5W3U

Crystal structure of SsoPox AsB5 mutant (V27A-I76T-Y97W-Y99F-L130P-L226V)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004063	molecular_function	aryldialkylphosphatase activity
A	0008270	molecular_function	zinc ion binding
A	0009056	biological_process	catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0046872	molecular_function	metal ion binding
B	0004063	molecular_function	aryldialkylphosphatase activity
B	0008270	molecular_function	zinc ion binding
B	0009056	biological_process	catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0046872	molecular_function	metal ion binding
C	0004063	molecular_function	aryldialkylphosphatase activity
C	0008270	molecular_function	zinc ion binding
C	0009056	biological_process	catabolic process
C	0016787	molecular_function	hydrolase activity
C	0016788	molecular_function	hydrolase activity, acting on ester bonds
C	0046872	molecular_function	metal ion binding
D	0004063	molecular_function	aryldialkylphosphatase activity
D	0008270	molecular_function	zinc ion binding
D	0009056	biological_process	catabolic process
D	0016787	molecular_function	hydrolase activity
D	0016788	molecular_function	hydrolase activity, acting on ester bonds
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue FE2 A 401

Chain	Residue
A	HIS22
A	HIS24
A	KCX137
A	ASP256
A	CO402
A	HOH506

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CO A 402

Chain	Residue
A	FE2401
A	HOH506
A	KCX137
A	HIS170
A	HIS199

---

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL A 403

Chain	Residue
A	PHE59
A	PHE284
A	ILE288
A	LYS292
C	GLN58

---

site_id	AC4
Number of Residues	5
Details	binding site for residue GOL A 404

Chain	Residue
A	ASN160
A	LYS164
A	GLY189
A	ASP191
A	LYS194

---

site_id	AC5
Number of Residues	6
Details	binding site for residue FE2 B 401

Chain	Residue
B	HIS22
B	HIS24
B	KCX137
B	ASP256
B	CO402
B	HOH509

---

site_id	AC6
Number of Residues	5
Details	binding site for residue CO B 402

Chain	Residue
B	KCX137
B	HIS170
B	HIS199
B	FE2401
B	HOH509

---

site_id	AC7
Number of Residues	4
Details	binding site for residue EDO B 403

Chain	Residue
B	ASN172
B	ALA173
B	ASP202
B	PHE229

---

site_id	AC8
Number of Residues	5
Details	binding site for residue GOL B 404

Chain	Residue
B	ASN160
B	LYS164
B	GLY189
B	VAL190
B	ASP191

---

site_id	AC9
Number of Residues	5
Details	binding site for residue FE2 C 401

Chain	Residue
C	HIS22
C	HIS24
C	KCX137
C	ASP256
C	CO402

---

site_id	AD1
Number of Residues	4
Details	binding site for residue CO C 402

Chain	Residue
C	KCX137
C	HIS170
C	HIS199
C	FE2401

---

site_id	AD2
Number of Residues	6
Details	binding site for residue GOL C 403

Chain	Residue
C	ASN160
C	LYS164
C	GLY189
C	VAL190
C	ASP191
C	LYS194

---

site_id	AD3
Number of Residues	5
Details	binding site for residue FE2 D 401

Chain	Residue
D	HIS22
D	HIS24
D	KCX137
D	ASP256
D	CO402

---

site_id	AD4
Number of Residues	5
Details	binding site for residue CO D 402

Chain	Residue
D	TRP97
D	KCX137
D	HIS170
D	HIS199
D	FE2401

---

site_id	AD5
Number of Residues	5
Details	binding site for residue GOL D 403

Chain	Residue
D	ASN160
D	GLY189
D	VAL190
D	ASP191
D	LYS194

---

Functional Information from PROSITE/UniProt

site_id	PS01322
Number of Residues	9
Details	PHOSPHOTRIESTERASE_1 Phosphotriesterase family signature 1. GfTLiHEHL

Chain	Residue	Details
A	GLY17-LEU25

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"description":"via carbamate group","evidences":[{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00679","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---