5W5D

Crystal structure of the primed SNARE-Complexin-Synaptotagmin-1 C2B complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
B	0005484	molecular_function	SNAP receptor activity
B	0006886	biological_process	intracellular protein transport
B	0016020	cellular_component	membrane
B	0016192	biological_process	vesicle-mediated transport
C	0000149	molecular_function	SNARE binding
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0017075	molecular_function	syntaxin-1 binding
E	0006836	biological_process	neurotransmitter transport
E	0019905	molecular_function	syntaxin binding
F	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MG C 101

Chain	Residue
C	ASP58
C	HOH204
C	HOH207
C	HOH208
D	HOH306
D	HOH311
D	HOH312

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Functional Information from PROSITE/UniProt

site_id	PS00914
Number of Residues	40
Details	SYNTAXIN Syntaxin / epimorphin family signature. RhseIikLEnsIrELhdMFmdMamlVesQGemIDrIEyn.V

Chain	Residue	Details
B	ARG198-VAL237

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00041

Chain	Residue	Details
F	ASP303
F	ASP309
F	ASP363
F	ASP365
F	ASP371

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903

Chain	Residue	Details
F	SER342
F	SER344
B	LYS253
B	LYS256

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P60879

Chain	Residue	Details
D	SER154

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKC => ECO:0000269|PubMed:12459461

Chain	Residue	Details
D	SER187

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