5W23

Crystal Structure of RSV F in complex with 5C4 Fab

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0019064	biological_process	fusion of virus membrane with host plasma membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue ZN A 601

Chain	Residue
A	LEU456
A	TYR458

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site_id	AC2
Number of Residues	1
Details	binding site for residue ZN B 601

Chain	Residue
B	ASN496

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site_id	AC3
Number of Residues	1
Details	binding site for residue ZN C 601

Chain	Residue
C	ASN175

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site_id	AC4
Number of Residues	2
Details	binding site for residue ZN J 301

Chain	Residue
J	ASP54
J	HIS56

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site_id	AC5
Number of Residues	1
Details	binding site for residue ZN J 302

Chain	Residue
J	ARG50

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site_id	AC6
Number of Residues	2
Details	binding site for residue ZN N 301

Chain	Residue
N	GLU27
N	GLU93

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	SITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11493675, ECO:0000269|PubMed:12127793

Chain	Residue	Details
A	ARG109
B	ARG109
C	ARG109

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site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11369882, ECO:0000269|PubMed:12127793

Chain	Residue	Details
A	ARG136
B	ARG136
C	ARG136

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site_id	SWS_FT_FI3
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636

Chain	Residue	Details
A	ASN27
B	ASN27
C	ASN27

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site_id	SWS_FT_FI4
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:28469033

Chain	Residue	Details
A	ASN70
B	ASN70
C	ASN70

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site_id	SWS_FT_FI5
Number of Residues	9
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255

Chain	Residue	Details
A	ASN116
A	ASN120
A	ASN126
B	ASN116
B	ASN120
B	ASN126
C	ASN116
C	ASN120
C	ASN126

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site_id	SWS_FT_FI6
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:24179220

Chain	Residue	Details
A	ASN500
B	ASN500
C	ASN500

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