_process | pericentric heterochromatin organization |
| B | 0140463 | molecular_function | chromatin-protein adaptor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LATGaeDqVICLWDV |
| Chain | Residue | Details |
| A | LEU198-VAL212 | |
| A | LEU297-LEU311 | |
| A | LEU341-LEU355 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Region: {"description":"Interaction with the histone H4 N-terminus","evidences":[{"source":"UniProtKB","id":"P39984","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for interaction with HAT1","evidences":[{"source":"UniProtKB","id":"P39984","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
