5W9G

Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 9k (SRI-30023)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MN A 201

Chain	Residue
A	HIS41
A	ASP108
A	GLU119
A	ILE120
A	KU2204

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site_id	AC2
Number of Residues	5
Details	binding site for residue MN A 202

Chain	Residue
A	HOH303
A	GLU80
A	ASP108
A	KU2204
A	HOH302

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site_id	AC3
Number of Residues	1
Details	binding site for residue CL A 203

Chain	Residue
A	ARG75

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site_id	AC4
Number of Residues	12
Details	binding site for residue KU2 A 204

Chain	Residue
A	TYR24
A	ILE38
A	HIS41
A	GLU80
A	ASP108
A	GLU119
A	ILE120
A	TYR130
A	MN201
A	MN202
A	HOH302
A	HOH306

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site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 A 205

Chain	Residue
A	GLU31
A	THR32
A	ASN33
A	LYS34
A	SER194

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