5W2M

APOBEC3F Catalytic Domain Complex with a Single-Stranded DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
B	0003824	molecular_function	catalytic activity
B	0008270	molecular_function	zinc ion binding
B	0016787	molecular_function	hydrolase activity
C	0003824	molecular_function	catalytic activity
C	0008270	molecular_function	zinc ion binding
C	0016787	molecular_function	hydrolase activity
D	0003824	molecular_function	catalytic activity
D	0008270	molecular_function	zinc ion binding
D	0016787	molecular_function	hydrolase activity
J	0003824	molecular_function	catalytic activity
J	0008270	molecular_function	zinc ion binding
J	0016787	molecular_function	hydrolase activity
K	0003824	molecular_function	catalytic activity
K	0008270	molecular_function	zinc ion binding
K	0016787	molecular_function	hydrolase activity
L	0003824	molecular_function	catalytic activity
L	0008270	molecular_function	zinc ion binding
L	0016787	molecular_function	hydrolase activity
M	0003824	molecular_function	catalytic activity
M	0008270	molecular_function	zinc ion binding
M	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue ZN A 801

Chain	Residue
A	HIS247
A	HIS249
C	HIS228

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site_id	AC2
Number of Residues	3
Details	binding site for residue ZN B 801

Chain	Residue
B	HIS247
B	HIS249
D	HIS228

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site_id	AC3
Number of Residues	3
Details	binding site for residue ZN J 801

Chain	Residue
J	HIS247
J	HIS249
L	HIS228

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site_id	AC4
Number of Residues	3
Details	binding site for residue ZN K 801

Chain	Residue
K	HIS247
K	HIS249
M	HIS228

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Functional Information from PROSITE/UniProt

site_id	PS00903
Number of Residues	39
Details	CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAErcFLswfcddilspntnyevtwytsws..........PCpe......CageV

Chain	Residue	Details
A	HIS249-VAL287

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01083

Chain	Residue	Details
A	GLU251
B	GLU251
C	GLU251
D	GLU251
J	GLU251
K	GLU251
L	GLU251
M	GLU251

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site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01083, ECO:0000269|PubMed:27139641

Chain	Residue	Details
A	HIS249
D	HIS249
D	CYS280
D	CYS283
J	HIS249
J	CYS280
J	CYS283
K	HIS249
K	CYS280
K	CYS283
L	HIS249
A	CYS280
L	CYS280
L	CYS283
M	HIS249
M	CYS280
M	CYS283
A	CYS283
B	HIS249
B	CYS280
B	CYS283
C	HIS249
C	CYS280
C	CYS283

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