5W0L
CREBBP Bromodomain in complex with Cpd10 (1-(3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0004402 | molecular_function | histone acetyltransferase activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue 9UD A 1201 |
| Chain | Residue |
| A | LEU1109 |
| A | PRO1110 |
| A | ASN1168 |
| A | ARG1173 |
| A | VAL1174 |
| A | HOH1311 |
| A | HOH1361 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue 9UD B 1201 |
| Chain | Residue |
| B | ASN1168 |
| B | ARG1173 |
| B | VAL1174 |
| B | HOH1307 |
| B | HOH1362 |
| B | HOH1366 |
| B | LEU1109 |
| B | PRO1110 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY |
| Chain | Residue | Details |
| A | SER1108-TYR1167 | |
