Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5W5R

Agrobacterium tumefaciens ADP-glucose pyrophosphorylase P96A mutant bound to activator pyruvate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005978	biological_process	glycogen biosynthetic process
A	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
A	0009058	biological_process	biosynthetic process
B	0005978	biological_process	glycogen biosynthetic process
B	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
B	0009058	biological_process	biosynthetic process
C	0005978	biological_process	glycogen biosynthetic process
C	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
C	0009058	biological_process	biosynthetic process
D	0005978	biological_process	glycogen biosynthetic process
D	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
D	0009058	biological_process	biosynthetic process
E	0005978	biological_process	glycogen biosynthetic process
E	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
E	0009058	biological_process	biosynthetic process
F	0005978	biological_process	glycogen biosynthetic process
F	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
F	0009058	biological_process	biosynthetic process
G	0005978	biological_process	glycogen biosynthetic process
G	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
G	0009058	biological_process	biosynthetic process
H	0005978	biological_process	glycogen biosynthetic process
H	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
H	0009058	biological_process	biosynthetic process
I	0005978	biological_process	glycogen biosynthetic process
I	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
I	0009058	biological_process	biosynthetic process
J	0005978	biological_process	glycogen biosynthetic process
J	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
J	0009058	biological_process	biosynthetic process
K	0005978	biological_process	glycogen biosynthetic process
K	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
K	0009058	biological_process	biosynthetic process
L	0005978	biological_process	glycogen biosynthetic process
L	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
L	0009058	biological_process	biosynthetic process
M	0005978	biological_process	glycogen biosynthetic process
M	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
M	0009058	biological_process	biosynthetic process
N	0005978	biological_process	glycogen biosynthetic process
N	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
N	0009058	biological_process	biosynthetic process
O	0005978	biological_process	glycogen biosynthetic process
O	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
O	0009058	biological_process	biosynthetic process
P	0005978	biological_process	glycogen biosynthetic process
P	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
P	0009058	biological_process	biosynthetic process
Q	0005978	biological_process	glycogen biosynthetic process
Q	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
Q	0009058	biological_process	biosynthetic process
R	0005978	biological_process	glycogen biosynthetic process
R	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
R	0009058	biological_process	biosynthetic process
T	0005978	biological_process	glycogen biosynthetic process
T	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
T	0009058	biological_process	biosynthetic process
U	0005978	biological_process	glycogen biosynthetic process
U	0008878	molecular_function	glucose-1-phosphate adenylyltransferase activity
U	0009058	biological_process	biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue SO4 A 501

Chain	Residue
A	SER335
A	ASN351
A	SER352
A	ARG369
A	HOH619
A	HOH814
A	HOH858

site_id	AC2
Number of Residues	6
Details	binding site for residue SO4 A 502

Chain	Residue
A	ARG46
A	SER73
A	HOH664
A	HOH697
A	ARG34
A	TYR40

site_id	AC3
Number of Residues	10
Details	binding site for residue PYR A 503

Chain	Residue
A	LYS44
A	THR307
A	PRO309
A	VAL328
A	SER329
A	GLY330
P	LYS44
P	PRO309
P	SER329
P	GLY330

site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 B 501

Chain	Residue
B	ARG319
B	SER335
B	ASN351
B	SER352
B	ARG369
B	HOH790
B	HOH834

site_id	AC5
Number of Residues	7
Details	binding site for residue SO4 B 502

Chain	Residue
B	ARG34
B	TYR40
B	ARG46
B	SER73
B	ARG76
B	HIS380
B	HOH722

site_id	AC6
Number of Residues	6
Details	binding site for residue SO4 C 501

Chain	Residue
C	SER335
C	ASN351
C	SER352
C	ARG369
C	HOH704
C	HOH854

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 C 502

Chain	Residue
C	ARG34
C	TYR40
C	ARG46
C	SER73
C	HOH646

site_id	AC8
Number of Residues	7
Details	binding site for residue SO4 D 501

Chain	Residue
D	SER335
D	ASN351
D	SER352
D	ARG369
D	HOH669
D	HOH791
D	HOH821

site_id	AC9
Number of Residues	6
Details	binding site for residue SO4 D 502

Chain	Residue
D	ARG34
D	TYR40
D	ARG46
D	SER73
D	HOH622
D	HOH714

site_id	AD1
Number of Residues	10
Details	binding site for residue PYR D 503

Chain	Residue
D	LYS44
D	PRO308
D	SER329
D	GLY330
D	HOH636
M	LYS44
M	PRO309
M	VAL328
M	SER329
M	GLY330

site_id	AD2
Number of Residues	6
Details	binding site for residue SO4 E 501

Chain	Residue
E	SER335
E	ASN351
E	SER352
E	ARG369
E	HOH817
E	HOH826

site_id	AD3
Number of Residues	5
Details	binding site for residue SO4 E 502

Chain	Residue
E	ARG34
E	TYR40
E	ARG46
E	SER73
E	HOH647

site_id	AD4
Number of Residues	3
Details	binding site for residue SO4 E 503

Chain	Residue
E	ASP286
E	VAL287
E	HOH722

site_id	AD5
Number of Residues	13
Details	binding site for residue PYR E 504

Chain	Residue
E	LYS44
E	PRO308
E	PRO309
E	ALA310
E	VAL328
E	SER329
E	GLY330
O	LYS44
O	PRO309
O	ALA310
O	VAL328
O	SER329
O	GLY330

site_id	AD6
Number of Residues	4
Details	binding site for residue SO4 H 501

Chain	Residue
H	ASN351
H	SER352
H	ARG369
H	SER335

site_id	AD7
Number of Residues	5
Details	binding site for residue SO4 H 502

Chain	Residue
H	ARG34
H	TYR40
H	ARG46
H	SER73
H	HOH631

site_id	AD8
Number of Residues	10
Details	binding site for residue PYR H 503

Chain	Residue
G	LYS44
G	PRO309
G	GLY330
H	LYS44
H	PRO308
H	PRO309
H	VAL328
H	SER329
H	GLY330
H	HOH776

site_id	AD9
Number of Residues	7
Details	binding site for residue SO4 I 501

Chain	Residue
I	SER335
I	ASN351
I	SER352
I	ARG369
I	HOH673
I	HOH746
I	HOH769

site_id	AE1
Number of Residues	6
Details	binding site for residue SO4 I 502

Chain	Residue
I	ARG34
I	TYR40
I	ARG46
I	SER73
I	HOH625
I	HOH706

site_id	AE2
Number of Residues	12
Details	binding site for residue PYR I 503

Chain	Residue
C	LYS44
C	PRO309
C	ALA310
C	VAL328
C	SER329
C	GLY330
I	LYS44
I	PRO309
I	ALA310
I	VAL328
I	SER329
I	GLY330

site_id	AE3
Number of Residues	9
Details	binding site for residue SO4 J 501

Chain	Residue
J	SER335
J	ASN351
J	SER352
J	ARG369
J	HOH704
J	HOH747
J	HOH758
J	HOH872
J	HOH877

site_id	AE4
Number of Residues	10
Details	binding site for residue SO4 J 502

Chain	Residue
J	ARG34
J	TYR40
J	ARG46
J	SER73
J	ARG76
J	HIS380
J	HOH618
J	HOH755
J	HOH784
J	HOH796

site_id	AE5
Number of Residues	13
Details	binding site for residue PYR J 503

Chain	Residue
J	LYS44
J	PRO309
J	ALA310
J	SER329
J	GLY330
J	HOH608
J	HOH623
R	LYS44
R	PRO308
R	PRO309
R	VAL328
R	SER329
R	GLY330

site_id	AE6
Number of Residues	6
Details	binding site for residue SO4 K 501

Chain	Residue
K	SER335
K	ASN351
K	SER352
K	ARG369
K	HOH629
K	HOH853

site_id	AE7
Number of Residues	7
Details	binding site for residue SO4 K 502

Chain	Residue
K	ARG34
K	TYR40
K	ARG46
K	SER73
K	ARG76
K	HOH606
K	HOH709

site_id	AE8
Number of Residues	12
Details	binding site for residue PYR K 503

Chain	Residue
B	PRO309
B	ALA310
B	VAL328
B	SER329
B	GLY330
K	LYS44
K	PRO309
K	ALA310
K	VAL328
K	SER329
K	GLY330
K	HOH632

site_id	AE9
Number of Residues	5
Details	binding site for residue SO4 L 501

Chain	Residue
L	ARG34
L	TYR40
L	ARG46
L	SER73
L	HOH618

site_id	AF1
Number of Residues	7
Details	binding site for residue SO4 L 502

Chain	Residue
L	HIS314
L	ARG319
L	SER335
L	ASN351
L	SER352
L	ARG369
L	HOH726

site_id	AF2
Number of Residues	6
Details	binding site for residue SO4 N 501

Chain	Residue
N	ARG34
N	TYR40
N	ARG46
N	SER73
N	HIS380
N	HOH788

site_id	AF3
Number of Residues	6
Details	binding site for residue SO4 N 502

Chain	Residue
N	ARG319
N	SER335
N	ASN351
N	SER352
N	ARG369
N	HOH689

site_id	AF4
Number of Residues	6
Details	binding site for residue SO4 O 501

Chain	Residue
O	SER335
O	ASN351
O	SER352
O	ARG369
O	HOH661
O	HOH735

site_id	AF5
Number of Residues	6
Details	binding site for residue SO4 O 502

Chain	Residue
O	ARG34
O	TYR40
O	ARG46
O	SER73
O	HOH623
O	HOH759

site_id	AF6
Number of Residues	6
Details	binding site for residue SO4 P 501

Chain	Residue
P	SER335
P	ASN351
P	SER352
P	ARG369
P	HOH608
P	HOH686

site_id	AF7
Number of Residues	7
Details	binding site for residue SO4 P 502

Chain	Residue
P	ARG34
P	TYR40
P	ARG46
P	SER73
P	ARG76
P	HIS380
P	HOH711

site_id	AF8
Number of Residues	5
Details	binding site for residue SO4 Q 501

Chain	Residue
Q	SER335
Q	ASN351
Q	SER352
Q	ARG369
Q	HOH685

site_id	AF9
Number of Residues	5
Details	binding site for residue SO4 Q 502

Chain	Residue
Q	ARG34
Q	TYR40
Q	ARG46
Q	SER73
Q	HOH625

site_id	AG1
Number of Residues	7
Details	binding site for residue SO4 R 501

Chain	Residue
R	SER335
R	ASN351
R	SER352
R	ARG369
R	HOH756
R	HOH869
R	HOH892

site_id	AG2
Number of Residues	8
Details	binding site for residue SO4 R 502

Chain	Residue
R	ARG34
R	TYR40
R	ARG46
R	SER73
R	ARG76
R	HIS380
R	HOH682
R	HOH784

site_id	AG3
Number of Residues	6
Details	binding site for residue SO4 F 501

Chain	Residue
F	SER335
F	ASN351
F	SER352
F	ARG369
F	HOH654
F	HOH752

site_id	AG4
Number of Residues	8
Details	binding site for residue SO4 F 502

Chain	Residue
F	ARG34
F	TYR40
F	ARG46
F	SER73
F	HOH644
F	HOH663
F	HOH768
F	HOH845

site_id	AG5
Number of Residues	13
Details	binding site for residue PYR F 503

Chain	Residue
F	PRO308
F	PRO309
F	VAL328
F	SER329
F	GLY330
F	HOH618
F	HOH775
Q	LYS44
Q	PRO309
Q	ALA310
Q	SER329
Q	GLY330
Q	HOH726

site_id	AG6
Number of Residues	7
Details	binding site for residue SO4 G 501

Chain	Residue
G	ARG34
G	TYR40
G	ARG46
G	SER73
G	ARG76
G	HIS380
G	HOH703

site_id	AG7
Number of Residues	7
Details	binding site for residue SO4 G 502

Chain	Residue
G	SER335
G	ASN351
G	SER352
G	ARG369
G	HOH622
G	HOH633
G	HOH692

site_id	AG8
Number of Residues	7
Details	binding site for residue SO4 M 501

Chain	Residue
M	SER335
M	ASN351
M	SER352
M	ARG369
M	HOH655
M	HOH772
M	HOH856

site_id	AG9
Number of Residues	7
Details	binding site for residue SO4 M 502

Chain	Residue
M	ARG34
M	TYR40
M	ARG46
M	SER73
M	ARG76
M	HIS380
M	HOH757

site_id	AH1
Number of Residues	7
Details	binding site for residue SO4 T 501

Chain	Residue
T	ARG34
T	TYR40
T	ARG46
T	SER73
T	HOH615
T	HOH636
T	HOH838

site_id	AH2
Number of Residues	7
Details	binding site for residue SO4 T 502

Chain	Residue
T	ARG319
T	SER335
T	ASN351
T	SER352
T	ARG369
T	HOH799
T	HOH856

site_id	AH3
Number of Residues	4
Details	binding site for residue SO4 T 503

Chain	Residue
T	ARG269
T	ASP270
T	VAL271
T	ALA276

site_id	AH4
Number of Residues	5
Details	binding site for residue SO4 U 501

Chain	Residue
U	SER335
U	ASN351
U	SER352
U	ARG369
U	HOH654

site_id	AH5
Number of Residues	7
Details	binding site for residue SO4 U 502

Chain	Residue
U	ARG34
U	TYR40
U	ARG46
U	SER73
U	HIS380
U	HOH643
U	HOH685

site_id	AH6
Number of Residues	12
Details	binding site for residue PYR U 503

Chain	Residue
T	LYS44
T	PRO309
T	ALA310
T	VAL328
T	SER329
T	GLY330
U	LYS44
U	PRO309
U	ALA310
U	VAL328
U	SER329
U	GLY330

Functional Information from PROSITE/UniProt

site_id	PS00808
Number of Residues	20
Details	ADP_GLC_PYROPHOSPH_1 ADP-glucose pyrophosphorylase signature 1. AGGrGSrLkeLTdrrAkPAV

Chain	Residue	Details
A	ALA20-VAL39

site_id	PS00809
Number of Residues	9
Details	ADP_GLC_PYROPHOSPH_2 ADP-glucose pyrophosphorylase signature 2. WYeGTADAV

Chain	Residue	Details
A	TRP107-VAL115

site_id	PS00810
Number of Residues	11
Details	ADP_GLC_PYROPHOSPH_3 ADP-glucose pyrophosphorylase signature 3. ASMGIYVFhtK

Chain	Residue	Details
A	ALA205-LYS215

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00624","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)