5W6M
Crystal structure of the human histidyl-tRNA synthetase mutant D175E
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004821 | molecular_function | histidine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| B | 0004821 | molecular_function | histidine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006427 | biological_process | histidyl-tRNA aminoacylation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25151410, ECO:0007744|PDB:4PHC |
| Chain | Residue | Details |
| A | ASP130 | |
| B | ASP177 | |
| B | ARG326 | |
| B | TYR330 | |
| A | ARG157 | |
| A | GLN173 | |
| A | ASP177 | |
| A | ARG326 | |
| A | TYR330 | |
| B | ASP130 | |
| B | ARG157 | |
| B | GLN173 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q99KK9 |
| Chain | Residue | Details |
| A | SER66 | |
| B | SER66 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER356 | |
| B | SER356 |
