5VXT
Crystal structure of catechol 1,2-dioxygenase from Burkholderia ambifaria
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| A | 0008199 | molecular_function | ferric iron binding |
| A | 0009712 | biological_process | catechol-containing compound metabolic process |
| A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| A | 0018576 | molecular_function | catechol 1,2-dioxygenase activity |
| A | 0019614 | biological_process | catechol-containing compound catabolic process |
| A | 0042952 | biological_process | beta-ketoadipate pathway |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| B | 0008199 | molecular_function | ferric iron binding |
| B | 0009712 | biological_process | catechol-containing compound metabolic process |
| B | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| B | 0018576 | molecular_function | catechol 1,2-dioxygenase activity |
| B | 0019614 | biological_process | catechol-containing compound catabolic process |
| B | 0042952 | biological_process | beta-ketoadipate pathway |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue PTY A 401 |
| Chain | Residue |
| A | GLU60 |
| B | PTY401 |
| A | TYR67 |
| A | ALA77 |
| A | ARG220 |
| A | HOH611 |
| A | HOH710 |
| B | ILE39 |
| B | LEU43 |
| B | ALA77 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue FE A 402 |
| Chain | Residue |
| A | TYR170 |
| A | HIS230 |
| A | HIS232 |
| A | CAQ403 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue CAQ A 403 |
| Chain | Residue |
| A | LEU79 |
| A | PRO114 |
| A | TYR170 |
| A | ARG227 |
| A | HIS230 |
| A | HIS232 |
| A | GLN246 |
| A | FE402 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | PHE173 |
| A | HOH551 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | GLN38 |
| A | HOH540 |
| A | HOH679 |
| A | HOH727 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 406 |
| Chain | Residue |
| A | HIS172 |
| A | GLN179 |
| A | HOH503 |
| A | HOH582 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | binding site for residue PTY B 401 |
| Chain | Residue |
| A | ILE39 |
| A | LEU43 |
| A | LEU44 |
| A | ASP46 |
| A | PTY401 |
| B | LEU43 |
| B | ASP46 |
| B | GLU60 |
| B | TYR67 |
| B | GLN216 |
| B | ARG220 |
| B | HOH519 |
| B | HOH593 |
| B | HOH648 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue FE B 402 |
| Chain | Residue |
| B | TYR170 |
| B | HIS230 |
| B | HIS232 |
| B | CAQ403 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue CAQ B 403 |
| Chain | Residue |
| B | LEU79 |
| B | PRO114 |
| B | LEU115 |
| B | TYR170 |
| B | ARG227 |
| B | HIS230 |
| B | HIS232 |
| B | FE402 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | GLY148 |
| B | LEU149 |
| B | HIS240 |
| B | PRO298 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | ILE255 |
| B | ASP258 |
| B | TYR261 |
| B | ALA262 |
| B | THR263 |
Functional Information from PROSITE/UniProt
| site_id | PS00083 |
| Number of Residues | 29 |
| Details | INTRADIOL_DIOXYGENAS Intradiol ring-cleavage dioxygenases signature. IhGtVtgldGkpVagalVECwhanshGfY |
| Chain | Residue | Details |
| A | ILE142-TYR170 |
