Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019430 | biological_process | removal of superoxide radicals |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 41 |
| Details | binding site for residue FAD A 401 |
| Chain | Residue |
| A | ILE36 |
| A | ALA64 |
| A | PHE67 |
| A | ALA68 |
| A | GLY71 |
| A | GLN72 |
| A | LEU73 |
| A | THR76 |
| A | ASN81 |
| A | GLU112 |
| A | THR113 |
| A | GLY37 |
| A | VAL114 |
| A | THR147 |
| A | GLY148 |
| A | ALA149 |
| A | CYS173 |
| A | LEU284 |
| A | GLY315 |
| A | ASP316 |
| A | ARG323 |
| A | GLN324 |
| A | SER38 |
| A | ALA325 |
| A | SER328 |
| A | PEG403 |
| A | HOH506 |
| A | HOH509 |
| A | HOH517 |
| A | HOH524 |
| A | HOH528 |
| A | HOH535 |
| A | HOH543 |
| A | GLY39 |
| A | HOH576 |
| B | TYR48 |
| A | PRO40 |
| A | GLY41 |
| A | TYR59 |
| A | GLU60 |
| A | GLY61 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | THR327 |
| A | SER331 |
| A | HOH557 |
| A | HOH606 |
| B | THR327 |
| B | GLY330 |
| B | ILE334 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 403 |
| Chain | Residue |
| A | THR75 |
| A | GLN164 |
| A | SER168 |
| A | ALA169 |
| A | ASP174 |
| A | FAD401 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 404 |
| Chain | Residue |
| A | GLU112 |
| A | GLU129 |
| A | GLU131 |
| A | HOH632 |
| A | HOH640 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 405 |
| Chain | Residue |
| A | THR242 |
| A | HOH594 |
| site_id | AC6 |
| Number of Residues | 43 |
| Details | binding site for residue FAD B 401 |
| Chain | Residue |
| B | HOH525 |
| B | HOH527 |
| B | HOH548 |
| B | HOH549 |
| B | HOH566 |
| A | TYR48 |
| A | TYR365 |
| B | ILE36 |
| B | GLY37 |
| B | SER38 |
| B | GLY39 |
| B | PRO40 |
| B | GLY41 |
| B | TYR59 |
| B | GLU60 |
| B | GLY61 |
| B | ALA64 |
| B | ASN65 |
| B | PHE67 |
| B | ALA68 |
| B | GLY71 |
| B | GLN72 |
| B | LEU73 |
| B | THR75 |
| B | THR76 |
| B | ASN81 |
| B | GLU112 |
| B | THR113 |
| B | VAL114 |
| B | THR147 |
| B | GLY148 |
| B | ALA149 |
| B | CYS173 |
| B | LEU284 |
| B | GLY315 |
| B | ASP316 |
| B | ARG323 |
| B | GLN324 |
| B | ALA325 |
| B | SER328 |
| B | HOH507 |
| B | HOH512 |
| B | HOH515 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| A | GLU263 |
| B | ASP96 |
| B | ARG99 |
| B | ALA100 |
| B | GLU103 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 403 |
| Chain | Residue |
| A | GLY130 |
| B | GLU263 |
| B | HOH588 |
| B | HOH616 |
| B | HOH623 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 404 |
| Chain | Residue |
| B | GLU112 |
| B | GLU129 |
| B | GLU131 |
| B | HOH597 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 23 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CavCDGavpiFrqkpLaVIGGGD |
| Chain | Residue | Details |
| A | CYS170-ASP192 | |
