5W16
Crystal structure of glutamate racemase from Thermus thermophilus in complex with D-glutamate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008881 | molecular_function | glutamate racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| A | 0047661 | molecular_function | amino-acid racemase activity |
| B | 0008881 | molecular_function | glutamate racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| B | 0047661 | molecular_function | amino-acid racemase activity |
| C | 0008881 | molecular_function | glutamate racemase activity |
| C | 0009252 | biological_process | peptidoglycan biosynthetic process |
| C | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| C | 0047661 | molecular_function | amino-acid racemase activity |
| D | 0008881 | molecular_function | glutamate racemase activity |
| D | 0009252 | biological_process | peptidoglycan biosynthetic process |
| D | 0016855 | molecular_function | racemase and epimerase activity, acting on amino acids and derivatives |
| D | 0047661 | molecular_function | amino-acid racemase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue DGL A 301 |
| Chain | Residue |
| A | ASP12 |
| A | CYS176 |
| A | THR177 |
| A | HOH428 |
| A | HOH461 |
| A | SER13 |
| A | PRO43 |
| A | TYR44 |
| A | GLY45 |
| A | CYS75 |
| A | ASN76 |
| A | THR77 |
| A | THR116 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 A 302 |
| Chain | Residue |
| A | GLY14 |
| A | VAL15 |
| A | THR39 |
| A | VAL42 |
| A | LEU238 |
| A | HOH443 |
| A | HOH482 |
| A | HOH519 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 A 303 |
| Chain | Residue |
| A | ALA40 |
| A | ARG41 |
| A | LYS47 |
| A | HOH468 |
| A | HOH528 |
| B | ALA40 |
| B | ARG41 |
| B | LYS47 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 A 304 |
| Chain | Residue |
| A | PRO48 |
| A | ALA50 |
| A | MET51 |
| A | ARG54 |
| B | ARG251 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 A 305 |
| Chain | Residue |
| A | LEU195 |
| A | LEU196 |
| A | ASP197 |
| A | GLU200 |
| A | HOH525 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 A 306 |
| Chain | Residue |
| A | ARG106 |
| A | VAL129 |
| A | ASP130 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 307 |
| Chain | Residue |
| A | GLN117 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residue DGL B 301 |
| Chain | Residue |
| B | ASP12 |
| B | SER13 |
| B | PRO43 |
| B | TYR44 |
| B | GLY45 |
| B | CYS75 |
| B | ASN76 |
| B | THR77 |
| B | THR116 |
| B | CYS176 |
| B | THR177 |
| B | HOH421 |
| B | HOH431 |
| B | HOH454 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue NO3 B 302 |
| Chain | Residue |
| B | GLY14 |
| B | VAL15 |
| B | THR39 |
| B | VAL42 |
| B | TYR235 |
| B | LEU238 |
| B | HOH420 |
| B | HOH467 |
| B | HOH511 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue NO3 B 303 |
| Chain | Residue |
| A | ARG251 |
| B | PRO48 |
| B | ALA50 |
| B | MET51 |
| B | ARG54 |
| B | HOH404 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 304 |
| Chain | Residue |
| B | THR116 |
| B | GLN117 |
| B | HOH559 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 305 |
| Chain | Residue |
| B | THR224 |
| site_id | AD4 |
| Number of Residues | 14 |
| Details | binding site for residue DGL C 301 |
| Chain | Residue |
| C | ASP12 |
| C | SER13 |
| C | PRO43 |
| C | TYR44 |
| C | GLY45 |
| C | CYS75 |
| C | ASN76 |
| C | THR77 |
| C | THR116 |
| C | CYS176 |
| C | THR177 |
| C | HOH407 |
| C | HOH417 |
| C | HOH424 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 C 302 |
| Chain | Residue |
| C | ALA40 |
| C | ARG41 |
| C | LYS47 |
| C | HOH507 |
| D | ALA40 |
| D | ARG41 |
| D | LYS47 |
| D | HOH455 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 C 303 |
| Chain | Residue |
| A | ARG221 |
| C | GLN66 |
| C | PHE225 |
| C | LEU227 |
| C | ARG250 |
| C | HOH420 |
| A | ARG30 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue NO3 C 304 |
| Chain | Residue |
| C | GLY14 |
| C | VAL15 |
| C | THR39 |
| C | VAL42 |
| C | LEU238 |
| C | HOH444 |
| C | HOH448 |
| C | HOH506 |
| C | HOH518 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 C 305 |
| Chain | Residue |
| C | PRO48 |
| C | ALA50 |
| C | MET51 |
| C | ARG54 |
| D | ARG251 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue NO3 C 306 |
| Chain | Residue |
| C | ALA87 |
| C | GLU88 |
| C | HOH478 |
| C | HOH524 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 307 |
| Chain | Residue |
| C | THR116 |
| C | GLN117 |
| C | HOH563 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue CL C 308 |
| Chain | Residue |
| C | VAL153 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 309 |
| Chain | Residue |
| C | ASP130 |
| C | HOH502 |
| site_id | AE4 |
| Number of Residues | 14 |
| Details | binding site for residue DGL D 301 |
| Chain | Residue |
| D | ASP12 |
| D | SER13 |
| D | PRO43 |
| D | TYR44 |
| D | GLY45 |
| D | CYS75 |
| D | ASN76 |
| D | THR77 |
| D | THR116 |
| D | CYS176 |
| D | THR177 |
| D | HOH420 |
| D | HOH423 |
| D | HOH454 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 D 302 |
| Chain | Residue |
| B | ARG30 |
| B | GLU219 |
| B | ARG221 |
| D | PHE225 |
| D | LEU227 |
| D | ARG250 |
| D | HOH445 |
| site_id | AE6 |
| Number of Residues | 9 |
| Details | binding site for residue NO3 D 303 |
| Chain | Residue |
| D | GLY14 |
| D | VAL15 |
| D | THR39 |
| D | VAL42 |
| D | LEU238 |
| D | HOH432 |
| D | HOH487 |
| D | HOH528 |
| D | HOH537 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 D 304 |
| Chain | Residue |
| C | ARG251 |
| D | PRO48 |
| D | ALA50 |
| D | MET51 |
| D | ARG54 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 D 305 |
| Chain | Residue |
| D | ARG106 |
| D | VAL129 |
| D | ASP130 |
| D | HOH418 |
| D | HOH529 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 306 |
| Chain | Residue |
| D | THR116 |
| D | GLN117 |
| D | HOH558 |
| site_id | AF1 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 307 |
| Chain | Residue |
| D | ARG54 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00258","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00258","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
