5WE2

Structural Basis for Telomere Length Regulation by the Shelterin Bridge

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000723	biological_process	telomere maintenance
A	0000781	cellular_component	chromosome, telomeric region
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0010833	biological_process	telomere maintenance via telomere lengthening
A	0016233	biological_process	telomere capping
A	0032200	biological_process	telomere organization
A	0032206	biological_process	positive regulation of telomere maintenance
A	0070187	cellular_component	shelterin complex
A	0140445	cellular_component	chromosome, telomeric repeat region
C	0000723	biological_process	telomere maintenance
C	0000781	cellular_component	chromosome, telomeric region
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0010833	biological_process	telomere maintenance via telomere lengthening
C	0016233	biological_process	telomere capping
C	0032200	biological_process	telomere organization
C	0032206	biological_process	positive regulation of telomere maintenance
C	0070187	cellular_component	shelterin complex
C	0140445	cellular_component	chromosome, telomeric repeat region

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN B 601

Chain	Residue
A	HIS49
B	CYS479
B	CYS482
B	HIS488

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN D 601

Chain	Residue
C	HIS49
D	CYS479
D	CYS482
D	HIS488

---