5W2I
Crystal structure of the core catalytic domain of human inositol phosphate multikinase soaked with C4-analogue of PtdIns(4,5)P2 and ADP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 701 |
| Chain | Residue |
| A | ASP385 |
| A | MG702 |
| A | ADP703 |
| A | HOH826 |
| A | HOH855 |
| A | HOH906 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 702 |
| Chain | Residue |
| A | HOH801 |
| A | HOH887 |
| A | HOH913 |
| A | HOH928 |
| A | ASP385 |
| A | MG701 |
| A | ADP703 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue ADP A 703 |
| Chain | Residue |
| A | ILE65 |
| A | LYS75 |
| A | PRO111 |
| A | GLU131 |
| A | ASP132 |
| A | VAL133 |
| A | ASP144 |
| A | LEU254 |
| A | ASP385 |
| A | MG701 |
| A | MG702 |
| A | HOH801 |
| A | HOH811 |
| A | HOH826 |
| A | HOH841 |
| A | HOH855 |
| A | HOH874 |
| A | HOH906 |
| A | HOH928 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue I3P A 704 |
| Chain | Residue |
| A | ARG82 |
| A | LYS146 |
| A | LYS160 |
| A | GLN163 |
| A | GLN164 |
| A | LYS167 |
| A | GLN196 |
| A | ALA250 |
| A | HIS388 |
| A | HOH834 |
| A | HOH837 |
| A | HOH838 |
| A | HOH862 |
| A | HOH886 |
| A | HOH913 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28882892","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5W2H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5W2I","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28882892","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5W2H","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
